Recent Advances in Synthesizing and Utilizing Nitrogen-containing Heterocycles PDF Download
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Author: Hyun-Joon Ha
Publisher: Frontiers Media SA
ISBN: 2832549187
Category : Science
Languages : en
Pages : 101
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Book Description
Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.
Author: Hyun-Joon Ha
Publisher: Frontiers Media SA
ISBN: 2832549187
Category : Science
Languages : en
Pages : 101
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Book Description
Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.
Author: François Jérôme
Publisher: John Wiley & Sons
ISBN: 1119065445
Category : Science
Languages : en
Pages : 183
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Book Description
A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vast potential for new and better products suggested by recent developments in this exciting field, Bio-Based Solvents will be a welcome resource among students and researchers in catalysis, organic synthesis, electrochemistry, and pharmaceuticals, as well as industrial chemists involved in manufacturing processes and formulation, and policy makers.
Author:
Publisher:
ISBN:
Category : Bioactive compounds
Languages : en
Pages :
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Book Description
Author: Parvesh Singh
Publisher: Elsevier
ISBN: 0323914594
Category : Science
Languages : en
Pages : 650
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Book Description
Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry. The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. - Includes a detailed review of recent research on the reactivity, synthesis and applications of pyridines - Features concise accounts of the reactivity, synthetic and optimized protocols - Discusses the medicinal, inorganic and polymer chemistry applications of pyridines
Author: Sreekantha B. Jonnalagadda
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110986159
Category : Science
Languages : en
Pages : 483
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Book Description
The solvent-free approach provides green and alternative synthetic methods for obtaining diverse bioactive heterocycles. The solvent is frequently the primary component of synthetic protocol and contributes to significant waste. Additionally, its removal processes are energy intensive and substantial. This book explores different solvent-free procedures for efficiently synthesising heterocyclic analogues of immense biological importance and other applications.
Author: Navjeet Kaur
Publisher: Elsevier
ISBN: 0443134243
Category : Science
Languages : en
Pages : 442
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Book Description
Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer helps readers quickly assess possible synthetic approaches. The book's audience, researchers, academic professionals and synthetic chemists both in industry and academia will find detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turned out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time, and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical and can play three other roles in organic chemistry, i.e., as stabilizer, reagent and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units. - Includes comprehensive descriptions of heterocycle synthesis - Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide - Helps readers quickly assess possible synthetic approaches
Author: Navjeet Kaur
Publisher: Elsevier
ISBN: 0443132607
Category : Science
Languages : en
Pages : 334
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Book Description
Four-Membered Heterocycle Synthesis offers a comprehensive approach to these unstable organic compounds, providing a systematic introduction to the synthesis and reactions of all common four-membered heterocycles and illustrating different methods to prepare specific four-membered heterocycles. Four-membered heterocyclic compounds are known as a class of unstable organic compounds because of their strain characteristics, which make them very beneficial as precursors for the formation of a broad range of complex heterocyclic molecules and for synthetic elaboration. - Provides a systematic introduction to the synthesis and reactions of all common four-membered heterocycles - Highlights different methods to prepare specific 4-membered heterocycles - Analyzes several types and families of compounds, with a large set of recent examples in the field
Author: Rakesh Kumar Sharma
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110797461
Category : Science
Languages : en
Pages : 606
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Book Description
Carbon-carbon and carbon-heteroatom bond-forming reactions are the backbone of synthetic organic chemistry. Scientists are constantly developing and improving these techniques in order to maximize the diversity of synthetically available molecules. These techniques must be developed in a sustainable manner in order to limit their environmental impact. This book highlights green bond forming reactions for bioactive scaffolds.
Author: Alan R. Katritzky
Publisher: Academic Press
ISBN: 0124202098
Category : Science
Languages : en
Pages : 293
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Book Description
Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. - One of great importance to organic chemists, polymer chemists and many biological scientists - Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties
Author: Navjeet Kaur
Publisher: CRC Press
ISBN: 1000733416
Category : Science
Languages : en
Pages : 404
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Book Description
Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.
