Genetic Barriers to the Heterologous Gene Expression in Bacillus Subtilis

Genetic Barriers to the Heterologous Gene Expression in Bacillus Subtilis PDF Author: Chih-Kai Lin
Publisher:
ISBN:
Category :
Languages : en
Pages : 228

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Genetic Barriers to the Heterologous Gene Expression in Bacillus Subtilis

Genetic Barriers to the Heterologous Gene Expression in Bacillus Subtilis PDF Author: Chih-Kai Lin
Publisher:
ISBN:
Category :
Languages : en
Pages : 228

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Book Description


Prokaryotic Cytoskeletons

Prokaryotic Cytoskeletons PDF Author: Jan Löwe
Publisher: Springer
ISBN: 331953047X
Category : Science
Languages : en
Pages : 457

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Book Description
This book describes the structures and functions of active protein filaments, found in bacteria and archaea, and now known to perform crucial roles in cell division and intra-cellular motility, as well as being essential for controlling cell shape and growth. These roles are possible because the cytoskeletal and cytomotive filaments provide long range order from small subunits. Studies of these filaments are therefore of central importance to understanding prokaryotic cell biology. The wide variation in subunit and polymer structure and its relationship with the range of functions also provide important insights into cell evolution, including the emergence of eukaryotic cells. Individual chapters, written by leading researchers, review the great advances made in the past 20-25 years, and still ongoing, to discover the architectures, dynamics and roles of filaments found in relevant model organisms. Others describe one of the families of dynamic filaments found in many species. The most common types of filament are deeply related to eukaryotic cytoskeletal proteins, notably actin and tubulin that polymerise and depolymerise under the control of nucleotide hydrolysis. Related systems are found to perform a variety of roles, depending on the organisms. Surprisingly, prokaryotes all lack the molecular motors associated with eukaryotic F-actin and microtubules. Archaea, but not bacteria, also have active filaments related to the eukaryotic ESCRT system. Non-dynamic fibres, including intermediate filament-like structures, are known to occur in some bacteria.. Details of known filament structures are discussed and related to what has been established about their molecular mechanisms, including current controversies. The final chapter covers the use of some of these dynamic filaments in Systems Biology research. The level of information in all chapters is suitable both for active researchers and for advanced students in courses involving bacterial or archaeal physiology, molecular microbiology, structural cell biology, molecular motility or evolution. Chapter 3 of this book is open access under a CC BY 4.0 license.

Genetics and Breeding of Industrial Microorganisms

Genetics and Breeding of Industrial Microorganisms PDF Author: Christopher Ball
Publisher: CRC Press
ISBN: 1351080695
Category : Medical
Languages : en
Pages : 210

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Book Description
This text provides a clear exposition of genetic principles and problems with comprehensive, up-to-date references. Specialists who have collaborated closely with industry give an inside authentic view of the genetics and breeding of industrial microorganisms such as yeasts, filamentous fungi, actinomycetes, pseudomonads, and other bacteria of major industrial significance. This book will be especially valuable to many professionals in the field of microbial genetics.

Encyclopedia of Neuroscience

Encyclopedia of Neuroscience PDF Author: Marc D. Binder
Publisher: Springer
ISBN: 9783540237358
Category : Medical
Languages : en
Pages : 4398

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Book Description
This 5000-page masterwork is literally the last word on the topic and will be an essential resource for many. Unique in its breadth and detail, this encyclopedia offers a comprehensive and highly readable guide to a complex and fast-expanding field. The five-volume reference work gathers more than 10,000 entries, including in-depth essays by internationally known experts, and short keynotes explaining essential terms and phrases. In addition, expert editors contribute detailed introductory chapters to each of 43 topic fields ranging from the fundamentals of neuroscience to fascinating developments in the new, inter-disciplinary fields of Computational Neuroscience and Neurophilosophy. Some 1,000 multi-color illustrations enhance and expand the writings.

Regulation of Gene Expression by Small RNAs

Regulation of Gene Expression by Small RNAs PDF Author: Rajesh K. Gaur
Publisher: CRC Press
ISBN: 1420008706
Category : Science
Languages : en
Pages : 440

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Book Description
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p

Evolutionary Transitions to Multicellular Life

Evolutionary Transitions to Multicellular Life PDF Author: Iñaki Ruiz-Trillo
Publisher: Springer
ISBN: 9401796424
Category : Science
Languages : en
Pages : 489

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Book Description
The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.

The New Science of Metagenomics

The New Science of Metagenomics PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309106761
Category : Science
Languages : en
Pages : 170

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Book Description
Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.

Functional Metagenomics: Tools and Applications

Functional Metagenomics: Tools and Applications PDF Author: Trevor C. Charles
Publisher: Springer
ISBN: 3319615106
Category : Science
Languages : en
Pages : 256

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Book Description
In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.

Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 774

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Book Description


Bacillus Molecular Genetics and Biotechnology Applications

Bacillus Molecular Genetics and Biotechnology Applications PDF Author: A.T. Ganesan
Publisher: Academic Press
ISBN: 0323138632
Category : Nature
Languages : en
Pages : 511

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Book Description
Bacillus Molecular Genetics and Biotechnology Applications contains the proceedings of the Third International Conference on the Genetics and Biotechnology of Bacilli, held at Stanford University in Stanford, California on July 15-17, 1985. Contributors discuss the progress that has been made concerning the molecular genetics and biotechnology of Bacillus and cover topics related to transposons and plasmids, secretion, gene cloning, and gene expression. This volume is organized into five sections encompassing 39 chapters and begins with an overview of the origin and the state of molecular genetics, along with some of the contributions microbiology has made to fundamental biology. It then emphasizes the importance of scientifically based regulatory decisions and responsible industry actions for effective biotechnology regulation. The chapters that follow focus on Bacillus subtilis, touching on topics such as DNA recombination in plasmids, genetic system for stabilizing cloned genes, regulation of sporulation, and non-complementing diploids. The reader is methodically introduced to the secretion and maturation of subtilisin, cloning in streptomycetes, and genetic exchange and prospects for cloning in Clostridia. The book concludes with a chapter that describes an integrative and amplifiable secretion vector using the inducible promoter and signal peptide from the B. subtilis levansucrase (LS) gene. This book will be of interest to geneticists, microbiologists, and biotechnologists, as well as students and researchers in the fields of molecular biology and biochemistry.