Author: National Research Council
Publisher: National Academies Press
ISBN: 0309168708
Category : Nature
Languages : en
Pages : 229
Book Description
This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3
Toxicologic Assessment of Jet-Propulsion Fuel 8
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309168708
Category : Nature
Languages : en
Pages : 229
Book Description
This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3
Publisher: National Academies Press
ISBN: 0309168708
Category : Nature
Languages : en
Pages : 229
Book Description
This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3
Acute Exposure Guideline Levels for Selected Airborne Chemicals
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309219876
Category : Nature
Languages : en
Pages : 322
Book Description
Extremely hazardous substances (EHSs)² can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. Acute Exposure Guideline Levels for Selected Airborne Chemicals is the tenth volume of the series and documents for N,N-dimethylformamide, jet propellant fuels 5 and 8, methyl ethyl ketone, perchloromethyl mercaptan, phosphorus oxychloride, phosphorus trichloride, and sulfuryl chloride.
Publisher: National Academies Press
ISBN: 0309219876
Category : Nature
Languages : en
Pages : 322
Book Description
Extremely hazardous substances (EHSs)² can be released accidentally as a result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. Acute Exposure Guideline Levels for Selected Airborne Chemicals is the tenth volume of the series and documents for N,N-dimethylformamide, jet propellant fuels 5 and 8, methyl ethyl ketone, perchloromethyl mercaptan, phosphorus oxychloride, phosphorus trichloride, and sulfuryl chloride.
Jet Fuel Toxicology
Author: Mark L. Witten
Publisher: CRC Press
ISBN: 1439857725
Category : Medical
Languages : en
Pages : 340
Book Description
Currently serving as a resource for the National Center for Toxological Research in their work with the Gulf Coast oil spill, this book presents current research conducted primarily by the airforce on the toxic effects of JP-8 jet fuel on the pulmonary, immune, dermal, and nervous systems. In all, the book considers 13 toxicology studies
Publisher: CRC Press
ISBN: 1439857725
Category : Medical
Languages : en
Pages : 340
Book Description
Currently serving as a resource for the National Center for Toxological Research in their work with the Gulf Coast oil spill, this book presents current research conducted primarily by the airforce on the toxic effects of JP-8 jet fuel on the pulmonary, immune, dermal, and nervous systems. In all, the book considers 13 toxicology studies
Toxicology of the Skin
Author: Nancy A. Monteiro-Riviere
Publisher: CRC Press
ISBN: 1420079182
Category : Medical
Languages : en
Pages : 452
Book Description
This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr
Publisher: CRC Press
ISBN: 1420079182
Category : Medical
Languages : en
Pages : 452
Book Description
This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr
Responding to Oil Spills in the U.S. Arctic Marine Environment
Author: National Research Council
Publisher: National Academies Press
ISBN: 030929889X
Category : Science
Languages : en
Pages : 350
Book Description
U.S. Arctic waters north of the Bering Strait and west of the Canadian border encompass a vast area that is usually ice covered for much of the year, but is increasingly experiencing longer periods and larger areas of open water due to climate change. Sparsely inhabited with a wide variety of ecosystems found nowhere else, this region is vulnerable to damage from human activities. As oil and gas, shipping, and tourism activities increase, the possibilities of an oil spill also increase. How can we best prepare to respond to such an event in this challenging environment? Responding to Oil Spills in the U.S. Arctic Marine Environment reviews the current state of the science regarding oil spill response and environmental assessment in the Arctic region north of the Bering Strait, with emphasis on the potential impacts in U.S. waters. This report describes the unique ecosystems and environment of the Arctic and makes recommendations to provide an effective response effort in these challenging conditions. According to Responding to Oil Spills in the U.S. Arctic Marine Environment, a full range of proven oil spill response technologies is needed in order to minimize the impacts on people and sensitive ecosystems. This report identifies key oil spill research priorities, critical data and monitoring needs, mitigation strategies, and important operational and logistical issues. The Arctic acts as an integrating, regulating, and mediating component of the physical, atmospheric and cryospheric systems that govern life on Earth. Not only does the Arctic serve as regulator of many of the Earth's large-scale systems and processes, but it is also an area where choices made have substantial impact on life and choices everywhere on planet Earth. This report's recommendations will assist environmentalists, industry, state and local policymakers, and anyone interested in the future of this special region to preserve and protect it from damaging oil spills.
Publisher: National Academies Press
ISBN: 030929889X
Category : Science
Languages : en
Pages : 350
Book Description
U.S. Arctic waters north of the Bering Strait and west of the Canadian border encompass a vast area that is usually ice covered for much of the year, but is increasingly experiencing longer periods and larger areas of open water due to climate change. Sparsely inhabited with a wide variety of ecosystems found nowhere else, this region is vulnerable to damage from human activities. As oil and gas, shipping, and tourism activities increase, the possibilities of an oil spill also increase. How can we best prepare to respond to such an event in this challenging environment? Responding to Oil Spills in the U.S. Arctic Marine Environment reviews the current state of the science regarding oil spill response and environmental assessment in the Arctic region north of the Bering Strait, with emphasis on the potential impacts in U.S. waters. This report describes the unique ecosystems and environment of the Arctic and makes recommendations to provide an effective response effort in these challenging conditions. According to Responding to Oil Spills in the U.S. Arctic Marine Environment, a full range of proven oil spill response technologies is needed in order to minimize the impacts on people and sensitive ecosystems. This report identifies key oil spill research priorities, critical data and monitoring needs, mitigation strategies, and important operational and logistical issues. The Arctic acts as an integrating, regulating, and mediating component of the physical, atmospheric and cryospheric systems that govern life on Earth. Not only does the Arctic serve as regulator of many of the Earth's large-scale systems and processes, but it is also an area where choices made have substantial impact on life and choices everywhere on planet Earth. This report's recommendations will assist environmentalists, industry, state and local policymakers, and anyone interested in the future of this special region to preserve and protect it from damaging oil spills.
Immunotoxicology and Immunopharmacology
Author: Robert V. House
Publisher: CRC Press
ISBN: 1420005448
Category : Medical
Languages : en
Pages : 676
Book Description
Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history,
Publisher: CRC Press
ISBN: 1420005448
Category : Medical
Languages : en
Pages : 676
Book Description
Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history,
Long-Term Health Consequences of Exposure to Burn Pits in Iraq and Afghanistan
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030921758X
Category : Medical
Languages : en
Pages : 192
Book Description
Many veterans returning from the conflicts in Iraq and Afghanistan have health problems they believe are related to their exposure to the smoke from the burning of waste in open-air "burn pits" on military bases. Particular controversy surrounds the burn pit used to dispose of solid waste at Joint Base Balad in Iraq, which burned up to 200 tons of waste per day in 2007. The Department of Veterans Affairs asked the IOM to form a committee to determine the long-term health effects from exposure to these burn pits. Insufficient evidence prevented the IOM committee from developing firm conclusions. This report, therefore, recommends that, along with more efficient data-gathering methods, a study be conducted that would evaluate the health status of service members from their time of deployment over many years to determine their incidence of chronic diseases.
Publisher: National Academies Press
ISBN: 030921758X
Category : Medical
Languages : en
Pages : 192
Book Description
Many veterans returning from the conflicts in Iraq and Afghanistan have health problems they believe are related to their exposure to the smoke from the burning of waste in open-air "burn pits" on military bases. Particular controversy surrounds the burn pit used to dispose of solid waste at Joint Base Balad in Iraq, which burned up to 200 tons of waste per day in 2007. The Department of Veterans Affairs asked the IOM to form a committee to determine the long-term health effects from exposure to these burn pits. Insufficient evidence prevented the IOM committee from developing firm conclusions. This report, therefore, recommends that, along with more efficient data-gathering methods, a study be conducted that would evaluate the health status of service members from their time of deployment over many years to determine their incidence of chronic diseases.
Dosage Form Design Considerations
Author:
Publisher: Academic Press
ISBN: 0128144246
Category : Medical
Languages : en
Pages : 881
Book Description
Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design
Publisher: Academic Press
ISBN: 0128144246
Category : Medical
Languages : en
Pages : 881
Book Description
Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. - Examines the history and recent developments in drug dosage forms for pharmaceutical sciences - Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism - Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design
Pulmonary Immunotoxicology
Author: Mitchell D. Cohen
Publisher: Springer Science & Business Media
ISBN: 9780792378433
Category : Medical
Languages : en
Pages : 492
Book Description
A reference for investigators in pulmonary toxicology and immunotoxicology and for people involved in administrating and regulating matters related to inhale materials, and serviceable as a textbook for a graduate or advanced undergraduate course in pulmonary immunotoxicology. US researchers from academic and industrial laboratories provide information concerning the effects of various inhaled materials on the immune system of the respiratory tract. They cover basic background concepts including the normal structure and function of the respiratory system and its basic immunology, the major types of pathological consequences that can arise from immunomodulation within the respiratory tract, the specific major classes of airborne agents that are known to alter immune function, and risk assessment. Annotation copyrighted by Book News, Inc., Portland, OR
Publisher: Springer Science & Business Media
ISBN: 9780792378433
Category : Medical
Languages : en
Pages : 492
Book Description
A reference for investigators in pulmonary toxicology and immunotoxicology and for people involved in administrating and regulating matters related to inhale materials, and serviceable as a textbook for a graduate or advanced undergraduate course in pulmonary immunotoxicology. US researchers from academic and industrial laboratories provide information concerning the effects of various inhaled materials on the immune system of the respiratory tract. They cover basic background concepts including the normal structure and function of the respiratory system and its basic immunology, the major types of pathological consequences that can arise from immunomodulation within the respiratory tract, the specific major classes of airborne agents that are known to alter immune function, and risk assessment. Annotation copyrighted by Book News, Inc., Portland, OR
Gulf War and Health
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165415
Category : Medical
Languages : en
Pages : 516
Book Description
The third in a series of congressionally mandated reports on Gulf War veterans' health, this volume evaluates the long-term, human health effects associated with exposure to selected environmental agents, pollutants, and synthetic chemical compounds believed to have been present during the Gulf War. The committee specifically evaluated the literature on hydrogen sulfide, combustion products, hydrazine and red fuming nitric acid. Both the epidemiologic and toxicologic literature were reviewed.
Publisher: National Academies Press
ISBN: 0309165415
Category : Medical
Languages : en
Pages : 516
Book Description
The third in a series of congressionally mandated reports on Gulf War veterans' health, this volume evaluates the long-term, human health effects associated with exposure to selected environmental agents, pollutants, and synthetic chemical compounds believed to have been present during the Gulf War. The committee specifically evaluated the literature on hydrogen sulfide, combustion products, hydrazine and red fuming nitric acid. Both the epidemiologic and toxicologic literature were reviewed.