Insulin & Related Proteins — Structure to Function and Pharmacology PDF Download
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Author: Markus Leyck Dieken
Publisher: Springer Science & Business Media
ISBN: 1402006551
Category : Medical
Languages : en
Pages : 255
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Book Description
This book comprises an overview of insulin and other peptides in the context of structure, receptor interaction and pharmacological function, presented at the last Alcuin Symposium in Aachen, Germany, held in honor of the lifetime achievements of Prof. Axel Wollmer in the structural analysis of insulin. The major achievements in structural analysis of insulin, insulin analogues, receptor interaction and signal pathways are described by outstanding scientists in this field.
Author: Markus Leyck Dieken
Publisher: Springer Science & Business Media
ISBN: 1402006551
Category : Medical
Languages : en
Pages : 255
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Book Description
This book comprises an overview of insulin and other peptides in the context of structure, receptor interaction and pharmacological function, presented at the last Alcuin Symposium in Aachen, Germany, held in honor of the lifetime achievements of Prof. Axel Wollmer in the structural analysis of insulin. The major achievements in structural analysis of insulin, insulin analogues, receptor interaction and signal pathways are described by outstanding scientists in this field.
Author: Rodney Pearlman
Publisher: Springer Science & Business Media
ISBN: 1489912363
Category : Medical
Languages : en
Pages : 371
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Book Description
This is the first volume to make available specific case histories of therapeutic proteins and peptides that have been marketed or are currently under clinical testing. The editors have selected a wide range of molecules derived from monoclonal antibodies, recombinant DNA, and natural and chemical sources to provide formulation scientists with practical examples of the development of pharmaceutical products.
Author: Stefan Offermanns
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 1152
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Book Description
Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.
Author: R. A. DeFronzo
Publisher: John Wiley & Sons
ISBN: 1118387678
Category : Medical
Languages : en
Pages : 1200
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Book Description
The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting the substantial advances in the field. Whereas other diabetes textbooks are primarily clinical with less focus on the basic science behind diabetes, ITDM's primary philosophy has always been to comprehensively cover the basic science of metabolism, linking this closely to the pathophysiology and clinical aspects of the disease. Edited by four world-famous diabetes specialists, the book is divided into 13 sections, each section edited by a section editor of major international prominence. As well as covering all aspects of diabetes, from epidemiology and pathophysiology to the management of the condition and the complications that arise, this fourth edition also includes two new sections on NAFLD, NASH and non-traditional associations with diabetes, and clinical trial evidence in diabetes. This fourth edition of an internationally recognised textbook will once again provide all those involved in diabetes research and development, as well as diabetes specialists with the most comprehensive scientific reference book on diabetes available.
Author: Alan R. Saltiel
Publisher: Springer Science & Business Media
ISBN: 0387722041
Category : Medical
Languages : en
Pages : 223
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Book Description
More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems.
Author: Ashok K. Srivastava
Publisher: Springer Science & Business Media
ISBN: 1461556473
Category : Science
Languages : en
Pages : 189
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Book Description
In 1996 the 75th anniversary of the discovery of insulin was celebrated at the University of Toronto, the scene of that discovery in 1921. This volume was stimulated by the scientific program which was staged at that time and brought together much of the world's best talent to discuss and analyze the most recent developments in our understanding of pancreatic function, insulin secretion, the interaction of insulin with its target tissues, the mechanism of insulin action at the cellular level, and the defects which underlie both Type I (insulin-dependent diabetes mellitus, IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM) forms of the disease. We have chosen to focus the present volume on work related to insulin action.
Author: Michael Bliss
Publisher: University of Toronto Press
ISBN: 1487529139
Category : Diabetes
Languages : en
Pages : 351
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Book Description
This special centenary edition of The Discovery of Insulin celebrates a path-breaking medical discovery that has changed lives around the world.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Joseph Schlessinger
Publisher:
ISBN: 9781936113330
Category : Science
Languages : en
Pages : 0
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Book Description
Receptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epidermal growth factor, and nerve growth factor. They activate highly conserved intracellular signaling pathways that regulate cell proliferation, differentiation, and metabolism, playing essential roles in developing and adult animals. This book examines the nature of these receptors and their ligands, the molecular mechanisms that they regulate within cells, and the roles of the receptors in normal physiology and control of embryogenesis. It also discusses how dysfunction of these mechanisms can contribute to cancer and other diseases.
Author: Deric L. Wheeler
Publisher: Springer
ISBN: 3319118889
Category : Science
Languages : en
Pages : 888
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Book Description
This book devotes a chapter to each RTK family and the multiple receptors within each family, thoroughly covering all of the RTKs. The chapters all follow the same structure, presenting this essential information in an accessible and user-friendly format. Each chapter covers one specific family of receptors and begins with a general introduction to that family and a comprehensive discussion of that receptor’s family in development and human disease. Following are in-depth analyses of each family’s receptors with discussions on the gene, protein, ligands, activation, and signaling pathways along with discussion of receptor processing and signal attenuation. Further, cross talk with other receptors systems, post-translational modification and specific unique characteristics to each RTK are discussed. Because it isolates and explains each family, this book is an essential companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, by the same authors, which talks about RTKs more generally and without the family-by-family detail.
