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Author: Mei-Ling Ting Lee
Publisher: Springer Science & Business Media
ISBN: 1461489814
Category : Medical
Languages : en
Pages : 446
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Book Description
Methods of risk analysis and the outcome of particular evaluations and predictions are covered in detail in this proceedings volume, whose contributions are based on invited presentations from Professor Mei-Ling Ting Lee's 2011 symposium on Risk Analysis and the Evaluation of Predictions. This symposium was held at the University of Maryland in October of 2011. Risk analysis is the science of evaluating health, environmental, and engineering risks resulting from past, current, or anticipated, future activities. The use of these evaluations include to provide information for determining regulatory actions to limit risk, present scientific evidence in legal settings, evaluate products and potential liabilities within private organizations, resolve World Trade disputes amongst nations, and educate the public concerning particular risk issues. Risk analysis is an interdisciplinary science that relies on epidemiology and laboratory studies, collection of exposure and other field data, computer modeling, and related social, economic and communication considerations. In addition, social dimensions of risk are addressed by social scientists.
Author: Mei-Ling Ting Lee
Publisher: Springer Science & Business Media
ISBN: 1461489814
Category : Medical
Languages : en
Pages : 446
Get Book Here
Book Description
Methods of risk analysis and the outcome of particular evaluations and predictions are covered in detail in this proceedings volume, whose contributions are based on invited presentations from Professor Mei-Ling Ting Lee's 2011 symposium on Risk Analysis and the Evaluation of Predictions. This symposium was held at the University of Maryland in October of 2011. Risk analysis is the science of evaluating health, environmental, and engineering risks resulting from past, current, or anticipated, future activities. The use of these evaluations include to provide information for determining regulatory actions to limit risk, present scientific evidence in legal settings, evaluate products and potential liabilities within private organizations, resolve World Trade disputes amongst nations, and educate the public concerning particular risk issues. Risk analysis is an interdisciplinary science that relies on epidemiology and laboratory studies, collection of exposure and other field data, computer modeling, and related social, economic and communication considerations. In addition, social dimensions of risk are addressed by social scientists.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309167949
Category : Science
Languages : en
Pages : 180
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Book Description
The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.
Author: National Research Council
Publisher: National Academies Press
ISBN: 030904894X
Category : Science
Languages : en
Pages : 668
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Book Description
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Author: J. Stephen Wormith
Publisher: John Wiley & Sons
ISBN: 1119315719
Category : Psychology
Languages : en
Pages : 608
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Book Description
A comprehensive guide to the theory, research and practice of violence risk management The Wiley Handbook of What Works in Violence Risk Management: Theory, Research and Practice offers a comprehensive guide to the theory, research and practice of violence risk management. With contributions from a panel of noted international experts, the book explores the most recent advances to the theoretical understanding, assessment and management of violent behavior. Designed to be an accessible resource, the highly readable chapters address common issues associated with violent behavior such as alcohol misuse and the less common issues for example offenders with intellectual disabilities. Written for both those new to the field and professionals with years of experience, the book offers a wide-ranging review of who commit acts of violence, their prevalence in society and the most recent explanations for their behavior. The contributors explore various assessment approaches and highlight specialized risk assessment instruments. The Handbook provides the latest evidence on effective treatment and risk management and includes a number of well-established and effective treatment interventions for violent offenders. This important book: Contains an authoritative and comprehensive guide to the topic Includes contributions from an international panel of experts Offers information on violence risk formulation Reveals the most recent techniques in violence risk assessment Explains what works in violence intervention Reviews specialty clinical assessments Written for clinicians and other professionals in the field of violence prevention and assessment, The Wiley Handbook of What Works in Violence Risk Management is unique in its approach because it offers a comprehensive review of the topic rather than like other books on the market that take a narrower view.
Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Category : Science
Languages : en
Pages : 422
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Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309161525
Category : Political Science
Languages : en
Pages : 161
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Book Description
The events of September 11, 2001 changed perceptions, rearranged national priorities, and produced significant new government entities, including the U.S. Department of Homeland Security (DHS) created in 2003. While the principal mission of DHS is to lead efforts to secure the nation against those forces that wish to do harm, the department also has responsibilities in regard to preparation for and response to other hazards and disasters, such as floods, earthquakes, and other "natural" disasters. Whether in the context of preparedness, response or recovery from terrorism, illegal entry to the country, or natural disasters, DHS is committed to processes and methods that feature risk assessment as a critical component for making better-informed decisions. Review of the Department of Homeland Security's Approach to Risk Analysis explores how DHS is building its capabilities in risk analysis to inform decision making. The department uses risk analysis to inform decisions ranging from high-level policy choices to fine-scale protocols that guide the minute-by-minute actions of DHS employees. Although DHS is responsible for mitigating a range of threats, natural disasters, and pandemics, its risk analysis efforts are weighted heavily toward terrorism. In addition to assessing the capability of DHS risk analysis methods to support decision-making, the book evaluates the quality of the current approach to estimating risk and discusses how to improve current risk analysis procedures. Review of the Department of Homeland Security's Approach to Risk Analysis recommends that DHS continue to build its integrated risk management framework. It also suggests that the department improve the way models are developed and used and follow time-tested scientific practices, among other recommendations.
Author: Huixiao Hong
Publisher: Elsevier
ISBN: 044315340X
Category : Science
Languages : en
Pages : 566
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Book Description
QSAR in Safety Evaluation and Risk Assessment provides comprehensive coverage on QSAR methods, tools, data sources, and models focusing on applications in products safety evaluation and chemicals risk assessment. Organized into five parts, the book covers almost all aspects of QSAR modeling and application. Topics in the book include methods of QSAR, from both scientific and regulatory viewpoints; data sources available for facilitating QSAR models development; software tools for QSAR development; and QSAR models developed for assisting safety evaluation and risk assessment. Chapter contributors are authored by a lineup of active scientists in this field. The chapters not only provide professional level technical summarizations but also cover introductory descriptions for all aspects of QSAR for safety evaluation and risk assessment. - Provides comprehensive content about the QSAR techniques and models in facilitating the safety evaluation of drugs and consumer products and risk assesment of environmental chemicals - Includes some of the most cutting-edge methodologies such as deep learning and machine learning for QSAR - Offers detailed procedures of modeling and provides examples of each model's application in real practice
Author: Terrence Adam
Publisher: Springer Nature
ISBN: 3030186261
Category : Medical
Languages : en
Pages : 349
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Book Description
This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.
Author: Alok A. Khorana
Publisher: CRC Press
ISBN: 1420048007
Category : Medical
Languages : en
Pages : 290
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Book Description
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
Author: David Woolley
Publisher: CRC Press
ISBN: 1498709303
Category : Medical
Languages : en
Pages : 553
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Book Description
Practical Toxicology: Evaluation, Prediction, and Risk, Third Edition shows how to conduct a program of safety evaluation and testing and then to interpret and apply the resulting data and information in the real world, beginning with the basic concepts in toxicology and progressing to the interpretation of the resulting data. Revised and updated chapters on risk assessment guide the reader to setting the foundations necessary for submission to regulatory authorities. In addition, a new chapter in the book reviews the errors in toxicology, mistakes, misuse, mismanagement, and misunderstanding with a view to avoiding these in the future. New Chapters in the Third Edition: Toxicology in silico Errors in Toxicology Safety Assessment of Extractables and Leachables. This new edition follows a practical sequence from introducing the basics of toxicology (including the vital concept of normality in controls) to describing a test program and then interpreting the data and translating that to risk assessment that can be used in a number of real world situations where safety and secure risk assessment are essential. Although written primarily from the perspective of pharmaceutical development, the test designs and toxicological problems encountered in that field are entirely relevant to those with other classes of chemicals, the only difference being the regulatory context. Toxicology is an international discipline and the book has been written to take into account some of the differences in regulatory nuance between the main regions of the world. Completely revised and written in an easily accessible style, the text address several audiences—from students and post-graduates coming to the subject for the first time to established professionals who find themselves needing to learn about toxicology, toxicity testing, interpretation of the results, and risk assessment. It is intended primarily as a textbook, with case studies and information on where to go to ask questions, but can also be used as a practical reference book. It covers all the basics of toxicology and the main aspects of safety evaluation testing and risk assessment while reviewing critically the current state of the discipline. It also provides a foundation for those seeking registration or certification.
