Hyaluronic Acid for Biomedical and Pharmaceutical Applications PDF Download
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Author: Maurice N Collins
Publisher: Smithers Rapra
ISBN: 1909030783
Category : Medical
Languages : en
Pages : 238
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Book Description
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.
Author: Maurice N Collins
Publisher: Smithers Rapra
ISBN: 1909030783
Category : Medical
Languages : en
Pages : 238
Get Book
Book Description
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.
Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0128170565
Category : Business & Economics
Languages : en
Pages : 654
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Book Description
Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field. Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications
Author: Emo Chiellini
Publisher: CRC Press
ISBN: 9780877629290
Category : Technology & Engineering
Languages : en
Pages : 276
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Book Description
The utilization of polymers in medicine has become a reality in the last decade. This book is a concise presentation of the fundamentals, applications, and methods of optimization of polymeric drugs and polymeric drug delivery systems for medicinal purposes. The basic rationale for the use of polymeric drugs and polymer delivery systems is the possibility to alter the pharmacokinetics and pharmacodynamics of therapeutic agents so as to maintain an adequate therapeutic environment at the site of disfunction for an extended period of time. The primary objectives for using polymeric drugs and polymeric drug delivery systems are to introduce new and efficient methods of drug administration, to improve efficacy and patient compliance, to decrease toxicity, and to ensure safety. The following factors influence the design and performance of polymers for medicinal applications: disease, drug properties, type of therapy (acute or chronic), physiology of the patient, administration route, and the site requiring therapy.
Author: Raphael M. Ottenbrite
Publisher: Springer Science & Business Media
ISBN: 144195919X
Category : Technology & Engineering
Languages : en
Pages : 438
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Book Description
Hydrogels are networks of polymer chains which can produce a colloidal gel containing over 99 per cent water. The superabsorbency and permeability of naturally occurring and synthetic hydrogels give this class of materials an amazing array of uses. These uses range from wound dressings and skin grafts to oxygen-permeable contact lenses to biodegradable delivery systems for drugs or pesticides and scaffolds for tissue engineering and regenerative medicine. Biomedical Applications of Hydrogels Handbook provides a comprehensive description of this diverse class of materials, covering both synthesis and properties and a broad range of research and commercial applications. The Handbook is divided into four sections: Stimuli-Sensitive Hydrogels, Hydrogels for Drug Delivery, Hydrogels for Tissue Engineering, and Hydrogels with Unique Properties. Key Features: Provides comprehensive coverage of the basic science and applications of a diverse class of materials Includes both naturally occurring and synthetic hydrogels Edited and written by world leaders in the field.
Author: David Evered
Publisher: John Wiley & Sons
ISBN: 0470513780
Category : Science
Languages : en
Pages : 308
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Book Description
Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.
Author: R. H. Marchessault
Publisher:
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 392
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Book Description
Cellulose and starch are dry binders for tablets. They are essential for drug formulation and for slow-release to maintain drug concentration in the blood. Unusual excipient uses are described such as protein separation and purification, gene delivery and iron content in human physiology.
Author: Sabyasachi Maiti
Publisher: Woodhead Publishing
ISBN: 0081025564
Category : Medical
Languages : en
Pages : 526
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Book Description
Functional Polysaccharides for Biomedical Applications examines the fundamentals and properties of these natural materials and their potential biomedical applications. With an emphasis on therapeutic and sensing applications, the book also reviews how polysaccharides can be modified for tissue engineering applications. Sections discuss the basics of polysaccharides, give an overview of the potential applications, look at novel materials and technologies for use in tissue regeneration and therapeutics, and detail current biomedical applications. With a strong focus on materials, engineering and applications, this book is a valuable resource for those with an interest in harnessing the biomedical potential of natural polymers. Describes strategies for developing polysaccharides-based biomedical devices Illustrates concepts and encompasses scope for clinical development Provides advanced and comprehensive information on biomedical constructs
Author: Thakur Raghu Raj Singh
Publisher: CRC Press
ISBN: 1351648276
Category : Medical
Languages : en
Pages : 309
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Book Description
Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.
Author: Insup Noh
Publisher: Royal Society of Chemistry
ISBN: 1788018834
Category : Technology & Engineering
Languages : en
Pages : 505
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Book Description
Hydrogels represent one of the cornerstones in tissue engineering and regenerative medicine, due to their biocompatibility and physiologically relevant properties. These inherent characteristics mean that they can be widely exploited as bioinks in 3D bioprinting for tissue engineering applications as well as injectable gels for cell therapy and drug delivery purposes. The research in these fields is booming and this book provides the reader with a terrific introduction to the burgeoning field of injectable hydrogel design, bioprinting and tissue engineering. Edited by three leaders in the field, users of this book will learn about different classes of hydrogels, properties and synthesis strategies to produce bioinks. A section devoted to the key processing and design challenges at the hydrogel/3D bioprinting/tissue interface is also covered. The final section of the book closes with pertinent clinical applications. Tightly edited, the reader will find this book to be a coherent resource to learn from. It will appeal to those working across biomaterials science, chemical and biomedical engineering, tissue engineering and regenerative medicine.
Author: Riia Rautiola
Publisher:
ISBN: 9781536170597
Category : Hyaluronic acid
Languages : en
Pages : 128
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Book Description
Hyaluronic acid, or hyaluronan, is a water soluble, anionic extracellular matrix glycosaminoglycan polymer with variable molecular weight that determines its physiological role, rheological properties and applications. Since its discovery in the early 1930s, there has been an increased awareness concerning the biology of hyaluronic acid, its signaling pathways and its role in the biomedical and cosmeceutical industry. Being an endogenous molecule, hyaluronic acid is biocompatible, biodegradable, and has strong mucoadhesive, viscoelastic properties. The authors provide chemical modification approaches to hyaluronic acid, as well as address the magnitude of applications of hyaluronic acid-based targeted drug vectors and patents. The closing study discusses glycosaminoglycans, a specialized group of unbranched, anionic disaccharide polymers attached by a covalent linkage to the membrane proteins via sulphate groups in their sugar moieties.
