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Author: L. Diane Mull
Publisher:
ISBN:
Category : AIDS (Disease)
Languages : en
Pages : 103
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Book Description
Author: L. Diane Mull
Publisher:
ISBN:
Category : AIDS (Disease)
Languages : en
Pages : 103
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Book Description
Author:
Publisher:
ISBN:
Category : Child labor
Languages : en
Pages : 446
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Book Description
Author: International Labour Office
Publisher: International Labor Office
ISBN:
Category : Age and employment
Languages : en
Pages : 108
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Book Description
How can we reduce child labor in the unfavorable circumstances of a global economic slowdown? This new flagship report, the first in a series to be published annually by the ILO's International Program on the Elimination of Child Labor, brings together research on child labor and social protection, identifying policies that are designed to achieve multiple social goals. This report includes analyses of national child labor trends based on the latest survey data, discussions of the role of poverty and economic shocks in rendering households vulnerable to child labor, and detailed consideration of income transfers, public employment programs, social insurance, and microcredit initiatives as they have been implemented around the world. The report distills a broad range of research in economic and social policy and should be of interest to those looking for ways to combat poverty in the present and reduce its burden on the next generation.
Author: Arvil V. Adams
Publisher: World Bank Publications
ISBN: 0821399691
Category : Education
Languages : en
Pages : 295
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Book Description
This book uses household surveys in five countries of Sub-Saharan Africa to describe employment off the farm in the region s growing informal sector and assesses how different forms of education and training, including apprenticeships, influence choices in employment and earnings.
Author: Mohammadreza Shalbafan
Publisher: Frontiers Media SA
ISBN: 2832530982
Category : Medical
Languages : en
Pages : 99
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Book Description
Author: Michael J. McPhaden
Publisher: John Wiley & Sons
ISBN: 1119548128
Category : Science
Languages : en
Pages : 528
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Book Description
Comprehensive and up-to-date information on Earth’s most dominant year-to-year climate variation The El Niño Southern Oscillation (ENSO) in the Pacific Ocean has major worldwide social and economic consequences through its global scale effects on atmospheric and oceanic circulation, marine and terrestrial ecosystems, and other natural systems. Ongoing climate change is projected to significantly alter ENSO's dynamics and impacts. El Niño Southern Oscillation in a Changing Climate presents the latest theories, models, and observations, and explores the challenges of forecasting ENSO as the climate continues to change. Volume highlights include: Historical background on ENSO and its societal consequences Review of key El Niño (ENSO warm phase) and La Niña (ENSO cold phase) characteristics Mathematical description of the underlying physical processes that generate ENSO variations Conceptual framework for understanding ENSO changes on decadal and longer time scales, including the response to greenhouse gas forcing ENSO impacts on extreme ocean, weather, and climate events, including tropical cyclones, and how ENSO affects fisheries and the global carbon cycle Advances in modeling, paleo-reconstructions, and operational climate forecasting Future projections of ENSO and its impacts Factors influencing ENSO events, such as inter-basin climate interactions and volcanic eruptions The American Geophysical Union promotes discovery in Earth and space science for the benefit of humanity. Its publications disseminate scientific knowledge and provide resources for researchers, students, and professionals. Find out more about this book from this Q&A with the editors.
Author: Albin Debevec
Publisher:
ISBN: 9789612381288
Category :
Languages : sl
Pages : 101
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Book Description
Author: Jesus Avila
Publisher: Frontiers E-books
ISBN: 288919261X
Category : Medicine (General)
Languages : en
Pages : 114
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Book Description
Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.
Author: Madeleine J. H. van Oppen
Publisher: Springer
ISBN: 3319753932
Category : Science
Languages : en
Pages : 357
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Book Description
One of the most serious consequences of global climate change for coral reefs is the increased frequency and severity of mass coral bleaching events and, since the first edition of this volume was published in 2009, there have been additional mass coral bleaching events. This book provides comprehensive information on the causes and consequences of coral bleaching for coral reef ecosystems, from the genes and microbes involved in the bleaching response, to individual coral colonies and whole reef systems. It presents detailed analyses of how coral bleaching can be detected and quantified and reviews future scenarios based on modeling efforts and the potential mechanisms of acclimatisation and adaptation. It also briefly discusses emerging research areas that focus on the development of innovative interventions aiming to increase coral climate resilience and restore reefs.
Author: Margaret M. Esiri
Publisher: Cambridge University Press
ISBN: 9780521819152
Category : Medical
Languages : en
Pages : 600
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Book Description
Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
