The Clinical Application of Homocysteine

The Clinical Application of Homocysteine PDF Author: Seema Bhargava (Biochemist)
Publisher:
ISBN: 9789811076336
Category : Clinical biochemistry
Languages : en
Pages : 96

Get Book Here

Book Description
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke - conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the 'marker of the millennium') and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.

The Clinical Application of Homocysteine

The Clinical Application of Homocysteine PDF Author: Seema Bhargava (Biochemist)
Publisher:
ISBN: 9789811076336
Category : Clinical biochemistry
Languages : en
Pages : 96

Get Book Here

Book Description
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke - conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the 'marker of the millennium') and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.

The Clinical Application of Homocysteine

The Clinical Application of Homocysteine PDF Author: Seema Bhargava
Publisher: Springer
ISBN: 9811076324
Category : Medical
Languages : en
Pages : 103

Get Book Here

Book Description
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke – conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the ‘marker of the millennium’) and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.

Homocysteine and Vascular Disease

Homocysteine and Vascular Disease PDF Author: K. Robinson
Publisher: Springer Science & Business Media
ISBN: 9780792362487
Category : Medical
Languages : en
Pages : 480

Get Book Here

Book Description
This state-of-the-art review provides an in-depth and critical summary of homocysteine from its molecular basis to clinical relevance and current clinical trials of folic acid and vitamin B6. Written by leading workers in the field, the book provides an authoritative, comprehensive and thoroughly up-to-date overview for scientists and clinicians and any others engaged in the field. It will also be useful to anyone involved in managing vascular patients or cardiac risk factors, as well as biochemists, pharmacologists, general physicians, cardiologists and clinical and basic researchers with an interest in preventive medicine.

Homocysteine in Health and Disease

Homocysteine in Health and Disease PDF Author: Ralph Carmel
Publisher: Cambridge University Press
ISBN: 9780521653190
Category : Medical
Languages : en
Pages : 558

Get Book Here

Book Description
This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.

Laboratory Assessment of Vitamin Status

Laboratory Assessment of Vitamin Status PDF Author: Dominic J. Harrington
Publisher: Academic Press
ISBN: 0128130512
Category : Medical
Languages : en
Pages : 340

Get Book Here

Book Description
Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status Informs laboratories looking for third party providers of specialist investigations Provides an essential overview of reference ranges for each vitamin

Focus on Homocysteine and the Vitamins

Focus on Homocysteine and the Vitamins PDF Author: Christina Bolander-Gouaille
Publisher: Springer Science & Business Media
ISBN: 2817808452
Category : Medical
Languages : en
Pages : 261

Get Book Here

Book Description
During the last 10-12 years, the research on homocysteine has become very active. About 1500 of articles are now published each year on homocysteine and the vitamins involved in its metabolism. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalised by treatment with folate and/or vitamines B12 and B6. Many of these findings therefore directly concern most practitioners. However, if there are good reviews covering single aspects of this research, these are published in specialised journals. The author has realised the difficulties for the practitioner in keeping updated. This second edition has been thoroughly updated and also offers more data on the vitamins. Over 1600 references are made available.

Homocysteine

Homocysteine PDF Author: Jack Challem
Publisher: Keats Publishing
ISBN: 9780879839161
Category : Health & Fitness
Languages : en
Pages : 116

Get Book Here

Book Description


The Homocysteine Revolution

The Homocysteine Revolution PDF Author: Kilmer S. McCully
Publisher: McGraw Hill Professional
ISBN: 9780879839758
Category : Health & Fitness
Languages : en
Pages : 268

Get Book Here

Book Description
More than 30 years ago, a young Harvard pathologist offered the medical community a theory for the cause of one of today's biggest killers-- heart disease. It is called the Homocysteine Theory and is the medical breakthrough that inspired Andrew Weil to label Dr. McCully as a visionary medical pioneer well ahead of his time. This discovery has the potential to save millions, yet ironically destroyed Dr. McCully's medical career. Homocysteine, a byproduct of metabolism, has been discovered to be a better risk indicator of heart disease than high cholesterol. A simple B6 vitamin and folic acid play a major role in controlling homocysteine levels. This proven theory will change the way the medical establishment views and treats heart disease. Today, the medical community is beginning to accept Dr. McCully's findings transforming his story from medical heresy to legitimate medicine. Updated and revised, complete with a new introduction by Walter Wilett, this eye opening book combines Dr. McCully's personal story and scientific philosophy with a fascinating exposition of his discovery and a special program to make use of this information to improve overall health.

Homocysteine Metabolism: From Basic Science to Clinical Medicine

Homocysteine Metabolism: From Basic Science to Clinical Medicine PDF Author: Ian Graham
Publisher: Springer Science & Business Media
ISBN: 1461557712
Category : Medical
Languages : en
Pages : 396

Get Book Here

Book Description
This volume is the first comprehensive treatise on homocysteine to treat the topic from the basic biochemical, metabolic, genetic, and dietary determinants to disease relationships, including concepts of pathogenesis. In addition, the public health implications of these associations are described. To date, evidence strongly supports the hypotheses that Hyperhomocysteinemia is a strong independent determinant of vascular disease and Many cases of hyperhomocysteinemia are amenable to homocysteine-lowering treatment with B-vitamins.£/LIST£ The strength of this evidence is prompting discussion of large-scale homocysteine-lowering interventions. Against this background of growing recognition of the importance of homocysteine as a factor in coronary artery disease, cerebrovascular disease, stroke, and peripheral vascular disease, the editors conceived of a state-of-the-art monograph on homocysteine and its relationships to disease. The contributors would be those scientists who, in fact, had written the history of this field of study over the past third of a century. The editors invited the leading investigators in the world to contribute chapters in their own areas of expertise to this monograph and to deliver those papers at the first International Meeting on Homocysteine in Ireland, which has emerged as an important study center and where the first cases of homocystinuria were reported more than three decades ago.

A New Gas Chromatographic-mass Spectrometric Method for the Determination of Total Plasma Homocysteine and Related Amino Acids

A New Gas Chromatographic-mass Spectrometric Method for the Determination of Total Plasma Homocysteine and Related Amino Acids PDF Author: Joseph Iskendiarso Sigit
Publisher: Cuvillier Verlag
ISBN: 9783898732949
Category :
Languages : en
Pages : 100

Get Book Here

Book Description