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Author: Nick Lane
Publisher:
ISBN: 9781781250372
Category : Cells
Languages : en
Pages : 0
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Book Description
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
Author: Nick Lane
Publisher:
ISBN: 9781781250372
Category : Cells
Languages : en
Pages : 0
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Book Description
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.
Author: Nick Lane
Publisher: OUP Oxford
ISBN: 9780191513015
Category : Science
Languages : en
Pages : 370
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Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford
Author: David Emerald
Publisher:
ISBN: 9780996871839
Category : Business & Economics
Languages : en
Pages : 226
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Book Description
Finalist, 2019 Indie Book Awards, Careers Category Transform Workplace Drama into Workforce Empowerment! If you have ever experienced infighting, such as a team or a department pitting itself against another team or department; if you have ever worked for a micromanaging and overbearing boss; if you have ever navigated the changes that come with a merger or other significant restructuring process, then you have had a front-row seat for organizational drama. 3 Vital Questions is a teaching story about transforming workplace drama and its heavy costs to organizations. Working late at night, Lucas, a middle manager in a large organization, meets a custodian named Ted. The two strike up a friendship as Ted teaches Lucas three vital questions with the power to transform the disillusionment he is experiencing at work. Readers follow Lucas as he learns how to shift from feeling like a Victim to acting as a Creator in his career. With the wise guidance of Ted and Kasey, a senior manager, Lucas applies the three vital questions and begins transforming his workplace relationships, with exciting results. At home, Lucas and his wife Sarah discover how the questions can spark creative collaboration with each other and their two young children. This long-awaited and highly enjoyable read by the author of the bestselling self-leadership title, The Power of TED* (*The Empowerment Dynamic) ushers in a new era of possibility for the world of work. This book teaches David Emerald's groundbreaking 3 Vital Questions(R) approach for empowering leaders and teams to become collaborative, engaged, and resilient in the face of the rapid changes that mark today's increasingly complex competitive environment.
Author: Nick Lane
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353
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Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.
Author: Nick Lane
Publisher: W. W. Norton & Company
ISBN: 0393651495
Category : Science
Languages : en
Pages : 275
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Book Description
From the renowned biochemist and author of The Vital Question, an illuminating inquiry into the Krebs cycle and the origins of life. “Nick Lane’s exploration of the building blocks that underlie life’s big fundamental questions—the origin of life itself, aging, and disease—have shaped my thinking since I first came across his work. He is one of my favorite science writers.”—Bill Gates What brings the Earth to life, and our own lives to an end? For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight —how the same simple chemistry gives rise to life and causes our demise. Lane is among the vanguard of researchers asking why the Krebs cycle, the “perfect circle” at the heart of metabolism, remains so elusive more than eighty years after its discovery. Transformer is Lane’s voyage, as a biochemist, to find the inner meaning of the Krebs cycle—and its reverse—why it is still spinning at the heart of life and death today. Lane reveals the beautiful, violent world within our cells, where hydrogen atoms are stripped from the carbon skeletons of food and fed to the ravenous beast of oxygen. Yet this same cycle, spinning in reverse, also created the chemical building blocks that enabled the emergence of life on our planet. Now it does both. How can the same pathway create and destroy? What might our study of the Krebs cycle teach us about the mysteries of aging and the hardest problem of all, consciousness? Transformer unites the story of our planet with the story of our cells—what makes us the way we are, and how it connects us to the origin of life. Enlivened by Lane’s talent for distilling and humanizing complex research, Transformer offers an essential read for anyone fascinated by biology’s great mysteries. Life is at root a chemical phenomenon: this is its deep logic.
Author: Nick Lane
Publisher: Oxford University Press
ISBN: 0191639079
Category : Science
Languages : en
Pages : 385
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Book Description
Oxygen has had extraordinary effects on life. Three hundred million years ago, in Carboniferous times, dragonflies grew as big as seagulls, with wingspans of nearly a metre. Researchers claim they could have flown only if the air had contained more oxygen than today - probably as much as 35 per cent. Giant spiders, tree-ferns, marine rock formations and fossil charcoals all tell the same story. High oxygen levels may also explain the global firestorm that contributed to the demise of the dinosaurs after the asteroid impact. The strange and profound effects that oxygen has had on the evolution of life pose a riddle, which this book sets out to answer. Oxygen is a toxic gas. Divers breathing pure oxygen at depth suffer from convulsions and lung injury. Fruit flies raised at twice normal atmospheric levels of oxygen live half as long as their siblings. Reactive forms of oxygen, known as free radicals, are thought to cause ageing in people. Yet if atmospheric oxygen reached 35 per cent in the Carboniferous, why did it promote exuberant growth, instead of rapid ageing and death? Oxygen takes the reader on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death. The book explains far more than the size of ancient insects: it shows how oxygen underpins the origin of biological complexity, the birth of photosynthesis, the sudden evolution of animals, the need for two sexes, the accelerated ageing of cloned animals like Dolly the sheep, and the surprisingly long lives of bats and birds. Drawing on this grand evolutionary canvas, Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. The result is a captivating vision of contemporary science and a humane synthesis of our place in nature. This remarkable book will redefine the way we think about the world.
Author: Christopher M. Raymond
Publisher: Cambridge University Press
ISBN: 1108856926
Category : Nature
Languages : en
Pages : 513
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Book Description
Global challenges ranging from climate change and ecological regime shifts to refugee crises and post-national territorial claims are rapidly moving ecosystem thresholds and altering the social fabric of societies worldwide. This book addresses the vital question of how to navigate the contested forces of stability and change in a world shaped by multiple interconnected global challenges. It proposes that senses of place is a vital concept for supporting individual and social processes for navigating these contested forces and encourages scholars to rethink how to theorise and conceptualise changes in senses of place in the face of global challenges. It also makes the case that our concepts of sense of place need to be revisited, given that our experiences of place are changing. This book is essential reading for those seeking a new understanding of the multiple and shifting experiences of place.
Author: Sirona Knight
Publisher: Barron's Educational Series
ISBN: 9780764121159
Category : Recincarnation
Languages : en
Pages : 0
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Book Description
In this absorbing new study, the author presents basic concepts that are common to the varied doctrines of reincarnation in diverse cultures and religions.
Author: Karen Glass
Publisher:
ISBN: 9781700769800
Category :
Languages : en
Pages : 186
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Book Description
Charlotte Mason looked at the world and saw that it was governed by universal laws, such as the law of gravity. Then she wondered. What if there were similar laws that governed the way people learn? If we knew what those laws were, we'd be able to pursue education along the most promising lines . She devoted her life to finding the key principles of education and then developing methods to make the most of them. The result is a comprehensive picture of living and learning that breathes life into education at every level--from babyhood to the adult years. It's not a rote system, but a flexible set of ideas that keep education in focus. These principles are for everyone concerned with teaching and learning. They are no more difficult to implement than the principle of gravity which allows you to walk, run, and even--when you know what you are doing--to soar.
Author: Nick Lane
Publisher: W. W. Norton & Company
ISBN: 0393248194
Category : Science
Languages : en
Pages : 505
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Book Description
“One of the deepest, most illuminating books about the history of life to have been published in recent years.” —The Economist The Earth teems with life: in its oceans, forests, skies and cities. Yet there’s a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists. For two and a half billion years, from the very origins of life, single-celled organisms such as bacteria evolved without changing their basic form. Then, on just one occasion in four billion years, they made the jump to complexity. All complex life, from mushrooms to man, shares puzzling features, such as sex, which are unknown in bacteria. How and why did this radical transformation happen? The answer, Lane argues, lies in energy: all life on Earth lives off a voltage with the strength of a lightning bolt. Building on the pillars of evolutionary theory, Lane’s hypothesis draws on cutting-edge research into the link between energy and cell biology, in order to deliver a compelling account of evolution from the very origins of life to the emergence of multicellular organisms, while offering deep insights into our own lives and deaths. Both rigorous and enchanting, The Vital Question provides a solution to life’s vital question: why are we as we are, and indeed, why are we here at all?
