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Author: Thomas F.H. Schmidt
Publisher: Springer Science & Business Media
ISBN: 3662027488
Category : Medical
Languages : en
Pages : 401
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Book Description
Although it is widely recognized that there are significant variations in the circulation throughout the 24-hour day, these patterns have often been conceived as nuisance variables rather than functional differences. Responses of the circulation are examined here not as stable phenomena, but as integrated functions highly sensitive to environmental conditions, and driven by internal and external pacesetters. In this volume, cardiologists with a primary interest in hypertension or heart disease, chronobiologists, and psychologists join together for the first time to give the reader the opportunity to learn the extent and clinical significance of these changes from a chronobiological, behavioral and physiological perspective.
Author: Thomas F.H. Schmidt
Publisher: Springer Science & Business Media
ISBN: 3662027488
Category : Medical
Languages : en
Pages : 401
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Book Description
Although it is widely recognized that there are significant variations in the circulation throughout the 24-hour day, these patterns have often been conceived as nuisance variables rather than functional differences. Responses of the circulation are examined here not as stable phenomena, but as integrated functions highly sensitive to environmental conditions, and driven by internal and external pacesetters. In this volume, cardiologists with a primary interest in hypertension or heart disease, chronobiologists, and psychologists join together for the first time to give the reader the opportunity to learn the extent and clinical significance of these changes from a chronobiological, behavioral and physiological perspective.
Author: Thomas F. H. Schmidt
Publisher: Springer Verlag
ISBN: 9780387547763
Category : Science
Languages : en
Pages : 401
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Book Description
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Henry Kenneth Walker
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 1128
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Book Description
A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309157617
Category : Medical
Languages : en
Pages : 483
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Book Description
Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.
Author: André Aubert
Publisher: Springer Science & Business Media
ISBN: 9401108722
Category : Medical
Languages : en
Pages : 441
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Book Description
In 1992, clinical cardiac electrophysiology became a recognized sub-speciality of the American Board of Internal Medicine. The formal recognition of this highly specialized and technical field of medicine represents the culmination of thirty years of remarkable scientific and intellectual discovery. Beginning in the 1950s, cardiologists realized that cardiac arrhythmias were the cause of significant morbidity and the sudden death of at least 350,000 patients every year in the United States alone. At that time the only tools available for analyzing abnormal heart rhythms were the standard EKG machine and careful deductive reasoning. During the early 1960s, cardiac pacemakers reflected the first foray in the electrical therapy of cardiac arrhythmias. Pacemakers were first implanted in order to control syncopal episodes related to bradycardic heart rhythms. Although crude and bulky devices, their utility was immediately obvious to physicians and patients alike. The recognition that electrical signals could be recorded from inside the heart and that the heart's rhythm could be controlled by the application of electrical energy began the era of clinical cardiac electrophysiology which was to follow. In the late 1960s and early 1970s and at the peak of the Vietnam conflict. a group of cardiologists with special training in cardiac electrophysiology were sequestered at the US Public Health Service Hospital at Staten Island.
Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Book Description
Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: M. Di Rienzo
Publisher: IOS Press
ISBN: 9789051991581
Category : Blood pressure
Languages : en
Pages : 340
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Book Description
CHAPTER 17: Respiratory Pattern, Invested Effort, and Variability in Heart Rate and Blood Pressure During the Performance of Mental Tasks -- CHAPTER 18: Power Spectra of Blood Pressure in Normotensive and Spontaneously Hypertensive Rats: Relationship with Sympathetic Cardiovascular Control -- CHAPTER 19: Sympathectomy, Sinoaortic Denervation and Spectral Powers of Blood Pressure and Heart Rate in Lyon Rats -- CHAPTER 20: Heart Rate Variability in Chronic Heart Failure -- CHAPTER 21: Spectral Analysis of Blood Pressure and Heart Rate in Patients with Myocardial Infarction -- CHAPTER 22: Heart Rate Variability and Sudden Death: What's the Connection? -- CHAPTER 23: Power Spectrum Analysis of Heart Rate in Diabetic. Patients: A Marker of Autonomic Dysfunction -- References -- Author Index
Author: Peter H. Redfern
Publisher: Springer Science & Business Media
ISBN: 3662093553
Category : Medical
Languages : en
Pages : 682
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Book Description
Measured by any criteria, research in chronobiology in general and chronopharmacology in particular has expanded rapidly in recent years. This expansion has been paralleled by an increasing recognition by those outside the field of the relevance and significance of recent developments in chronobiology. Advances in two areas have been chiefly responsible. First, application of the full range of modern techniques in behavioral, neurochemical, and molecular biology have greatly improved our understanding of basic clock mechanisms. In several species the genetic basis of the circadian clock is being progressively delineated. A complete picture of the neurochemical and neuroanatomical structure of the mammalian clock is emerging and the complex pattern of control mechanisms involving endogenous clock mechan isms and photic and nonphotic zeitgebers is being built up as a result of behavioral studies. Secondly, in parallel with these exciting developments in basic science, clinical applications are being convincingly demonstrated in the general fields of pharmacology and medicine as well as in specific areas, e.g., jet lag, shiftwork maladaption syndrome, blindness, and cardiovascular system. It is therefore an opportune time to review progress in the field of chronopharmacology and to introduce some of the exciting developments and prospects to a readership beyond the confines of the chronobiological cognoscenti. This volume is therefore aimed primarily at the pharmacologist - whether basic, applied, or clinical-who is not a specialist in chronobiology.
