Precision Vaccinology for Infectious Diseases PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Precision Vaccinology for Infectious Diseases PDF full book. Access full book title Precision Vaccinology for Infectious Diseases by Mahbuba Rahman. Download full books in PDF and EPUB format.
Author: Mahbuba Rahman
Publisher: Frontiers Media SA
ISBN: 2832548474
Category : Medical
Languages : en
Pages : 351
Get Book
Book Description
The Human body is a vast network of interacting genes, proteins, and metabolites. These components, which may be considered host factors, change under disease, treatment or healthy condition. While treatment of many diseases depends on therapeutic drugs, vaccines remain the most effective long-term public health intervention to prevent infectious diseases. To date, vaccines have been developed to treat entire populations with little provision for predisposing individual host factor differences. However, the use and application of vaccines is facing multiple challenges with increasing numbers of vaccine non-responders and vaccine-relapsed individuals. The cause of this complication is partially due to host-factors. Another challenge is the adverse effects of vaccines in patients with primary immunodeficiency or autoimmune diseases, as well as vaccine-waning immunity in ageing populations, obese populations, or those with co-infection. To overcome these challenges, the solution may be the design, and formulation of precision vaccines, which are patient-specific.
Author: Mahbuba Rahman
Publisher: Frontiers Media SA
ISBN: 2832548474
Category : Medical
Languages : en
Pages : 351
Get Book
Book Description
The Human body is a vast network of interacting genes, proteins, and metabolites. These components, which may be considered host factors, change under disease, treatment or healthy condition. While treatment of many diseases depends on therapeutic drugs, vaccines remain the most effective long-term public health intervention to prevent infectious diseases. To date, vaccines have been developed to treat entire populations with little provision for predisposing individual host factor differences. However, the use and application of vaccines is facing multiple challenges with increasing numbers of vaccine non-responders and vaccine-relapsed individuals. The cause of this complication is partially due to host-factors. Another challenge is the adverse effects of vaccines in patients with primary immunodeficiency or autoimmune diseases, as well as vaccine-waning immunity in ageing populations, obese populations, or those with co-infection. To overcome these challenges, the solution may be the design, and formulation of precision vaccines, which are patient-specific.
Author: Gregg N. Milligan
Publisher: John Wiley & Sons
ISBN: 0470656166
Category : Medical
Languages : en
Pages : 404
Get Book
Book Description
Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.
Author: Ofer Levy
Publisher: Frontiers Media SA
ISBN: 2889716589
Category : Medical
Languages : en
Pages : 335
Get Book
Book Description
Topic Editor Jay Evans is the co-founder, President and CEO of Inimmune Corporation. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Author: Joo Chuan Tong
Publisher: Elsevier
ISBN: 1908818417
Category : Medical
Languages : en
Pages : 164
Get Book
Book Description
Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309075556
Category : Science
Languages : en
Pages : 118
Get Book
Book Description
This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Author: Alan Walker
Publisher: Springer
ISBN: 9811314179
Category : Family & Relationships
Languages : en
Pages : 337
Get Book
Book Description
This book provides the most comprehensive analysis available of the challenges created by Europe’s ageing population. Grounded in state-of-the-art scientific assessments by leading European researchers, the book is strongly policy focused. Indeed this book contains a detailed account of the policies required across a broad field, from economic sustainability and extending working lives, to healthy ageing, technological innovation, long term care and political citizenship, for the successful adaptation to the challenges of ageing in Europe and globally. It is a policy manifesto to ensure that the future of ageing in Europe is transformed into a highly beneficial one for both citizens and societies.
Author: Daan J. A. Crommelin
Publisher: CRC Press
ISBN: 9780415285018
Category : Medical
Languages : en
Pages : 456
Get Book
Book Description
The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.
Author: American Academy of Pediatrics
Publisher:
ISBN: 9781581103069
Category : Health & Fitness
Languages : en
Pages : 0
Get Book
Book Description
The authoritative guide to the latest pediatric infectious disease information. Developed by the AAP Committee on Infectious Diseases in conjunction with the CDC, the FDA, and other leading institutions with contributions from hundreds of physicians nationwide, the newly revised and updated 2009 Red Book continues the tradition of excellence with the latest findings and clinical guidelines on the manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood conditions.
Author: Sandra W. Roush
Publisher: CreateSpace
ISBN: 9781493733798
Category : Medical
Languages : en
Pages : 472
Get Book
Book Description
The Manual for the Surveillance of Vaccine-Preventable Diseases, updated through 2013, provides current guidelines for those directly involved in surveillance of vaccine-preventable diseases, especially personnel at the local health departments. For each of the vaccine-preventable diseases, this manual includes a chapter describing the importance of rapid case identification; the importance of surveillance; disease reduction goals; case definitions (including clinical description and case classifications); epidemiologically important data to be collected during case investigation; activities for enhancing surveillance; activities for case investigation; and activities for outbreak control. Other chapters include information on surveillance indicators; surveillance data analyses; reporting adverse events following vaccination; and enhancing surveillance. In addition, the manual includes a section reserved for insertion of state-specific guidance for VPD surveillance and extensive appendices. This manual was first developed in 1996 to provide general guidance to state and local health department personnel who are involved in surveillance activities for vaccine-preventable diseases. This manual answers commonly asked questions regarding the surveillance and reporting of vaccine-preventable diseases and provides information on enhancing existing surveillance systems.
Author: Ciro A. de Quadros
Publisher: Pan American Health Org
ISBN: 9275115966
Category : Medical
Languages : en
Pages : 410
Get Book
Book Description
This publication contains a number of papers which consider the public health role of vaccines in improving the health of the world's populations, and looks at the challenges of using immunisation to combat emerging and re-emerging diseases. Issues discussed include the innovative use of vaccines against diseases such as meningococcal infection in Africa, Haemophilus influenza type b, varicella, and hepatitis, efforts to develop a new generation of vaccines against cholera and typhoid, shigella and Helicobacter pylori, as well as developments in the quest for vaccines against tuberculosis, HIV/AIDS, dengue, malaria, and hookworm. It also deals with the use of vaccines to fight bioterrorism attacks; regulatory and safety issues; financing issues, impact of health sector reform and the sustainability of immunisation programmes.
