Breast Cancer Metastasis and Drug Resistance

Breast Cancer Metastasis and Drug Resistance PDF Author: Aamir Ahmad
Publisher: Springer Nature
ISBN: 3030203018
Category : Medical
Languages : en
Pages : 432

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Book Description
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Breast Cancer Metastasis and Drug Resistance

Breast Cancer Metastasis and Drug Resistance PDF Author: Aamir Ahmad
Publisher: Springer Nature
ISBN: 3030203018
Category : Medical
Languages : en
Pages : 432

Get Book Here

Book Description
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Black Families in White America

Black Families in White America PDF Author: Andrew Billingsley
Publisher: Englewood Cliffs, N.J. : Prentice-Hall
ISBN:
Category : African American children
Languages : en
Pages : 238

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Book Description


Journsl

Journsl PDF Author: Independently Published
Publisher:
ISBN:
Category :
Languages : en
Pages : 120

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Book Description
6x9/BlackLined/White/120pages A Journal for you to write down your heart's contents, to take notes, practice your creative writing, write down your to-do-lists or simply enjoy journaling.

Saving Women's Lives

Saving Women's Lives PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309165946
Category : Medical
Languages : en
Pages : 384

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Book Description
The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented.

Advancing the Science of Cancer in Latinos

Advancing the Science of Cancer in Latinos PDF Author: Amelie G. Ramirez
Publisher: Springer Nature
ISBN: 303029286X
Category : Medical
Languages : en
Pages : 320

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Book Description
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

Absolute Risk

Absolute Risk PDF Author: Ruth M. Pfeiffer
Publisher: CRC Press
ISBN: 1466561688
Category : Mathematics
Languages : en
Pages : 201

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Book Description
Absolute Risk: Methods and Applications in Clinical Management and Public Health provides theory and examples to demonstrate the importance of absolute risk in counseling patients, devising public health strategies, and clinical management. The book provides sufficient technical detail to allow statisticians, epidemiologists, and clinicians to build, test, and apply models of absolute risk. Features: Provides theoretical basis for modeling absolute risk, including competing risks and cause-specific and cumulative incidence regression Discusses various sampling designs for estimating absolute risk and criteria to evaluate models Provides details on statistical inference for the various sampling designs Discusses criteria for evaluating risk models and comparing risk models, including both general criteria and problem-specific expected losses in well-defined clinical and public health applications Describes many applications encompassing both disease prevention and prognosis, and ranging from counseling individual patients, to clinical decision making, to assessing the impact of risk-based public health strategies Discusses model updating, family-based designs, dynamic projections, and other topics Ruth M. Pfeiffer is a mathematical statistician and Fellow of the American Statistical Association, with interests in risk modeling, dimension reduction, and applications in epidemiology. She developed absolute risk models for breast cancer, colon cancer, melanoma, and second primary thyroid cancer following a childhood cancer diagnosis. Mitchell H. Gail developed the widely used "Gail model" for projecting the absolute risk of invasive breast cancer. He is a medical statistician with interests in statistical methods and applications in epidemiology and molecular medicine. He is a member of the National Academy of Medicine and former President of the American Statistical Association. Both are Senior Investigators in the Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health.

Invisible Visits

Invisible Visits PDF Author: Tina K. Sacks
Publisher:
ISBN: 019084020X
Category : Medical
Languages : en
Pages : 161

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Book Description
Invisible Visits analyzes why Black middle-class women continue to face inequities in securing fair, equitable, and high-quality healthcare. Unlike other works on health disparities, it integrates social science, public health, and the humanities to better understand why Black women do not receive a proper standard of care at the doctor.

The Black Woman's Guide to Breastfeeding

The Black Woman's Guide to Breastfeeding PDF Author: Kathi Barber
Publisher: Sourcebooks, Inc.
ISBN: 9781402203459
Category : African American mothers
Languages : en
Pages : 0

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Book Description
This timely, up-to-date guide addresses the unique economic and social issues of black women while showing them why and how to breastfeed their children. African American infants are twice as likely to die before their first birthdays as white infants, have the highest rate of asthma of any race and have a 35 percent higher prevalence of childhood obesity than white children. African American women are 2.2 times more likely to die from breast cancer and 30 percent more likely to die from ovarian cancer than white women. All of these health crises can be remedied to some degree with breastfeeding, but virtually all breastfeeding literature on the market fails to speak to the financial, educational and cultural realities of many African American women. The Black Woman's Guide to Breastfeeding addresses the importance of breastfeeding in the African American community and provides all the practical advice African American mothers need to succeed at breastfeeding.

The Cancer Atlas

The Cancer Atlas PDF Author: Ahmedin Jemal
Publisher:
ISBN: 9781604432282
Category : Cancer
Languages : en
Pages : 0

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Book Description
This atlas illustrates the latest available data on the cancer epidemic, showing causes, stages of development, and prevalence rates of different types of cancers by gender, income group, and region. It also examines the cost of the disease, both in terms of health care and commercial interests, and the steps being taken to curb the epidemic, from research and screening to cancer management programs and health education.

Geospatial Approaches to Energy Balance and Breast Cancer

Geospatial Approaches to Energy Balance and Breast Cancer PDF Author: David Berrigan
Publisher: Springer
ISBN: 9783030184100
Category : Medical
Languages : en
Pages : 440

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Book Description
Cancer occurs in specific places and spaces, each of which have identifiable geographic coordinates, characterized by unique natural, built and social characteristics, all of which contribute significantly to cancer across the spectrum from etiology through diagnosis, treatment and outcomes. In the first volume of this series, published in 2010, a single chapter was focused on these geographic influences. Since then, the field of geospatial studies of cancer prevention and control has exploded in approaches and applications. Accordingly, this volume focuses on what has now become a very specific research endeavor, Geospatial Factors Impacting Breast Cancer. The book provides important insights into this relatively new and rapidly developing field. It should be of value to all students of the Energy Balance & Cancer Series and a wide-ranging introduction to problems in cancer prevention and control for geographers, demographers and other researchers with a geospatial perspective. Moreover, it provides important information for all oncologists, endocrinologists, and behavioral modification professionals to better understand their patients in the context of their environment. It should also provide important considerations for physicians, scientists, public health professionals and disparity investigator planning clinical trials, community interventions and community planning.