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Author: Cuno Winkler
Publisher: Springer Science & Business Media
ISBN: 3642709478
Category : Medical
Languages : en
Pages : 425
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Book Description
The introduction of nuclear medicine into oncology dates back to the early 1 940s, when Lawrence reported on the tumor retention of 32P-phosphate, von Hevesy and von Euler soon afterwards published their fundamental work on the metabolism of phosphorus in sarcoma cells, and when almost at the same time Keston and his coworkers de scribed their observation of the accumulation of radioactive iodine in metastases of a thyroid carcinoma. Since that time innumerable publi cations have appeared in oncologic literature which deal with the application of nuclear medical methods in experimental cancer re search and also in the diagnosis and treatment of malignant tumors. The significance of some originally very successfully applied clinical methods naturally has changed over the years. For instance, scin tigraphy became somewhat less important for the purely morpho logic assessment of certain tumors after the introduction of transmis sion computerized tomography and modem sonographic methods into clinical practice. On the other hand, however, it has also been possible to further develop scintigraphy to a decisive extent, both 'with refer ence to the test substances applied and in view of the instrumentation. As far as the scintigraphic equipment is concerned, the introduction of static and sequential digital imaging by means of scintillation camera computer systems in the mid-1960s represents important progress, as does the recent development of emission computerized tomography with single photon and positron emitters.
Author: Cuno Winkler
Publisher: Springer Science & Business Media
ISBN: 3642709478
Category : Medical
Languages : en
Pages : 425
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Book Description
The introduction of nuclear medicine into oncology dates back to the early 1 940s, when Lawrence reported on the tumor retention of 32P-phosphate, von Hevesy and von Euler soon afterwards published their fundamental work on the metabolism of phosphorus in sarcoma cells, and when almost at the same time Keston and his coworkers de scribed their observation of the accumulation of radioactive iodine in metastases of a thyroid carcinoma. Since that time innumerable publi cations have appeared in oncologic literature which deal with the application of nuclear medical methods in experimental cancer re search and also in the diagnosis and treatment of malignant tumors. The significance of some originally very successfully applied clinical methods naturally has changed over the years. For instance, scin tigraphy became somewhat less important for the purely morpho logic assessment of certain tumors after the introduction of transmis sion computerized tomography and modem sonographic methods into clinical practice. On the other hand, however, it has also been possible to further develop scintigraphy to a decisive extent, both 'with refer ence to the test substances applied and in view of the instrumentation. As far as the scintigraphic equipment is concerned, the introduction of static and sequential digital imaging by means of scintillation camera computer systems in the mid-1960s represents important progress, as does the recent development of emission computerized tomography with single photon and positron emitters.
Author: Gang Huang
Publisher: Springer
ISBN: 9811374589
Category : Medical
Languages : en
Pages : 346
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Book Description
This book introduces molecular imaging and Target Therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardial infarction, sentinel lymph node, metastatic bone tumors, liver and gallbladder disease in children are introduced. Finally, the applications of radionuclide 131I on treatments of Graves' disease and differentiated thyroid cancer and metastases are investigated respectively. This book is a useful reference for professionals engaged in nuclear medicine and clinical research, including clinical nuclear medicine physicians, nuclear medicine engineers and nuclear medicine pharmacists.
Author: Cuno Winkler
Publisher: Springer
ISBN: 9783540161646
Category : Medical
Languages : en
Pages : 420
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Book Description
The introduction of nuclear medicine into oncology dates back to the early 1 940s, when Lawrence reported on the tumor retention of 32P-phosphate, von Hevesy and von Euler soon afterwards published their fundamental work on the metabolism of phosphorus in sarcoma cells, and when almost at the same time Keston and his coworkers de scribed their observation of the accumulation of radioactive iodine in metastases of a thyroid carcinoma. Since that time innumerable publi cations have appeared in oncologic literature which deal with the application of nuclear medical methods in experimental cancer re search and also in the diagnosis and treatment of malignant tumors. The significance of some originally very successfully applied clinical methods naturally has changed over the years. For instance, scin tigraphy became somewhat less important for the purely morpho logic assessment of certain tumors after the introduction of transmis sion computerized tomography and modem sonographic methods into clinical practice. On the other hand, however, it has also been possible to further develop scintigraphy to a decisive extent, both 'with refer ence to the test substances applied and in view of the instrumentation. As far as the scintigraphic equipment is concerned, the introduction of static and sequential digital imaging by means of scintillation camera computer systems in the mid-1960s represents important progress, as does the recent development of emission computerized tomography with single photon and positron emitters.
Author: Cuno Winkler
Publisher:
ISBN: 9780387161648
Category :
Languages : en
Pages :
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Book Description
Author: H. William Strauss
Publisher: Springer Science & Business Media
ISBN: 0387488944
Category : Medical
Languages : en
Pages : 873
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Book Description
This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
Author: Cumali Aktolun
Publisher: Springer Science & Business Media
ISBN: 1461440211
Category : Medical
Languages : en
Pages : 445
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Book Description
Nuclear Medicine Therapy presents the state of the art in targeted radionuclide therapy, both in clinical practice and contemporary clinical investigation and trials. With contributions from an internationally-distinguished group of physicians and scientists, the book is devoted entirely to the use of nuclear medicine techniques and technology for therapy of malignant and benign diseases. Individual chapters cover the scientific principles and clinical applications of radionuclide therapy and the state of clinical trials of agents currently under investigation in the therapy of tumors involving virtually every organ system. Due to overlapping interest in techniques, indications, and clinical use, the development of radionuclide therapy attracts considerable input from other medical specialists whose collaboration is essential, including radiation and medical oncologists, hematologists, diagnostic radiologists, hepatologists, endocrinologists, and rheumatologists. And because radionuclide therapy is a rapidly evolving field of nuclear medicine, it is the aim of this volume to appeal to all specialists involved in targeted radionuclide therapy and to contribute to the standardization of the practice globally.
Author: Cumali Aktolun
Publisher: Lippincott Williams & Wilkins
ISBN: 146988349X
Category : Medical
Languages : en
Pages : 1964
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Book Description
Nuclear Oncology a contemporary narrative of the role of nuclear medicine in oncology with an emphasis on SPECT/CT and PET/CT with additional comments when appropriate on the potential application of PET/MR and to a lesser degree, targeted radionuclide therapy. This book focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases. It describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology. The basic science and current research topics of nuclear oncology are addressed in separate chapters. Nuclear medicine has become an essential component to all phases of the management of the patient with a malignant tumor and in some cases, even benign neoplasms. The standard of practice for many tumors requires PET/CT imaging at various stages of diagnosis and management. In addition to clinical applications, ongoing investigational efforts, which more and more involve multi-institutional protocols, are also presented. Features: • Focuses on the use of radionuclides in the diagnosis and treatment of malignant diseases • Emphasizes SPECT/CT and PET/CT with additional emphasis on the potential application of PET/MR • Describes relevant approved and investigational clinical applications, instrumentation & technology, chemistry and practical clinical issues in nuclear oncology
Author: Tod W. Speer
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153260
Category : Medical
Languages : en
Pages : 564
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Book Description
Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309134153
Category : Medical
Languages : en
Pages : 173
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Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Author: Hojjat Ahmadzadehfar
Publisher: Springer Nature
ISBN: 3030394573
Category : Medical
Languages : en
Pages : 1017
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Book Description
In the new edition of this very successful book, European and North American experts present the state of the art in diagnostic and therapeutic radionuclide procedures. The aim is to examine established and emerging clinical applications in detail, rather than to consider everything included in the comprehensive texts already available within the field. This “practical” approach ensures that the book will be a valuable guide for nuclear medicine physicians, technologists, students, and interested clinicians alike. This edition of Clinical Nuclear Medicine has been extensively revised to take account of recent developments. The roles of SPECT/CT, PET/CT, and PET/MRI are clearly explained and illustrated, and the coverage extended to encompass, for example, novel PET tracers and therapeutic radionuclides, advanced techniques of brain imaging, and the development of theranostics. Readers will be fully persuaded of the ever-increasing value of nuclear medicine techniques in depicting physiology and function and complementing anatomic modalities such as CT, MRI, and ultrasound.
