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Author: Yoshimasa Kyōgoku
Publisher:
ISBN:
Category : DNA-protein interactions
Languages : en
Pages : 0
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Book Description
Author: Yoshimasa Kyōgoku
Publisher:
ISBN:
Category : DNA-protein interactions
Languages : en
Pages : 0
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Book Description
Author: Davies
Publisher: CRC-Press
ISBN: 9780849377686
Category : Science
Languages : en
Pages :
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Book Description
Author: Davies
Publisher: CRC-Press
ISBN: 9780849377686
Category : Science
Languages : en
Pages : 0
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Book Description
Focuses on the role of structural variations of DNA and proteins in gene regulation. Transcription factors, newly-proposed structural motifs and interactions between DNA and DNA-binding domains are discussed.
Author: JASON A. MCEVOY
Publisher: Lulu.com
ISBN: 0359602312
Category : Chemistry
Languages : en
Pages : 322
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Book Description
Author: Organizing Committee, Yokohama Forum for the 21st Century
Publisher:
ISBN:
Category :
Languages : en
Pages : 111
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Book Description
Author:
Publisher: Ardent Media
ISBN:
Category : DNA.
Languages : en
Pages : 8
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Book Description
Author: Stephen Neidle
Publisher: Oxford University Press, USA
ISBN: 9780198506355
Category : Medical
Languages : en
Pages : 212
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Book Description
This book provides a detailed view of the molecular structures of DNA and RNA and how they are recognised by small molecules and proteins. Extensive source material is provided, including information on relevant web sites and computer programmes. The major methods of structural investigation for nucleic acids: X-ray crystallography, NMR, and molecular modelling are reviewed and their scope and limitations (in the context of nucleic acids) discussed. Also covered are the conformational features of nucleic acid building blocks, including a description of how base-pair morphologies are analysed; the structures of DNA double helices and helical oligonucleotides, emphasising current ideas on sequence-dependent structure; and DNA-DNA interactions, including triplexes and quadruplexes. The principles of RNA folding, ribosome, and ribozyme structure are also surveyed. Both covalent and non-covalent nucleic acid interactions with small molecules are described, with the emphasis on recognition principles and sequence specific gene recognition. The principles of protein - nucleic acid are covered, focussing on regulatory proteins. Nucleic Acid Structure and Recognition will therefore equip readers with a good understanding of all the important aspects of this major field. The Nucleic Acid Database (NDB) crystallographic and NMR structures for the nucleic acid structures described in the book are freely available through the Nucleic Acid Structure and Recognition website.
Author: Paul Archer Thiessen
Publisher:
ISBN:
Category :
Languages : en
Pages : 304
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Book Description
Author: F. Diederich
Publisher: Springer Science & Business Media
ISBN: 366203574X
Category : Science
Languages : en
Pages : 274
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Book Description
Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, it is clearly recognized that molecular recognition impacts and determines all life processes. It has become a key research field in both chemistry and biology and the emerging interface of what now is being called "chemical biology". The technological advances derived from this knowledge are particularly important, diverse, and directly evident in the pharmaceutical industry. Under the auspices of the Ernst Schering Research Foundation, a workshop held in Berlin in February 1998 addressed novel basic developments of potential relevance to drug research efforts. A balance of timely research topics in molecular recognition is presented in the lectures delivered by a multidisciplinary international panel of renowned scholars and documented in this volume.
Author: A.D. Buckingham
Publisher: Springer Science & Business Media
ISBN: 9780751401257
Category : Science
Languages : en
Pages : 232
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Book Description
The importance of molecular recognition in chemistry and biology is reflected in a recent upsurge in relevant research, promoted in particular by high-profile initiatives in this area in Europe, the USA and Japan. Although molecular recognition is necessarily microscopic in origin, its consequences are de facto macroscopic. Accordingly, a text that starts with intermolecular interactions between simple molecules and builds to a discussion of molecular recognition involving larger scale systems is timely. This book was planned with such a development in mind. The book begins with an elementary but rigorous account of the various types of forces between molecules. Chapter 2 is concerned with the hydrogen bond between pairs of simple molecules in the gas phase, with particular reference to the preferred relative orientation of the pair and the ease with which this can be distorted. This microscopic view continues in chapter 3 wherein the nature of interactions between solute molecules and solvents or between two or more solutes is examined from the experimental standpoint, with various types of spectroscopy providing the probe of the nature of the interactions. Molecular recognition is central to the catalysis of chemical reactions, especially when bonds are to be broken and formed under the severe con straint that a specific configuration is to result, as in the production of enan tiotopically pure compounds. This important topic is considered in chapter 4.
