Zebrafish for Testing Endocrine Disrupting Chemicals

Zebrafish for Testing Endocrine Disrupting Chemicals PDF Author:
Publisher: Nordic Council of Ministers
ISBN: 9789289304801
Category : Zebra danio
Languages : en
Pages : 72

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Zebrafish for Testing Endocrine Disrupting Chemicals

Zebrafish for Testing Endocrine Disrupting Chemicals PDF Author:
Publisher: Nordic Council of Ministers
ISBN: 9789289304801
Category : Zebra danio
Languages : en
Pages : 72

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Book Description


Suitability of Zebrafish as Test Organism for Detection of Endocrine Disrupting Chemicals

Suitability of Zebrafish as Test Organism for Detection of Endocrine Disrupting Chemicals PDF Author: Gitte I. Petersen
Publisher: Nordic Council of Ministers
ISBN: 9789289307215
Category : Endocrine disrupting chemicals
Languages : en
Pages : 70

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A Class Approach to Hazard Assessment of Organohalogen Flame Retardants

A Class Approach to Hazard Assessment of Organohalogen Flame Retardants PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309491215
Category : Political Science
Languages : en
Pages : 103

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Book Description
In the 1970s, flame retardants began to be added to synthetic materials to meet strict flammability standards. Over the years, diverse flame retardants have been manufactured and used in various products. Some flame retardants have migrated out of the products, and this has led to widespread human exposure and environmental contamination. There also is mounting evidence that many flame retardants are associated with adverse human health effects. As a result, some flame retardants have been banned, restricted, or voluntarily phased out of production and use. This publication develops a scientifically based scoping plan to assess additive, nonpolymeric organohalogen flame retardants as a class for potential chronic health hazards under the Federal Hazardous Substances Act, including cancer, birth defects, and gene mutations.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 220: Enchytraeid Reproduction Test

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 220: Enchytraeid Reproduction Test PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264264477
Category :
Languages : en
Pages : 24

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Book Description
This Test Guideline is designed to be used for assessing the effects of chemicals on the reproductive output of the enchytraeid worm, Enchytraeus albidus Henle 1873, in soil.

Zebrafish Protocols for Neurobehavioral Research

Zebrafish Protocols for Neurobehavioral Research PDF Author: Allan V. Kalueff
Publisher: Humana Press
ISBN: 9781617795961
Category : Medical
Languages : en
Pages : 0

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Book Description
Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

Mixture Toxicity

Mixture Toxicity PDF Author: Cornelis A. M. van Gestel
Publisher: CRC Press
ISBN: 1439830096
Category : Medical
Languages : en
Pages : 312

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Book Description
In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an

Short-term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms

Short-term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms PDF Author:
Publisher:
ISBN:
Category : Effluent quality
Languages : en
Pages : 380

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Hormonally Active Agents in the Environment

Hormonally Active Agents in the Environment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309064198
Category : Science
Languages : en
Pages : 453

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Book Description
Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

Development of Ecotoxicity and Toxicity Testing of Chemicals

Development of Ecotoxicity and Toxicity Testing of Chemicals PDF Author:
Publisher: Nordic Council of Ministers
ISBN: 9789289305884
Category : Pesticides
Languages : en
Pages : 126

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OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264079157
Category :
Languages : en
Pages : 170

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Book Description
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.