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Author: Katharina Schmidt-Bleek
Publisher: Frontiers Media SA
ISBN: 2832546358
Category : Medical
Languages : en
Pages : 123
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Book Description
Author: Katharina Schmidt-Bleek
Publisher: Frontiers Media SA
ISBN: 2832546358
Category : Medical
Languages : en
Pages : 123
Get Book Here
Book Description
Author: Stephen F. Badylak
Publisher: Woodhead Publishing
ISBN: 0128214562
Category : Technology & Engineering
Languages : en
Pages : 296
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Book Description
Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. - Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response - Provides a single reference for understanding and utilizing the host response in biomaterials design - An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Author: Laurence J. Kirmayer
Publisher: Cambridge University Press
ISBN: 1108580572
Category : Psychology
Languages : en
Pages : 694
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Book Description
Recent neuroscience research makes it clear that human biology is cultural biology - we develop and live our lives in socially constructed worlds that vary widely in their structure values, and institutions. This integrative volume brings together interdisciplinary perspectives from the human, social, and biological sciences to explore culture, mind, and brain interactions and their impact on personal and societal issues. Contributors provide a fresh look at emerging concepts, models, and applications of the co-constitution of culture, mind, and brain. Chapters survey the latest theoretical and methodological insights alongside the challenges in this area, and describe how these new ideas are being applied in the sciences, humanities, arts, mental health, and everyday life. Readers will gain new appreciation of the ways in which our unique biology and cultural diversity shape behavior and experience, and our ongoing adaptation to a constantly changing world.
Author: Thomas Pradeu
Publisher: Cambridge University Press
ISBN: 1108575021
Category : Science
Languages : en
Pages :
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Book Description
Immunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what makes it unique, how its boundaries are established and what ensures its identity through time. Immunology also offers answers to some of the most interesting philosophical questions. What is the definition of life? How are bodily systems delineated? How do the mind and the body interact? In this Element, Thomas Pradeu considers the ways in which immunology can shed light on these and other important philosophical issues. This title is also available as Open Access on Cambridge Core.
Author: L Hench
Publisher: Elsevier
ISBN: 1845690869
Category : Science
Languages : en
Pages : 298
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Book Description
Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. - Comprehensive introduction to living and man-made materials - Looks at clinical applications of various biomaterials and devices - Bioengineering principles, materials and designs used in artificial organs are summarised
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309132967
Category : Medical
Languages : en
Pages : 359
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Book Description
Second in a series of publications from the Institute of Medicine's Quality of Health Care in America project Today's health care providers have more research findings and more technology available to them than ever before. Yet recent reports have raised serious doubts about the quality of health care in America. Crossing the Quality Chasm makes an urgent call for fundamental change to close the quality gap. This book recommends a sweeping redesign of the American health care system and provides overarching principles for specific direction for policymakers, health care leaders, clinicians, regulators, purchasers, and others. In this comprehensive volume the committee offers: A set of performance expectations for the 21st century health care system. A set of 10 new rules to guide patient-clinician relationships. A suggested organizing framework to better align the incentives inherent in payment and accountability with improvements in quality. Key steps to promote evidence-based practice and strengthen clinical information systems. Analyzing health care organizations as complex systems, Crossing the Quality Chasm also documents the causes of the quality gap, identifies current practices that impede quality care, and explores how systems approaches can be used to implement change.
Author: Wolfram Höland
Publisher: Frontiers Media SA
ISBN: 2889198014
Category : Bioactive glasses
Languages : en
Pages : 119
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Book Description
Inorganic biomaterials include materials for e.g. dental restorations, biocompatible materials for orthopedic appliances and bioactive materials. However, inorganic biomaterials are also developed for use in tissue regeneration, e.g. wound healing. These products either consist of crystalline phases, such as Al2O3 or ZrO2, which makes them suitable for use in hip bone replacement or they are composed of tricalcium phosphate and used as resorbable biomaterials. Or, they contain glassy phases, such as BIOGLASS®, and are employed as bioactive biomaterials to bond to living bone. Inorganic biomaterials are also used to develop inorganic – organic composites which are suitable for use as bioactive products or to produce dental filling materials. In general, the development of composites is state of the art. However, it is also a future technology. Biomaterials for dental restorations consist of glassy or crystalline phases. Glass-ceramics represent a special group of inorganic biomaterials for dental restorations. Glass-ceramics are composed of at least one inorganic glassy phase and at least one crystalline phase. These products demonstrate a combination of properties, which include excellent aesthetics and the ability to mimic the optical properties of natural teeth, as well as high strength and toughness. They can be processed using special processing procedures, e.g. machining, moulding and sintering, to fabricate high quality products. Sintered oxide ceramics, such as Al2O3 or ZrO2, are also used for the fabrication of dental restorations. These products can be veneered with other biomaterials, or they can be polished to achieve the best possible surface quality. The manuscripts dealing with inorganic biomaterials should focus on the development of the products, especially on their chemical nature, the phase formation processes and all the details related to their processing. Very important are the mechanisms of phase formation. The reader of the manuscript should understand all of these reactions in detail. As far as application is concerned, it is important to describe the main properties of the developed products based on the valid standards, e.g. the ISO standards. The papers published should show that the products comply with these standards. It is very important to understand the relationship between biomass and biomaterials. This will help young scientists to follow the development of biomaterials with new, unexpected properties. He manuscripts published in "Frontiers" should also focus on the application of the biomaterials. Every manuscript should show the most important application of the material presented. There are different journals that deal with specific product categories, eg "Dental Materials". However, "Frontiers" should allow young scientists to publish their research results using all kinds of inorganic biomaterials. On the other hand, fundamental discussion and analysis of the findings should be encouraged and conclusions about possible applications in the field of medicine and dentistry should be drawn.
Author: John A. Eddy
Publisher: Government Printing Office
ISBN: 9780160838088
Category : Business & Economics
Languages : en
Pages : 316
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Book Description
" ... Concise explanations and descriptions - easily read and readily understood - of what we know of the chain of events and processes that connect the Sun to the Earth, with special emphasis on space weather and Sun-Climate."--Dear Reader.
Author: Yuehuei H. An
Publisher: CRC Press
ISBN: 1420073567
Category : Medical
Languages : en
Pages : 650
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Book Description
The mechanical properties of whole bones, bone tissue, and the bone-implant interfaces are as important as their morphological and structural aspects. Mechanical Testing of Bone and the Bone-Implant Interface helps you assess these properties by explaining how to do mechanical testing of bone and the bone-implant interface for bone-related research
Author: Mihail C. Roco
Publisher: Springer Science & Business Media
ISBN: 9401703590
Category : Technology & Engineering
Languages : en
Pages : 477
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Book Description
M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.
