Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices PDF Author: J Pan
Publisher: Elsevier
ISBN: 1782420258
Category : Technology & Engineering
Languages : en
Pages : 271

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Book Description
The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. - Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed - Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices PDF Author: J Pan
Publisher: Elsevier
ISBN: 1782420258
Category : Technology & Engineering
Languages : en
Pages : 271

Get Book Here

Book Description
The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. - Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed - Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Bioresorbable Polymers for Biomedical Applications

Bioresorbable Polymers for Biomedical Applications PDF Author: Giuseppe Perale
Publisher: Woodhead Publishing
ISBN: 0081002661
Category : Technology & Engineering
Languages : en
Pages : 630

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Book Description
Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. - Focuses on biomedical applications of bioresorbable polymers - Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications - Provides balanced coverage of the field with contributions from academia and industry - Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers PDF Author: Xiang Cheng Zhang
Publisher: Woodhead Publishing
ISBN: 0081003935
Category : Technology & Engineering
Languages : en
Pages : 478

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Book Description
Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. - Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine - Contains comprehensive coverage of material properties, including unique insights into modeling degradation - Written by an eclectic mix of international authors with experience in academia and industry

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites

A Phenomenological Mathematical Modelling Framework for the Degradation of Bioresorbable Composites PDF Author: Ismael Moreno-Gomez
Publisher: Springer
ISBN: 3030049906
Category : Technology & Engineering
Languages : en
Pages : 361

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Book Description
This book presents a generalised computational model for the degradation of resorbable composites, using analytic expressions to represent the interwoven phenomena present during degradation. It then combines this modelling framework with a comprehensive database of quantitative degradation data mined from existing literature and from novel experiments, to provide new insights into the interrelated factors controlling degradation. Resorbable composites made of biodegradable polyesters and calcium-based ceramics have significant therapeutic potential as tissue engineering scaffolds, as temporary implants and as drug-loaded matrices for controlled release. However, their degradation is complex and the rate of resorption depends on multiple connected factors such as the shape and size of the device, polymer chemistry and molecular weight, particle phase, size, volume fraction, distribution and pH-dependent dissolution properties. Understanding and ultimately predicting the degradation of resorbable composites is of central importance if we are to fully unlock the promise of these materials.

Bioresorbable Polymers and their Composites

Bioresorbable Polymers and their Composites PDF Author: Deepak Verma
Publisher: Elsevier
ISBN: 0443189161
Category : Technology & Engineering
Languages : en
Pages : 538

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Book Description
Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer. This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices. - Introduces the reader to various processing and modeling techniques for bioresorbable polymers, including electrospinning, molecular and finite element modeling - Covers a range of key bioresorbable composites, such as PCL, PLA/PLLA and PHA/PHB/PHBV - Explores a wide selection of biomedical applications of bioresorbable polymers, from tissue engineering and stents, to biosensors and medical devices/implants

Materials for Biomedical Engineering: Absorbable Polymers

Materials for Biomedical Engineering: Absorbable Polymers PDF Author: Alexandru Grumezescu
Publisher: Elsevier
ISBN: 0128184167
Category : Technology & Engineering
Languages : en
Pages : 457

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Book Description
Materials for Biomedical Engineering: Absorbable Polymers provides a detailed and comprehensive review of recent progress in absorbable biopolymers and their impact on biomedical engineering. The book's main focus lies in their classification, processing, properties and performance, biocompatibility, and their applications in tissue engineering, drug delivery, bone repair and regenerative medicine. The most up-to-date methods used to obtain such polymers and how to improve their properties is discussed in detail. This book provides readers with a comprehensive and updated review of the latest research in the field of absorbable polymers for biomedical applications. - Provides knowledge of the range of absorbable polymers currently available, enabling the reader to make optimal materials selection decisions - Presents detailed information on current and proposed applications of the latest developments - Includes a strong emphasis on chemistry and physico-chemical characterization of these materials and their application in biomedical engineering

Shape Memory Polymers for Biomedical Applications

Shape Memory Polymers for Biomedical Applications PDF Author: L Yahia
Publisher: Elsevier
ISBN: 0857097059
Category : Technology & Engineering
Languages : en
Pages : 325

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Book Description
Shape memory polymers (SMPs) are an emerging class of smart polymers which give scientists the ability to process the material into a permanent state and predefine a second temporary state which can be triggered by different stimuli. The changing chemistries of SMPs allows scientists to tailor important properties such as strength, stiffness, elasticity and expansion rate. Consequently SMPs are being increasingly used and developed for minimally invasive applications where the material can expand and develop post insertion. This book will provide readers with a comprehensive review of shape memory polymer technologies. Part 1 will discuss the fundamentals and mechanical aspects of SMPs. Chapters in part 2 will look at the range of technologies and materials available for scientific manipulation whilst the final set of chapters will review applications. - Reviews the fundamentals of shape memory polymers with chapters focussing on the basic principles of the materials - Comprehensive coverage of design and mechanical aspects of SMPs - Expert analysis of the range of technologies and materials available for scientific manipulation

Materials and Devices for Bone Disorders

Materials and Devices for Bone Disorders PDF Author: Susmita Bose
Publisher: Academic Press
ISBN: 0128028033
Category : Technology & Engineering
Languages : en
Pages : 561

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Book Description
Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. - Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context - Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts - Includes input from a world-class team of research scientists, engineers, and clinicians - Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders

Medical Devices

Medical Devices PDF Author: Seeram Ramakrishna
Publisher: Woodhead Publishing
ISBN: 0081002912
Category : Medical
Languages : en
Pages : 253

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Book Description
Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors' practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. - Provides readers with a global perspective on medical device regulations - Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards - Includes a useful case study demonstrating the design and approval process

Biosynthetic Polymers for Medical Applications

Biosynthetic Polymers for Medical Applications PDF Author: Laura Poole-Warren
Publisher: Elsevier
ISBN: 1782421130
Category : Technology & Engineering
Languages : en
Pages : 360

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Book Description
Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. - Comprehensively covers all major medical applications of biosynthetic polymers - Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses - Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers