Testing for Abuse Liability of Drugs in Humans PDF Download
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Author: Marian W. Fischman
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 420
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Book Description
Representatives from industry, academia and government discuss issues related to testing for drug abuse liability and dependence potential. Contributors critically assess current methods for evaluating drugs in human subjects and describe both the advantages and limitations of each approach. This information permits identification of areas in which further research and development are needed.
Author: Marian W. Fischman
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 420
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Book Description
Representatives from industry, academia and government discuss issues related to testing for drug abuse liability and dependence potential. Contributors critically assess current methods for evaluating drugs in human subjects and describe both the advantages and limitations of each approach. This information permits identification of areas in which further research and development are needed.
Author: Mariam W. Fischman
Publisher:
ISBN:
Category :
Languages : en
Pages : 398
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Committee on Problems of Drug Dependence (U.S.)
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 172
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Book Description
Author: Carrie Markgraf
Publisher: Academic Press
ISBN: 0124202160
Category : Medical
Languages : en
Pages : 321
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Book Description
Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability. Provides a consolidated overview of the complex regulatory landscape Offers best practice methodology for conducting animal studies, including selection of doses and positive control agents that will help you improve your own abuse potential studies Includes real-life examples to illustrate how nonclinical data fit into the submission strategy
Author:
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 153
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Book Description
Author: International Council on Alcohol and Addictions
Publisher:
ISBN:
Category :
Languages : en
Pages : 111
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Book Description
Author: Joseph V. Brady
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 154
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Book Description
Author: Jordi Camí
Publisher:
ISBN:
Category :
Languages : en
Pages : 143
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Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309055334
Category : Medical
Languages : en
Pages : 330
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Book Description
Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.
