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Author: Chih-Wei Yang
Publisher: S. Karger AG (Switzerland)
ISBN: 9783318065398
Category : Kidneys
Languages : en
Pages : 0
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Book Description
Leptospirosis is the most common zoonotic disease worldwide, involving at least 1 million patients annually. Kidney is the preferential colonization site where Leptospira accumulates during systemic infection, primarily in the interstitium and in renal tubule epithelial cells. In acute kidney injury (AKI), the main histological findings are acute tubulo-interstitial nephritis and acute tubular necrosis, characterized by hypokalemia and non-oliguria. The injury caused by leptospira outer membrane protein components involves innate immunity Toll-like receptor pathways and activation of complement and immune cascades in the kidney, together with extracellular matrix accumulation when the kidney infection progress to chronic kidney disease (CKD). Significantly, recent studies indicate that leptospira may induce CKD in humans either with AKI-CKD continuum or subclinical leptospira infection leading to CKD. Leptospirosis kidney disease thus represents a newly discovered and previously overlooked area requiring intensive medical and public health attention and investigation. In this book, leading experts in the field contribute their cutting-edge clinical and research experiences for the understanding of leptospirosis kidney disease. The outstanding feature of this publication is emphasizing kidney injury and disease induced by leptospirosis, an underestimated infection involving multiple organs. The book contributes information on current knowledge of leptospirosis kidney disease and a new perspective for future research.
Author: Chih-Wei Yang
Publisher: S. Karger AG (Switzerland)
ISBN: 9783318065398
Category : Kidneys
Languages : en
Pages : 0
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Book Description
Leptospirosis is the most common zoonotic disease worldwide, involving at least 1 million patients annually. Kidney is the preferential colonization site where Leptospira accumulates during systemic infection, primarily in the interstitium and in renal tubule epithelial cells. In acute kidney injury (AKI), the main histological findings are acute tubulo-interstitial nephritis and acute tubular necrosis, characterized by hypokalemia and non-oliguria. The injury caused by leptospira outer membrane protein components involves innate immunity Toll-like receptor pathways and activation of complement and immune cascades in the kidney, together with extracellular matrix accumulation when the kidney infection progress to chronic kidney disease (CKD). Significantly, recent studies indicate that leptospira may induce CKD in humans either with AKI-CKD continuum or subclinical leptospira infection leading to CKD. Leptospirosis kidney disease thus represents a newly discovered and previously overlooked area requiring intensive medical and public health attention and investigation. In this book, leading experts in the field contribute their cutting-edge clinical and research experiences for the understanding of leptospirosis kidney disease. The outstanding feature of this publication is emphasizing kidney injury and disease induced by leptospirosis, an underestimated infection involving multiple organs. The book contributes information on current knowledge of leptospirosis kidney disease and a new perspective for future research.
Author: Ben Adler
Publisher: Springer
ISBN: 3662450593
Category : Medical
Languages : en
Pages : 295
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Book Description
This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis.
Author: Paola S. Timiras
Publisher: CRC Press
ISBN: 1420007092
Category : Medical
Languages : en
Pages : 426
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Book Description
Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields.
Author: Neil N. Turner
Publisher: Oxford University Press
ISBN: 0191017655
Category : Medical
Languages : en
Pages : 3045
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Book Description
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.
Author: W. J. Terpstra
Publisher: World Health Organization
ISBN: 9241545895
Category : Medical
Languages : en
Pages : 121
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Book Description
Leptospirosis is a potentially serious but treatable zoonotic disease representing a worldwide public health hazard. Its symptoms may mimic those of a number of other unrelated infections such as influenza meningitis hepatitis dengue or viral haemorrhagic fevers. It is important to distinguish leptospirosis from these diseases. For this reason new diagnostic methods have been developed in recent years. In humid tropical and subtropical areas where most developing countries are located leptospirosis poses a greater health problem than in areas with a temperate climate. Because leptospirosis is easily overlooked and consequently underreported in many parts of the world it is necessary to increase awareness and knowledge of the disease as a public health threat. The aim of these guidelines is to assist in this process. The target groups to which these guidelines are directed consist of health workers clinicians laboratory technicians microbiologists public health workers veterinarians and biologists with an interest in zoonoses having no specialized knowledge of leptospirosis but who wish to be generally informed about the microorganism concerned and the disease that it may cause. This is not a handbook and avoids technical details but the interested reader can find further information in the annexes and the general bibliography. These guidelines are concerned essentially with human leptospirosis.
Author: Nicola Pusterla
Publisher: John Wiley & Sons
ISBN: 1118739795
Category : Medical
Languages : en
Pages : 444
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Book Description
Interpretation of Equine Laboratory Diagnostics offers a comprehensive approach to equine laboratory diagnostics, including hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics. Offers a practical resource for the accurate interpretation of laboratory results, with examples showing real-world applications Covers hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics Introduces the underlying principles of laboratory diagnostics Provides clinically oriented guidance on performing and interpreting laboratory tests Presents a complete reference to establish and new diagnostic procedures Offers a practical resource for the accurate interpretation of laboratory results, with examples showing real-world applications Covers hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics Introduces the underlying principles of laboratory diagnostics Provides clinically oriented guidance on performing and interpreting laboratory tests Presents a complete reference to established and new diagnostic procedures
Author: Centers for Disease Control and Prevention CDC
Publisher: Oxford University Press
ISBN: 0190628634
Category : Medical
Languages : en
Pages : 705
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Book Description
THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
ISBN: 1464805202
Category : Medical
Languages : en
Pages : 948
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Book Description
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantialburden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significanteconomic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at theclinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
Author: Jane E. Sykes
Publisher: Elsevier Health Sciences
ISBN: 0323241948
Category : Medical
Languages : en
Pages : 933
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Book Description
Canine and Feline Infectious Diseases is a practical, up-to-date resource covering the most important and cutting-edge advances in the field. Presented by a seasoned educator in a concise, highly visual format, this innovative guide keeps you current with the latest advances in this ever-changing field. 80 case studies illustrate the clinical relevance of the major infectious disease chapters. - Well-organized Major Infectious Diseases chapters break down content by etiologic agent and epidemiology, clinical signs and their pathophysiology, physical examination findings, diagnosis, treatment and prognosis, immunity, prevention, and public health implications. - Over 80 case studies illustrate how the information provided can be applied in everyday practice. - Logical approach to laboratory diagnosis guides you through all the steps needed to accurately diagnose and treat viral, bacterial, fungal, protozoal, and algal diseases. - Practical protocols provided by expert clinicians guide you in the management of canine and feline patients suspected to have infectious diseases, including handling, disinfection, isolation, and vaccination protocols. - Over 500 full color images – geographic distribution maps, life cycle drawings, and hundreds of color photographs – visually illustrate and clarify complex issues. - Easy-to-understand tables and boxes make content quickly accessible, eliminating the need to sort through dense text for critical information in the clinical setting.
Author: Ryane E. Englar
Publisher: John Wiley & Sons
ISBN: 1119414601
Category : Medical
Languages : de
Pages : 2349
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Book Description
Common Clinical Presentations in Dogs and Cats ist ein verlässliches Referenzwerk zum schnellen Nachschlagen der wichtigsten Informationen, um Erkrankungen bei Hunden und Katzen zu diagnostizieren. Häufige klinische Zustände lassen sich anhand des problemorientierten Ansatzes erkennen. Diagnose und Behandlungspläne werden eingeführt. Das Buch ist sowohl für Studenten der Veterinärmedizin als auch Kliniker ein nützliches Nachschlagewerk mit 78 Kapiteln, die die verschiedenen Körpersysteme beschreiben. Jedes Kapitel konzentriert sich auf die Hauptbeschwerden, erläutert mögliche Diagnosen und bestimmt den klinischen Pflegeansatz. Eine Fülle von Illustrationen, klinischen Fotos und Zeichnungen veranschaulichen die präsentierten Konzepte. Common Clinical Presentations in Dogs and Cats ist ein wichtiges Referenzwerk mit den folgenden Merkmalen: - Kliniker erhalten schnellen Zugriff auf Detailinformatione, um gängige Erkrankungen bei Hunden und Katzen zu erkennen und korrekt zu diagnostizieren. - Präsentiert die Informationen nach den jeweiligen klinischen Anzeichen und zu dem entsprechenden Körpersystem. - Alle Kapitel sind einheitlich aufgebaut und ermöglichen so das schnelle Nachschlagen. - Beinhaltet Farbfotos und Zeichnungen zur Veranschaulichung der Symptome. Common Clinical Presentations in Dogs and Cats richtet sich an Veterinärmediziner für Kleintiere und Studenten der Veterinärmedizin, ist als Referenzwerk für die Praxis konzipiert und vermittelt das notwendige Fachwissen, um eine Vielzahl von Erkrankungen verlässlich zu diagnostizieren.
