Molecules Of Death (2nd Edition) PDF Download
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Author: Steven C Mitchell
Publisher: World Scientific Publishing Company
ISBN: 1911298445
Category : Medical
Languages : en
Pages : 456
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Book Description
This book has been developed over many years from several popular courses taught to students at both Birmingham and London universities. It provides an important step in introducing principles and concepts within the field of toxicology. The underlying mechanisms of toxicity are highlighted through examples taken from gases, minerals, plants, fungi, bacteria, marine creatures, industrial chemicals and pharmacological agents.In this second edition, the text has been completely revised and expanded with the addition of six new chapters — carbon monoxide, hydrofluoric acid, lead, mushroom, toxins, paracetamol, paraquat and diquat. Each chapter is self-sufficient, enabling readers to dip into chapters of interest at random without any lack of understanding. The book is informative, with numerous clinical details, and will appeal to those who wish to delve into this fascinating subject./a
Author: Waring
Publisher:
ISBN: 9781860948381
Category :
Languages : en
Pages : 455
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Book Description
Author: Steven C Mitchell
Publisher: World Scientific Publishing Company
ISBN: 1911298445
Category : Medical
Languages : en
Pages : 456
Get Book Here
Book Description
This book has been developed over many years from several popular courses taught to students at both Birmingham and London universities. It provides an important step in introducing principles and concepts within the field of toxicology. The underlying mechanisms of toxicity are highlighted through examples taken from gases, minerals, plants, fungi, bacteria, marine creatures, industrial chemicals and pharmacological agents.In this second edition, the text has been completely revised and expanded with the addition of six new chapters — carbon monoxide, hydrofluoric acid, lead, mushroom, toxins, paracetamol, paraquat and diquat. Each chapter is self-sufficient, enabling readers to dip into chapters of interest at random without any lack of understanding. The book is informative, with numerous clinical details, and will appeal to those who wish to delve into this fascinating subject./a
Author: Mariappan Rajan
Publisher: Frontiers Media SA
ISBN: 2832506283
Category : Science
Languages : en
Pages : 305
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Book Description
In tissue engineering, the ultimate goal is to engineer an entire functioning organ that requires building complex structures of different tissue types. A three-dimensional scaffold seeded with desired cell types. In order to resemble the natural formations of the organs, cells have to be correctly located in relation to one another. It has been shown in cocultures that cells have the capability of spontaneous tissue-like organization when seeded into the scaffold. The ideal scaffolds should have an interconnected porous structure, well-designed pore size and adequate porosity to allow cell attachment, proliferation and differentiation. Moreover, effective bioactive agents and nutrient exchange are crucial during new tissue development. Thus the individual organ cell is a specific mechanism for the construction or regeneration of the cells. Artificial scaffolds have been applied and used as supporting structures for cell cultures as well as for the domination of cell growth in the repair of impaired tissues or organs. During the cell regeneration, the scaffold temporarily helps in cell regeneration and gradually biodegrade either in the course of the healing process or after, and a new tissue with a desired shape and properties is produced. The challenge of tissue engineering is to mimic what happens in nature. Attempts are being made to engineer in vitro practically every tissue and organ in the body. Work is proceeding in creating tissue-engineered liver, nerve, kidney, intestine, pancreas, and even heart muscle and valves. In the area of connective tissues, work has been ongoing worldwide for many years in the engineering of tendon, ligament, bone, and cartilage. Recently, the number of reports was succeeded in skin, bladder, airway, and bone, where tissue-engineered constructs have been used successfully in patients. This Research Topic is the collection of body organ regeneration materials and their cell adhesion and migration for the development and regeneration of tissues. Biomimetic materials promise to advance in current understanding of organ regeneration and repair by providing tools to recapitulate and monitor relevant properties of cellular - microenvironment interactions. Although cell adhesion, migration, and development aspects of tissues have shown success in the clinic, better, more intricate models are needed to understand drivers of tissue repair and regeneration fully. Tissue engineering bears tremendous potential toward gaining a complete understanding of the underlying biological and physical mechanisms advancing the treatment of damaged organs. The following Research Topic “Bio-mimetic materials for tissue regenerations” discusses examples of progress toward this objective. • Bio-mimicking scaffold materials for tissue regeneration • Cell adhesion to scaffold materials • Role of materials for the migration of cells • Mechanisms of cell growth for organ development
Author: Andrew W. Saul
Publisher: Turner Publishing Company
ISBN: 1684429048
Category : Health & Fitness
Languages : en
Pages : 343
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Book Description
#1 NEW RELEASE ON AMAZON Second Edition, Revised, Updated, and Expanded Now with 116 new references added to this edition, providing summary of the very latest niacin research Discover the newest cutting-edge research about the wonderful healing properties of niacin! Vitamin B3—or niacin—is a small molecule made of only fourteen atoms, smaller even than the simplest sugar. But this one molecule has profound effects on health: it plays a role in more than five hundred reactions in the body. Many illnesses are caused by too little niacin, and many illnesses can be cured with high doses of niacin. The updated and expanded second edition features: Detailed recommendations on the forms and therapeutic doses of niacin Updated information on niacin side effects and safety The most effective ways to use niacin for arthritis, learning and behavioral disorders, mental illness, cardiovascular disease, and other conditions Niacin: The Real Story takes an orthomolecular (nutrition-based) approach to medicine, supporting wellness with substances that naturally occur in the human body. In this groundbreaking second edition, the most prominent minds in orthomolecular medicine return with an expanded discussion of the widespread use of niacin for the prevention and treatment of health problems.
Author: Dmitry I Gabrilovich
Publisher: World Scientific
ISBN: 1783260629
Category : Science
Languages : en
Pages : 378
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Book Description
This is a second edition of the book, which presents an overview of the most recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections and have been implicated in anti-tumor response. In addition, neutrophils represent a unique model for studying fundamental questions of cellular biochemistry and molecular biology. This book provides a detailed description of signal transduction, generation of reactive oxygen, and mechanisms of migration of these cells. It contains unique information on the neutrophil's role in viral infectious diseases and cancer. It also presents the recent advances in attempts to improve neutrophil function and use these cells in the treatment of diseases.
Author: Wendell A. Lim
Publisher: CRC Press
ISBN: 1040010830
Category : Science
Languages : en
Pages : 464
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Book Description
Cell Signaling provides undergraduate and graduate students with the conceptual tools needed to make sense of the dizzying array of pathways that cells use to detect, process, and respond to signals from the environment. By emphasizing the common design principles and molecular processes that underlie all signaling mechanisms, the book develops a broad conceptual framework through which students can understand diverse signaling pathways and networks. The book first examines the common currencies of cellular information processing and the core components of the signaling machinery. It then shows how these individual components link together into networks and pathways to perform more sophisticated tasks. Many specific examples are provided throughout to illustrate common principles, and to provide a comprehensive overview of major signaling pathways. Thoroughly revised, this second edition includes two new chapters and substantial updates to the text and figures throughout the book. Key features: The book provides a conceptual framework through which all signaling pathways can be understood without memorization of details It is extensively illustrated, including high-quality diagrams and schematics to elucidate important concepts and processes Each chapter concludes with a useful summary section that brings together the key concepts End-of-chapter review questions test the reader’s understanding of the material covered Two new chapters have been written especially for this edition: "Signaling and Disease" and "Diversity in Signaling across Phylogeny"
Author: Stephen Harrod Buhner
Publisher: Storey Publishing, LLC
ISBN: 1635864186
Category : Health & Fitness
Languages : en
Pages : 603
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Book Description
Viruses are smart, mutating, and becoming resistant to antiviral pharmaceuticals. Global crises such as COVID-19, SARS, and dengue feaver spread more quickly than we can develop medicines to fight them. Herbalist and best-selling author Stephen Harrod Buhner has studied the antiviral properties of plants for many years. In this comprehensive guide, he profiles the plants that have proven most effective in fighting viral infections and provides in-depth instructions for preparing and using formulations to address the most common infections and strengthen immunity, safely and naturally. The updated 2nd edition includes an expanded guide to COVID-19, including a review of the most up-to-date medical research and the plant medicines that have been found to be most potent in preventing infection, lessening the impact of the virus on the body, and addressing longer-term effects and co-infections. This publication conforms to the EPUB Accessibility specification at WCAG 2.0 Level AA.
Author: Mary Sheppard
Publisher: CRC Press
ISBN: 1444128671
Category : Medical
Languages : en
Pages : 345
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Book Description
The second edition of Practical Cardiovascular Pathology provides an essential text and colour atlas helping all general pathologists to identify a wide range of cardiovascular conditions rapidly and accurately in both their diagnostic and autopsy work.With many new conditions explained, and numerous new illustrations, the second edition of this hi
Author: Nathan D. Zasler, MD
Publisher: Demos Medical Publishing
ISBN: 1936287277
Category : Medical
Languages : en
Pages : 1549
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Book Description
This book is a clear and comprehensive guide to all aspects of the management of traumatic brain injury-from early diagnosis and evaluation through the post-acute period and rehabilitation. An essential reference for physicians and other health care professionals who work with brain injured patients, the book focuses on assessment and treatment of the wider variety of clinical problems these patients face and addresses many associated concerns such as epidemiology, ethical issues, legal issues, and life-care planning. Written by over 190 acknowledged leaders, the text covers the full spectrum of the practice of brain injury medicine including principles of neural recovery, neuroimaging and neurodiagnostic testing, prognosis and outcome, acute care, rehabilitation, treatment of specific populations, neurologic and other medical problems following injury, cognitive and behavioral problems, post-traumatic pain disorders, pharmacologic and alternative treatments, and community reentry and productivity.
Author: Tommaso Pizzorusso
Publisher: Frontiers Media SA
ISBN: 2889456579
Category : Neurosciences. Biological psychiatry. Neuropsychiatry
Languages : en
Pages : 346
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Book Description
Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory role of nc-RNAs exert in many biological processes. Overall, these studies are making increasingly clear that, both in model organisms and in humans, complexity is not a function of the number of protein-coding genes, but results from the possibility of using combinations of genetic programs and controlling their spatial and temporal regulation during development, senescence and in disease by regulatory RNAs. This has generated a novel picture of gene regulatory networks where regulatory nc-RNAs represent novel layers of regulation. Particularly well-characterized is the role of microRNAs (miRNAs), small nc-RNAs, that bind to mRNAs and regulate gene expression after transcritpion. This message is particularly clear in the nervous system, where miRNAs have been involved in regulating cellular pathways controlling fundamental functions during development, synaptic plasticity and in neurodegenerative disease. It has also been shown that neuronal miRNAs are tightly regulated by electrical activity at the level of transcription, biogenesis, stability and specifically targeted to dendrites and synapses. Deregulation of expression of miRNAs is proposed not only as potential disease biomarker, but it has been implicated directly in the pathogenesis of complex neurodegenerative disease. This so-called RNA revolution also lead to the exploitation of RNA interference and the development of related tools as potential treatment of a vast array of CNS disease that could benefit from regulation of disease-associated genes. In spite of these advancements, the relatively young age of this field together with the inherent high molecular complexity of RNA regulation of biological processes have somewhat hindered its communication to the whole of the neuroscience community. This Research Topic aims at improving this aspect by putting around the same virtual table scientists covering aspects ranging from basic molecular mechanisms of regulatory RNAs in the nervous system to the analysis of the role of specific regulatory RNAs in neurobiological processes of development, plasticity and aging. Furthermore, we included papers analyzing the role of regulatory RNAs in disease models from neuromuscular to higher cognitive functions, and more technically oriented papers dealing with new methodologies to study regulatory RNA biology and its translational potential.
