Author: Jun Qi
Publisher:
ISBN: 9780542922879
Category :
Languages : en
Pages : 114
Book Description
The quartromicins are a group of structurally complex macrocyclic natural products that display activity against herpes simplex virus type 1 (HSV-1), influenza, and HIV. The quartromicins contain four spirotetronate subunits (two endo and two exo spirotetronates) connected in an alternating head to tail manner. While previous synthetic studies in the Roush laboratory have led to the development of an efficient pathway to the endo spirotetronate subunits, the synthesis of the exo spirotetronate subunits has remained much more challenging.
Studies Toward the Total Synthesis of Quartromicin
Author: Jun Qi
Publisher:
ISBN: 9780542922879
Category :
Languages : en
Pages : 114
Book Description
The quartromicins are a group of structurally complex macrocyclic natural products that display activity against herpes simplex virus type 1 (HSV-1), influenza, and HIV. The quartromicins contain four spirotetronate subunits (two endo and two exo spirotetronates) connected in an alternating head to tail manner. While previous synthetic studies in the Roush laboratory have led to the development of an efficient pathway to the endo spirotetronate subunits, the synthesis of the exo spirotetronate subunits has remained much more challenging.
Publisher:
ISBN: 9780542922879
Category :
Languages : en
Pages : 114
Book Description
The quartromicins are a group of structurally complex macrocyclic natural products that display activity against herpes simplex virus type 1 (HSV-1), influenza, and HIV. The quartromicins contain four spirotetronate subunits (two endo and two exo spirotetronates) connected in an alternating head to tail manner. While previous synthetic studies in the Roush laboratory have led to the development of an efficient pathway to the endo spirotetronate subunits, the synthesis of the exo spirotetronate subunits has remained much more challenging.
Studies Toward the Total Synthesis of Quartromicin D3
Author: Roxanne Kay Kunz
Publisher:
ISBN:
Category :
Languages : en
Pages : 272
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 272
Book Description
Studies Toward the Total Synthesis of Dihydroflustramine C and Perophoramidine
Author: Amir Sabahi
Publisher:
ISBN:
Category : Indole
Languages : en
Pages : 536
Book Description
Publisher:
ISBN:
Category : Indole
Languages : en
Pages : 536
Book Description
Dissertation Abstracts International
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 902
Book Description
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 902
Book Description
Studies Toward the Total Synthesis of Discodermolide
Author: Ge Yang
Publisher:
ISBN:
Category :
Languages : en
Pages : 354
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 354
Book Description
American Doctoral Dissertations
Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
Book Description
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
Book Description
Studies Toward the Total Synthesis of Calyculin A
Author: Samuel William Gerritz
Publisher:
ISBN:
Category :
Languages : en
Pages : 376
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 376
Book Description
Studies Toward the Total Synthesis of (")-chartelline C and ( - )-platensimycin
Author: Evan Adam Hecker
Publisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 542
Book Description
Herein is described our work towards the total synthesis of the marine natural product (")-chartelline C and the potent antibiotic ( - )-platensimycin. Part 1 relates the (")-chartelline C project. The first chapter reviews (")-chartelline C's isolation, biogeneity, and previously reported studies relevant to the area. Chapter 2 tells of our contributions including the development of a convergent, regioselective assembly of an indole-imidazole compound en route to the natural product. Chapter 3 includes the experimental details of this work and the characterization of previously unreported compounds. Part 2 recounts the ( - )-platensimycin research project. Chapter 4 discusses the importance of the natural product and the relevant previous research reported. Chapter 5 describes our efforts in this area, culminating in the stereoselective synthesis of an intermediate closely related to a known compound, which was converted to the natural product. Chapter 6 includes the experimental details of this work and the characterization of previously unreported compounds.
Publisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 542
Book Description
Herein is described our work towards the total synthesis of the marine natural product (")-chartelline C and the potent antibiotic ( - )-platensimycin. Part 1 relates the (")-chartelline C project. The first chapter reviews (")-chartelline C's isolation, biogeneity, and previously reported studies relevant to the area. Chapter 2 tells of our contributions including the development of a convergent, regioselective assembly of an indole-imidazole compound en route to the natural product. Chapter 3 includes the experimental details of this work and the characterization of previously unreported compounds. Part 2 recounts the ( - )-platensimycin research project. Chapter 4 discusses the importance of the natural product and the relevant previous research reported. Chapter 5 describes our efforts in this area, culminating in the stereoselective synthesis of an intermediate closely related to a known compound, which was converted to the natural product. Chapter 6 includes the experimental details of this work and the characterization of previously unreported compounds.
I. Total Synthesis of (+)-clavolonine
Author: Jonathan Richard Scheerer
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 412
Book Description
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 412
Book Description
Studies Towards the Total Synthesis of Manzamine-A
Author: Karel M. Brands
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 134
Book Description