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Author: Devendra K. Chaturvedi
Publisher: CRC Press
ISBN: 143980673X
Category : Computers
Languages : en
Pages : 734
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Book Description
Not only do modeling and simulation help provide a better understanding of how real-world systems function, they also enable us to predict system behavior before a system is actually built and analyze systems accurately under varying operating conditions. Modeling and Simulation of Systems Using MATLAB® and Simulink® provides comprehensive, state-of-the-art coverage of all the important aspects of modeling and simulating both physical and conceptual systems. Various real-life examples show how simulation plays a key role in understanding real-world systems. The author also explains how to effectively use MATLAB and Simulink software to successfully apply the modeling and simulation techniques presented. After introducing the underlying philosophy of systems, the book offers step-by-step procedures for modeling different types of systems using modeling techniques, such as the graph-theoretic approach, interpretive structural modeling, and system dynamics modeling. It then explores how simulation evolved from pre-computer days into the current science of today. The text also presents modern soft computing techniques, including artificial neural networks, fuzzy systems, and genetic algorithms, for modeling and simulating complex and nonlinear systems. The final chapter addresses discrete systems modeling. Preparing both undergraduate and graduate students for advanced modeling and simulation courses, this text helps them carry out effective simulation studies. In addition, graduate students should be able to comprehend and conduct simulation research after completing this book.
Author: Devendra K. Chaturvedi
Publisher: CRC Press
ISBN: 143980673X
Category : Computers
Languages : en
Pages : 734
Get Book Here
Book Description
Not only do modeling and simulation help provide a better understanding of how real-world systems function, they also enable us to predict system behavior before a system is actually built and analyze systems accurately under varying operating conditions. Modeling and Simulation of Systems Using MATLAB® and Simulink® provides comprehensive, state-of-the-art coverage of all the important aspects of modeling and simulating both physical and conceptual systems. Various real-life examples show how simulation plays a key role in understanding real-world systems. The author also explains how to effectively use MATLAB and Simulink software to successfully apply the modeling and simulation techniques presented. After introducing the underlying philosophy of systems, the book offers step-by-step procedures for modeling different types of systems using modeling techniques, such as the graph-theoretic approach, interpretive structural modeling, and system dynamics modeling. It then explores how simulation evolved from pre-computer days into the current science of today. The text also presents modern soft computing techniques, including artificial neural networks, fuzzy systems, and genetic algorithms, for modeling and simulating complex and nonlinear systems. The final chapter addresses discrete systems modeling. Preparing both undergraduate and graduate students for advanced modeling and simulation courses, this text helps them carry out effective simulation studies. In addition, graduate students should be able to comprehend and conduct simulation research after completing this book.
Author: Weijiu Liu
Publisher: Springer Science & Business Media
ISBN: 8847024900
Category : Mathematics
Languages : en
Pages : 275
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Book Description
This textbook contains the essential knowledge in modeling, simulation, analysis, and applications in dealing with biological cellular control systems. In particular, the book shows how to use the law of mass balance and the law of mass action to derive an enzyme kinetic model - the Michaelis-Menten function or the Hill function, how to use a current-voltage relation, Nernst potential equilibrium equation, and Hodgkin and Huxley's models to model an ionic channel or pump, and how to use the law of mass balance to integrate these enzyme or channel models into a complete feedback control system. The book also illustrates how to use data to estimate parameters in a model, how to use MATLAB to solve a model numerically, how to do computer simulations, and how to provide model predictions. Furthermore, the book demonstrates how to conduct a stability and sensitivity analysis on a model.
Author: Brian P. Ingalls
Publisher: MIT Press
ISBN: 0262545829
Category : Science
Languages : en
Pages : 423
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Book Description
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Author: Andres Kriete
Publisher: Academic Press
ISBN: 0124059384
Category : Science
Languages : en
Pages : 549
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Book Description
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Author: Pavel Kraikivski
Publisher: Springer Nature
ISBN: 3030677427
Category : Science
Languages : en
Pages : 310
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Book Description
This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relevant details with regard to cell physiology and molecular mechanisms? How are the details put together into a mathematical model? How is the model analyzed and simulated? What are the results of the model? How do they compare to the known facts of the cell physiology? Does the model make predictions? What can be done to extend the model? The book presents a summary of results and references to more relevant sources. The volume contains the classic collection of topics and studies that are well established yet novel in the systems biology field.
Author: Kenneth R. Dixon
Publisher: CRC Press
ISBN: 1439855188
Category : Mathematics
Languages : en
Pages : 258
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Book Description
Exploring roles critical to environmental toxicology, Modeling and Simulation in Ecotoxicology with Applications in MATLAB and Simulink covers the steps in modeling and simulation from problem conception to validation and simulation analysis. Using the MATLAB and Simulink programming languages, the book presents examples of mathematical functions a
Author: Sergey N. Makarov
Publisher: John Wiley & Sons
ISBN: 1119052467
Category : Science
Languages : en
Pages : 616
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Book Description
Provides a detailed and systematic description of the Method of Moments (Boundary Element Method) for electromagnetic modeling at low frequencies and includes hands-on, application-based MATLAB® modules with user-friendly and intuitive GUI and a highly visualized interactive output. Includes a full-body computational human phantom with over 120 triangular surface meshes extracted from the Visible Human Project® Female dataset of the National library of Medicine and fully compatible with MATLAB® and major commercial FEM/BEM electromagnetic software simulators. This book covers the basic concepts of computational low-frequency electromagnetics in an application-based format and hones the knowledge of these concepts with hands-on MATLAB® modules. The book is divided into five parts. Part 1 discusses low-frequency electromagnetics, basic theory of triangular surface mesh generation, and computational human phantoms. Part 2 covers electrostatics of conductors and dielectrics, and direct current flow. Linear magnetostatics is analyzed in Part 3. Part 4 examines theory and applications of eddy currents. Finally, Part 5 evaluates nonlinear electrostatics. Application examples included in this book cover all major subjects of low-frequency electromagnetic theory. In addition, this book includes complete or summarized analytical solutions to a large number of quasi-static electromagnetic problems. Each Chapter concludes with a summary of the corresponding MATLAB® modules. Combines fundamental electromagnetic theory and application-oriented computation algorithms in the form of stand alone MATLAB® modules Makes use of the three-dimensional Method of Moments (MoM) for static and quasistatic electromagnetic problems Contains a detailed full-body computational human phantom from the Visible Human Project® Female, embedded implant models, and a collection of homogeneous human shells Low-Frequency Electromagnetic Modeling for Electrical and Biological Systems Using MATLAB® is a resource for electrical and biomedical engineering students and practicing researchers, engineers, and medical doctors working on low-frequency modeling and bioelectromagnetic applications.
Author: Huimin Zhao
Publisher: Springer
ISBN: 3319553186
Category : Technology & Engineering
Languages : en
Pages : 326
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Book Description
This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Author: Michael Small
Publisher: CRC Press
ISBN: 1439853363
Category : Mathematics
Languages : en
Pages : 286
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Book Description
From the spontaneous rapid firing of cortical neurons to the spatial diffusion of disease epidemics, biological systems exhibit rich dynamic behaviour over a vast range of time and space scales. Unifying many of these diverse phenomena, Dynamics of Biological Systems provides the computational and mathematical platform from which to understand the underlying processes of the phenomena. Through an extensive tour of various biological systems, the text introduces computational methods for simulating spatial diffusion processes in excitable media, such as the human heart, as well as mathematical tools for dealing with systems of nonlinear ordinary and partial differential equations, such as neuronal activation and disease diffusion. The mathematical models and computer simulations offer insight into the dynamics of temporal and spatial biological systems, including cardiac pacemakers, artificial electrical defibrillation, pandemics, pattern formation, flocking behaviour, the interaction of autonomous agents, and hierarchical and structured network topologies. Tools from complex systems and complex networks are also presented for dealing with real phenomenological systems. With exercises and projects in each chapter, this classroom-tested text shows students how to apply a variety of mathematical and computational techniques to model and analyze the temporal and spatial phenomena of biological systems. MATLAB® implementations of algorithms and case studies are available on the author’s website.
Author: Pierpaolo Degano
Publisher: Springer
ISBN: 364203845X
Category : Science
Languages : en
Pages : 337
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Book Description
This volume contains the proceedings of the 7th Conference on Computational Methods in Systems Biology (CMSB 2009), held in Bologna, from August 31 to September 1, 2009. The ?rst CMSB was held in Trento in 2003, bringing together life scientists, computer scientists, engineers and physicists. The goal was to promote the c- vergence of di?erent disciplines aiming at a new understanding and description of biological systems, ?rmly ground in formal models, supported by compu- tionallanguagesandtools,ando?eringnew methodsofanalysis.The conference then moved to Paris in 2004, Edinburgh in 2005, Trento in 2006, Edinburgh in 2007 and Rostock/Warnemunde ̈ in 2008. This year the conference attracted about 45 submissions form 18 countries, mainly from Europe and North America, but also from Asia and Australia. We wish to thank all authors for their interest in CMSB 2009. After careful disc- sions, the Programme Committee eventually selected 18 papers for presentation at the conference. Each of them was accurately refereed by at least three - viewers, who delivered detailed and insightful comments and suggestions. The Conference Chairmen warmly thank all the members of the Programme C- mittee and all their sub-referees for the excellent support they gave, as well as for the friendly and constructive discussions. We also would like to thank the authorsfor havingrevisedtheir papers to addressthe comments andsuggestions by the referees.
