Health Outcomes Assessment for Children and Adolescents with Bipolar Disorder Treated with and Without Atypical Antipsychotics PDF Download
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Author: Yonghua Jing
Publisher:
ISBN:
Category :
Languages : en
Pages : 165
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Book Description
Background: Pediatric bipolar disorder (PBD) is a severe, chronic illness and it is a significant cause of suffering and disability. Atypical antipsychotics are commonly used to treat PBD, but the economic and health outcomes of atypical antipsychotic treatment have been extraordinarily understudied. Major objectives for this dissertation are to evaluate the evolving pattern of drug utilization in children and adolescents with bipolar disorder (BD) and to assess the difference in health care utilization and costs between children and adolescents treated with and without atypical antipsychotics. Methods: The study design was a retrospective cohort data analysis of the PharMetrics, a large longitudinal national managed care claims database from 1998 to 2002. The study population included 19,325 youths (7̲age̲18) with a bipolar diagnosis indicated by ICD9 codes. Of those, a total of 488 patients who received atypical antipsychotic (ATYP) monotherapy treatment, 1784 patients who received mood stabilizer (MS) monotherapy treatment, and 1182 patients who received atypical antipsychotic-mood stabilizer (ATYP-MS) combination therapy were identified. Propensity scores were used to control for the selection bias inherent in drug treatment selection. Six months of follow-up health care utilization and costs data were compared between propensity-score matched groups using paired t-tests. Results: The prevalence of atypical antipsychotic use increased from 13.23 prescriptions per 100 recipients per quarter to 63.12 prescriptions per 100 recipients per quarter during the study period. Compare to MS monotherapy subjects, ATYP monotherapy subjects had fewer bipolar-related physician office visits (p=0.0093) and bipolar-related outpatient hospitalization visits (p=0.034) but similar bipolar-related days of hospitalization (p=0.24), and bipolar-related emergency department visits (p=0.23). ATYP-MS combination therapy subjects had more health utilization like bipolar-related physician office visits (p
Author: Yonghua Jing
Publisher:
ISBN:
Category :
Languages : en
Pages : 165
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Book Description
Background: Pediatric bipolar disorder (PBD) is a severe, chronic illness and it is a significant cause of suffering and disability. Atypical antipsychotics are commonly used to treat PBD, but the economic and health outcomes of atypical antipsychotic treatment have been extraordinarily understudied. Major objectives for this dissertation are to evaluate the evolving pattern of drug utilization in children and adolescents with bipolar disorder (BD) and to assess the difference in health care utilization and costs between children and adolescents treated with and without atypical antipsychotics. Methods: The study design was a retrospective cohort data analysis of the PharMetrics, a large longitudinal national managed care claims database from 1998 to 2002. The study population included 19,325 youths (7̲age̲18) with a bipolar diagnosis indicated by ICD9 codes. Of those, a total of 488 patients who received atypical antipsychotic (ATYP) monotherapy treatment, 1784 patients who received mood stabilizer (MS) monotherapy treatment, and 1182 patients who received atypical antipsychotic-mood stabilizer (ATYP-MS) combination therapy were identified. Propensity scores were used to control for the selection bias inherent in drug treatment selection. Six months of follow-up health care utilization and costs data were compared between propensity-score matched groups using paired t-tests. Results: The prevalence of atypical antipsychotic use increased from 13.23 prescriptions per 100 recipients per quarter to 63.12 prescriptions per 100 recipients per quarter during the study period. Compare to MS monotherapy subjects, ATYP monotherapy subjects had fewer bipolar-related physician office visits (p=0.0093) and bipolar-related outpatient hospitalization visits (p=0.034) but similar bipolar-related days of hospitalization (p=0.24), and bipolar-related emergency department visits (p=0.23). ATYP-MS combination therapy subjects had more health utilization like bipolar-related physician office visits (p
Author: Barbara Geller
Publisher: Guilford Press
ISBN: 1593856784
Category : Psychology
Languages : en
Pages : 433
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Book Description
Recent advances in evidence-based treatment of pediatric bipolar disorder are reviewed in this authoritative volume. The editors and contributors examine the current status of medications and psychosocial therapies, and explore new horizons in tailoring treatment to individuals' neurobiological and clinical profiles.
Author: Robert L. Findling
Publisher: CRC Press
ISBN: 9781841840543
Category : Medical
Languages : en
Pages : 180
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Book Description
Bipolar disorders were once considered rare in children and adolescents. A growing body of scientific evidence now suggests that they may be more prevalent in this group than previously believed. At the same time, the practitioner faces significant clinical challenges in both the assessment processes and also the implementation of a treatment plan. A paucity of treatment manuals and pharmacological algorithms providing practical guidance makes the task of the clinician even more difficult, despite the fact that more is known about the assessment, neurobiology and treatment of children and adolescents with bipolar disorder than ever before. Written by three distinguished experts, this book conveys to clinicians all the information currently available in this area. They review both the neuroscience and also the integration of rational, practical, pharmacological and psychosocial interventions. Based on what is known, a sound approach to the assessment of these youngsters can be developed. Similarly, available evidence allows practitioners to ground their treatment protocols solidly on scientific knowledge. Concise and authoritative, Pediatric Bipolar Disorders will give the reader a practical approach to both the art and science of providing the best possible clinical care to children and adolescents with the disorder. This book is written primarily for clinical psychiatrists, but will also be of interest to non-specialist doctors and other members of the health care team.
Author: Rasim Somer Diler
Publisher: Nova Publishers
ISBN: 9781594549816
Category : Medical
Languages : en
Pages : 248
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Book Description
Despite the fact that much evidence exists to prove that bipolar disorder effects a large amount of children, during the past century doctors have been very reluctant to diagnose bipolar disorder (BPD) before adulthood. In contemporary times, the bias against diagnosing bipolar disorder in youth has been perpetuated by the lack of agreed upon diagnostic criteria that accurately characterise the condition as it typically exists in childhood. As observed by a number of contributors to this volume, this bias extended to birth cohort studies around the world in that instruments designed to detect mania or bipolar disorder were almost never or rarely applied. In the US, the continued use of unmodified DSM-IV criteria to diagnose prepubertal-onset BPD has only recently been tempered by the knowledge that these criteria were developed based solely on observations in adult studies. While the diagnosis of bipolar disorder in childhood still remains the subject of some controversy, today, thankfully, the controversy has shifted from a debate about whether it can be diagnosed to how it is diagnosed. There is now a general consensus among clinicians and researchers all over the world that bipolar disorder does exist in youth and is associated with significant morbidity and mortality; however, the developmental continuity of prepubertal mania with adult bipolar disorder remains yet undetermined and we know very little and are still in great need to learn more about epidemiology, etiology, phenomenology, and treatment of this condition., This book aims to give the first glimpse of the current state of knowledge about paediatric bipolar disorder from around the world and provides an in-depth view of both the differences and the similarities in diagnosis, comorbidity, clinical and research concepts and treatment approaches of colleagues from different parts of the world as well as serves as a source for the historical development of child and adolescent psychiatry, and for the epidemiology of some frequently seen childhood disorders in various countries.
Author: Robert A. Kowatch
Publisher: American Psychiatric Pub
ISBN: 1585629022
Category : Medical
Languages : en
Pages : 358
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Book Description
Clinical Manual for Management of Bipolar Disorder in Children and Adolescents was written in response to the growing body of knowledge surrounding pediatric bipolar illness and the underlying biological, environmental, and psychosocial influences that exacerbate symptoms and behavior. Written to provide clinically useful information about diagnosis and management, this manual is a comprehensive collection of empirical evidence, case studies, and the growing number of evidence-based reports on pediatric bipolar disorder over the past five years. This manual also contains several chapters provided by Dr. Mary Fristad and her team at The Ohio State University -- experts in family and psychosocial aspects of pediatric bipolar disorder. Her contributions, along with vast clinical evidence and the expertise provided by Drs. Kowatch, Findling, and Post, help paint an accurate picture of everything from age onset to the effectiveness of various therapies. In this manual, clinicians can refer to the following tools: A clinical description of childhood and adolescent bipolar disorder Management strategies for the patient including daily mood charting Current medication strategies and tactics Ways to help patients through the educational system Resources for clinicians, parents and patients A review of the future directions for childhood and adolescent bipolar disorder The many new developments in the field of pediatric bipolar disorder are affirming what this manual emphasizes -- that a combination of family and cognitive-behavior therapy can work in tandem with medical treatments to help young bipolar disorder patients achieve a more balanced life and a greater chance of controlling this illness later in life. The manual demonstrates how the medical community has shifted from asking, "Does bipolar disorder really exist in children and adolescents" to "How can we best predict, diagnose and treat this serious medical disorder" through a review of 25 years of study and insight.
Author: Hans Steiner
Publisher: John Wiley & Sons
ISBN: 1118961706
Category : Psychology
Languages : en
Pages : 496
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Book Description
A unique guide to adolescent psychopathology, using a developmental approach Treating Adolescents is a comprehensive guide to adolescent mental health care, synthesizing evidence-based practice and practice-based perspectives to give providers the best advice available. By limiting the discussion to disorders which appear during adolescence, this useful manual can delve more deeply into each to present extensive evidence and practice-based rationales for approaching a range of psychopathologies. This edition has been revised to reflect the changes in the DSM-5 and the ICD-10, with entirely new chapters on ADHD, learning and executive function, bipolar and mood disorders, sleep disorders, and suicide and self-injury. Coverage includes non-therapy interventions, such as pharmacological and environmental. The discussion of schizophrenia and psychotic disorders includes adolescent presentations of Pervasive Developmental Disorders and their relationship to classical schizophrenia. In a developmental approach to adolescent psychopathology, different treatments are carefully integrated and matched to pathogenic processes in an effort to disrupt causal loops. This book provides in-depth guidance for providers seeking well-rounded treatment plans, with detailed explanations and expert insight. Understand disruptive behaviors and ADHD more deeply Treat anxiety, depression, and mood disorders more effectively Handle psychiatric traumas and related psychopathologies Delve into substance abuse, self-harm, eating disorders, and more Current scholarship favors developmental approaches to psychopathology and supports an emphasis on integrated treatment packages, including environmental, biologic, and psychological interventions. With full integration of practice and research, Treating Adolescents is a comprehensive reference for constructing a complete treatment strategy.
Author: Harsh K. Trivedi
Publisher: Elsevier Health Sciences
ISBN: 1455747432
Category : Medical
Languages : en
Pages : 310
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Book Description
Psychopharmacology is a dominant treatment in child and adolescent psychiatry with proven benefits to young patients. The authors present topics related to PSYCHOPHARMACOLOGY ISSUES: Ethical issues, Treatment planning, Side effects, Neural correlates, and Pharmacogenomics. They address DRUGS FOR SPECIFIC DISEASES: Anxiety, Depression, Eating disorders, Sleep disorders, Psychosis and Schizophrenia, High-risk for bilpolar and schizophrenia, Bipolar, ADHD, and Autism. Each topic presents an Overview of the Disease or Issue, Empirical evidence for ethical issues, Treatment summaries that include dose ranges, side effects, contraindications, and how the drugs are used specifically for a disorder. Treatment in the presence of co-morbid conditions, Long-term evidence, and Conclusions and Future directions complete the presentations. Clinical vignettes are provided that exemplify the main points of the topic.
Author: Demitri Papolos
Publisher: Random House LLC
ISBN: 0767928601
Category : Medical
Languages : en
Pages : 474
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Book Description
A revised edition of this important study discusses the diagnosis and treatment of early onset bipolar disorder in children, arguing that many youngsters who are currently being treated for ADHD and depression may be suffering from the early stages of manic depression, offering new information on mood-stabilizing drugs, omega-3 fatty acids, educational opportunities, and more. Reprint. 50,000 first printing.
Author: Sonam Mehta
Publisher:
ISBN:
Category : Manic-depressive illness in children
Languages : en
Pages : 132
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Book Description
Author: Sics Editore
Publisher: SICS Editore
ISBN: 8869307174
Category : Medical
Languages : en
Pages : 42
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Book Description
The main aim of therapy is acute treatment and prevention of recurrences of manic and depressive episodes. Always assess, if a depressive patient has earlier had periods of mania or hypomania, i.e., if he/she has a bipolar disorder. Acute phases of a bipolar disorder are usually treated in psychiatric hospitals. Arrange for the immediate hospitalization of a manic patient.
