Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Kamal Dua
Publisher: Academic Press
ISBN: 0128208880
Category : Technology & Engineering
Languages : en
Pages : 620
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Book Description
Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)
Author: Alan R. Leff
Publisher: McGraw-Hill Companies
ISBN: 9780070370968
Category : Medical
Languages : en
Pages : 1219
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Book Description
This is a comprehensive resource for pharmacological therapeutics in pulmonary medicine. The scope of the text includes not only all of chest medicine, but the full scope of critical care as it relates to pulmonary disease.
Author:
Publisher: Elsevier
ISBN: 0443188815
Category : Medical
Languages : en
Pages : 336
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Book Description
Pulmonary Pharmacology, Volume 98 provides in-depth reviews on the latest progresses about respiratory drug discovery and development. Topics covered in this volume include corticosteroids, monoclonal antibodies, tyrosine kinase inhibitors and phosphodiesterase inhibitors for the treatments of asthma, COPD or pulmonary fibrosis, with perspective on the development of novel therapeutic strategies such as renin-angiotensin system modulators, mitochondrial function modulators, and non-antibacterial macrolides. Part of the volume is devoted to senotherapy for lung ageing in respiratory diseases, and novel pulmonary delivery technologies, including inhaled biologics. - Provides accurate reviews from leading experts on the topic of pulmonary pharmacology - Each chapter of the volume provides consolidated graphical materials for ease of reading for the audience - Provides the latest insights and future perspectives on the drug discovery and development for respiratory diseases
Author: Domenico Spina
Publisher: Cambridge University Press
ISBN: 9780521773218
Category : Medical
Languages : en
Pages : 622
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Book Description
Respiratory diseases affect millions of people each year and represent a major health burden around the world. This timely reference surveys and evaluates the drug treatments available for the main categories of lung diseases including asthma, tuberculosis, chronic obstructive pulmonary disease, lung cancer, and respiratory infections. The recent re-emergence of tuberculosis and the increase in asthma in certain populations underlines the importance of finding effective new treatments for these diseases. This publication, a comprehensive reference, is one of the first to survey current and novel drug treatments for this group of diseases. It is certain to establish itself as an essential source of reference for respiratory physicians, clinicians and clinical pharmacologists.
Author: Stefano Aliberti
Publisher: European Respiratory Society
ISBN: 1849840849
Category : Medical
Languages : en
Pages : 332
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Book Description
Author: Carl Waldmann
Publisher: Oxford University Press, USA
ISBN: 0199229589
Category : Medical
Languages : en
Pages : 629
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Book Description
The Oxford Desk Reference: Critical Care allows easy access to evidence-based materials on commonly encountered critical care problems for quick consultation to ensure the optimum management of a particular condition. A concise reference book, it collates key recommendations and presents them in an easily accessible and uniform way.
Author: Gernot Rohde
Publisher: European Respiratory Society
ISBN: 1849840377
Category : Respiratory infections
Languages : en
Pages : 200
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Book Description
Pleuropulmonary infections are among the major causes of morbidity and mortality worldwide. This issue of the European Respiratory Monograph considers pleuropulmonary infections from both medical and surgical angles.
Author: Clive P. Page
Publisher: Springer Science & Business Media
ISBN: 364275855X
Category : Medical
Languages : en
Pages : 333
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Book Description
This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma cological intervention. It is hoped this book will be invaluable for research scientists and clinic ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .
Author: James Li
Publisher: CRC Press
ISBN: 9780849337109
Category : Medical
Languages : en
Pages : 432
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Book Description
Standing as the only text focused on the pharmaceutical treatment of asthma, this reference details the pharmacology, mechanisms of action, efficacy, and safety of every drug currently used in the management and care of asthma patients. Internationally renowned authorities cover published practice guidelines, treatment plans, pharmacologic agents, and clinical studies to provide the most authoritative and up-to-date information on the use of medications to control and prevent this common condition. Reviewing the role of pharmacotherapy in the overall management of asthma, this guide: * reviews the pharmacology and clinical use of inhaled corticosteroids, beta adrenergic agonists, leukotriene modifiers, combination products, and many other asthma drugs * provides a practical framework for the optimal pharmacotherapy of asthma, focusing on outpatient therapy * examines international guidelines for the drug treatment of asthma.
