Prehabilitation in Patients Undergoing Surgery for Hepatobiliary Or Pancreatic Cancer

Prehabilitation in Patients Undergoing Surgery for Hepatobiliary Or Pancreatic Cancer PDF Author: Tram Bui Ngoc
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
In patients with hepatobiliary and pancreatic cancers, surgery is the only potential curative treatment for resection candidates (Benson et al., 2009; Freelove & Walling, 2006). A five-year research experience in patients undergoing surgery for colorectal cancer found that prehabilitation led to faster return to preoperative walking capacity than rehabilitation (Minnella et al., 2017). There has been no studies thus far evaluating the impact of a trimodal prehabilitation program on functional recovery in patients undergoing hepatobiliary or pancreatic cancer surgery. Our goal was to determine the impact of prehabilitation on the functional exercise capacity of these patients. We performed a randomized controlled pilot trial comparing the impact of a prehabilitation program begun four weeks before surgery, to the same program (rehabilitation) initiated right after surgery. The program was maintained by both groups until eight weeks postoperatively. We hypothesized our prehabilitation program would improve 6-minute walk test performance preoperatively. Furthermore, at eight weeks post-surgery, we hypothesized greater 6-minute walk performance in the prehabilitation group compared to the rehabilitation group. Thirty-five participants were randomized to receive prehabilitation or rehabilitation. We found that preoperatively, the prehabilitation group demonstrated a clinically meaningful improvement in 6-minute walk distance. At four-weeks after surgery, the rehabilitation group experienced a statistically and clinically significant decrease in mean 6-minute walk distance from baseline, whereas the prehabilitation group was able to maintain its baseline walking capacity. Our findings suggest that a prehabilitation program in hepatobiliary and pancreatic cancer patients can deliver meaningful changes in pre- and postoperative functional exercise capacity.

Prehabilitation in Patients Undergoing Surgery for Hepatobiliary Or Pancreatic Cancer

Prehabilitation in Patients Undergoing Surgery for Hepatobiliary Or Pancreatic Cancer PDF Author: Tram Bui Ngoc
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
In patients with hepatobiliary and pancreatic cancers, surgery is the only potential curative treatment for resection candidates (Benson et al., 2009; Freelove & Walling, 2006). A five-year research experience in patients undergoing surgery for colorectal cancer found that prehabilitation led to faster return to preoperative walking capacity than rehabilitation (Minnella et al., 2017). There has been no studies thus far evaluating the impact of a trimodal prehabilitation program on functional recovery in patients undergoing hepatobiliary or pancreatic cancer surgery. Our goal was to determine the impact of prehabilitation on the functional exercise capacity of these patients. We performed a randomized controlled pilot trial comparing the impact of a prehabilitation program begun four weeks before surgery, to the same program (rehabilitation) initiated right after surgery. The program was maintained by both groups until eight weeks postoperatively. We hypothesized our prehabilitation program would improve 6-minute walk test performance preoperatively. Furthermore, at eight weeks post-surgery, we hypothesized greater 6-minute walk performance in the prehabilitation group compared to the rehabilitation group. Thirty-five participants were randomized to receive prehabilitation or rehabilitation. We found that preoperatively, the prehabilitation group demonstrated a clinically meaningful improvement in 6-minute walk distance. At four-weeks after surgery, the rehabilitation group experienced a statistically and clinically significant decrease in mean 6-minute walk distance from baseline, whereas the prehabilitation group was able to maintain its baseline walking capacity. Our findings suggest that a prehabilitation program in hepatobiliary and pancreatic cancer patients can deliver meaningful changes in pre- and postoperative functional exercise capacity.

01 - IMPACT OF A TRIMODAL PREHABILITATION PROGRAM ON FUNCTIONAL RECOVERY AFTER HEPATOBILIARY AND PANCREATIC CANCER SURGERY: PRELIMINARY FINDINGS FROM A RANDOMIZED CONTROLLED PILOT TRIAL

01 - IMPACT OF A TRIMODAL PREHABILITATION PROGRAM ON FUNCTIONAL RECOVERY AFTER HEPATOBILIARY AND PANCREATIC CANCER SURGERY: PRELIMINARY FINDINGS FROM A RANDOMIZED CONTROLLED PILOT TRIAL PDF Author: Tram Bui
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
Introduction: No studies thus far have evaluated the impact of a supervised trimodal prehabilitation program on functional exercise capacity in hepatobiliary and pancreatic cancer patients undergoing surgery.Methods: A single-centre, parallel-arm randomized controlled pilot trial was conducted. Patients were assigned to either a prehabilitation or rehabilitation program. The prehabilitation group received a trimodal program comprising exercise (once-weekly supervised and home-based), nutritional counselling with whey protein supplementation, and relaxation exercises initiated 4 weeks before surgery. The rehabilitation group received the same trimodal program (minus once-weekly supervised exercise) initiated immediately after surgery. Both study arms continued the program for 8 weeks after surgery. The primary outcome was functional exercise capacity measured using the 6-minute walk test (6MWT).Results: Thirty-five patients were randomized to receive prehabilitation (n=17) or rehabilitation (n=18). The prehabilitation group demonstrated a clinically meaningful improvement (+19.6 m [SE 0.2]; p =0.061) in 6MWT from baseline to pre-operative assessment. Both groups were comparable in age, gender, appendicular skeletal muscle index and baseline 6MWT. The rehabilitation group experienced a statistically and clinically significant decrease in mean 6MWT from baseline to the 4-wk post-operative assessment (-23.72 m [SE, 0.36]; p=0.035), whereas the prehabilitation group was able to maintain their baseline walking capacity (-0.11 m [SE 0.3]; p=0.991).Conclusion: A prehabilitation program in hepatobiliary and pancreatic cancer patients can deliver meaningful changes in pre and postoperative functional exercise capacity.

Prehabilitation for Cancer Surgery

Prehabilitation for Cancer Surgery PDF Author: Arunangshu Chakraborty
Publisher: Springer Nature
ISBN: 9811664943
Category : Medical
Languages : en
Pages : 346

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Book Description
This book explores the concept of prehabilitation to great depths using all possible modes of prehabilitation across surgical specialities. Prehabilitation is a unique concept that is becoming popular day-by-day. It began from the enhanced recovery after surgery (ERAS) program and has found importance in almost all of the surgeries now. The book possibly being the first on prehabilitation globally introduces the concept, describes the methods of functional assessment of the patients scheduled for extensive cancer surgery, and ways of pre-optimisation. It covers the methods of prehabilitation system-wise and then provides pehabilitation tools specific for individual onco-surgical subspecialties. The book will be an invaluable resource for practitioners of onco-anesthesia and onco-surgery in optimizing their patients before surgery for best results. It will also be useful for the allied disciplines such as nutritionists, physiotherapists, psychiatrists and oncology nurses.

Prehabilitation for Cancer Surgery

Prehabilitation for Cancer Surgery PDF Author: Arunangshu Chakraborty
Publisher: Springer
ISBN: 9789811664960
Category : Medical
Languages : en
Pages : 0

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Book Description
This book explores the concept of prehabilitation to great depths using all possible modes of prehabilitation across surgical specialities. Prehabilitation is a unique concept that is becoming popular day-by-day. It began from the enhanced recovery after surgery (ERAS) program and has found importance in almost all of the surgeries now. The book possibly being the first on prehabilitation globally introduces the concept, describes the methods of functional assessment of the patients scheduled for extensive cancer surgery, and ways of pre-optimisation. It covers the methods of prehabilitation system-wise and then provides pehabilitation tools specific for individual onco-surgical subspecialties. The book will be an invaluable resource for practitioners of onco-anesthesia and onco-surgery in optimizing their patients before surgery for best results. It will also be useful for the allied disciplines such as nutritionists, physiotherapists, psychiatrists and oncology nurses.

Textbook of Pancreatic Cancer

Textbook of Pancreatic Cancer PDF Author: Kjetil Søreide
Publisher: Springer Nature
ISBN: 3030537862
Category : Medical
Languages : en
Pages : 1320

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Book Description
This textbook provides a practically applicable resource for understanding the surgical oncology management of pancreatic cancer. It discusses relevant aspects of anatomy and pathophysiology along with the latest diagnostic techniques. Insightful descriptions are then provided detailing how to perform critical surgical procedures when treating these patients. Relevant perioperative management strategies and emerging themes in cancer biology critical to understanding and treating the disease are also described. The need for cross-discipline collaboration to facilitate and enhance innovation within the discipline is reinforced throughout the text. Each chapter presents the relevant current clinical standards along with areas of controversy in both research and clinical practice within “pearls and pitfalls” sections. Textbook of Pancreatic Cancer: Principles and Practice of Surgical Oncology is a detailed work covering the basic material important to trainees as well as advanced curriculum for established specialists in the field from a multi-disciplinary perspective. Therefore, it is crucial resource for all practicing and trainee professionals who encounter these patients in their day-to-day clinical practice.

Hepatobiliary and Pancreatic Cancer

Hepatobiliary and Pancreatic Cancer PDF Author: Daniele Regge
Publisher: Springer
ISBN: 3319502964
Category : Medical
Languages : en
Pages : 127

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Book Description
This book describes the pathways of dissemination of primary liver, biliary, and pancreatic neoplasms and proposes a practical and clinically driven approach to their imaging. The typical dissemination pathways for hepatocellular carcinoma, cholangiocarcinoma, exocrine pancreatic carcinoma, and neuroendocrine pancreatic tumors are systematically reviewed, and more unusual pathways are also documented. The content is presented in an extremely schematic way, with numerous high-quality graphical illustrations and multimodality images (US, CT, MRI, and PET) that are accompanied by clear explanatory text. The clinical significance of findings and potential therapeutic options are explained whenever appropriate. In addition, relevant background information is provided on the role of morphopathological drivers of cancer spread and anatomy.

Handbook of Hepato-Pancreato-Biliary Surgery

Handbook of Hepato-Pancreato-Biliary Surgery PDF Author: Nicholas J. Zyromski
Publisher: Lippincott Williams & Wilkins
ISBN: 1469873508
Category : Medical
Languages : en
Pages : 697

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Book Description
This handbook provides a comprehesive but succinct overview of medical and surgical management of diseases of the liver, pancreas, and biliary tree. It includes imaging of the pancreas and hepatobiliary system as well. Open and minimally invasive surgical management techniques are covered. Coverage includes pancreatic cancer and cysts, pancreatitis, complications of panreatic surgery, ultrasound for liver disease, cirrhosis and portal hypertension, neuroendocrine and colorectal metastases to the liver, gallstones, cholesystitis, infections in biliary surgery, and more. Target markets include surgical residents, surgical nurses, beginning fellows in HPB training programs. There may also be some uptake from gastroenterologists.

Textbook of Onco-Anesthesiology

Textbook of Onco-Anesthesiology PDF Author: Rakesh Garg
Publisher: Springer Nature
ISBN: 9811600066
Category : Medical
Languages : en
Pages : 539

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Book Description
This book covers all essential evidence on perioperative care and anesthetic concerns for cancer surgeries, including the evaluation and assessment of patients’ schedule for cancer surgeries, perioperative anesthetic management of various cancers, perioperative analgesia for cancer surgeries, and issues related to inoperable cancers. It reviews anesthetic considerations of all cancer types as there is a wide variation in anesthetic requirements in this subset of patients. Cancer surgeries are on the rise worldwide and healthcare facilities with cancer as a core specialty are emerging quickly around the globe. As cancer is on rise and efficient surgical management is available, more and more patients are being treated surgically. However, cancer surgeries are complicated, have varied concerns and these are not covered sufficiently in presently available textbooks of anesthesiology. This book fulfills the growing need for complete and comprehensive textbook of onco-anesthesia and fills the gap in the current texts that do not exclusively cover anesthesia for cancer surgeries. This textbook serves as a comprehensive but quick guide for trainee residents/fellows and practicing anesthesiologists, clinicians and surgeons.

Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation

Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation PDF Author: Zoka Milan
Publisher: Springer Nature
ISBN: 3030513319
Category : Medical
Languages : en
Pages : 467

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Book Description
This concise, accessible book covers anesthesia for hepatico-pancreatic-biliary (HPB) surgery and transplantation, based on randomized clinical trials, meta-analyses, case series, reports, and hands-on experience. The anatomy, physiology, pathophysiology and clinical consequences are discussed, and the close ties between HPB resection and transplant anesthesia are explored. The content reflects current real-world practice, as liver and pancreatic transplant surgeries have substantially improved in terms of blood-loss reduction, fast tracking and reduced risk. The book also addresses anesthetic aspects in connection with the recently introduced and rapidly expanding practice of laparoscopic surgery; with enhanced recovery; and with pancreatic surgery. Anesthesia for Hepatico-Pancreatic-Biliary Surgery and Transplantation is intended for aspiring HPB and transplant anesthetists, anesthesia trainees, and consultants with experience in HPB anesthesia who want to see whether or not they’re up to date on the current standards.

Seminars in Dysphagia

Seminars in Dysphagia PDF Author: Renee Speyer
Publisher: BoD – Books on Demand
ISBN: 9535121510
Category : Medical
Languages : en
Pages : 250

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Book Description
Seminars in Dysphagia provides a comprehensive overview of contemporary issues in the field of dysphagia assessment, treatment and management in diverse subject populations. Expert views are shared by international clinical experts from different medical and allied health fields. This book contains an introductory chapter on the anatomical structures and physiology processes that underpin dysphagia and discusses the effects of polypharmacy and ageing on deglutition. Contemporary practices of functional assessment of swallowing and the endoscopic assessment for both oropharyngeal and esophageal dysphagia are reviewed. Both the nutritional support and decision making in oral route are described and the impact of dysphagia on carers and family when managing dysphagia. Several chapters are dedicated to outlining the manifestation and consequences of dysphagia in specific populations, including persons with Parkinsons disease, dystonia, chronic obstructive pulmonary disease and mixed connective tissue disease.