IgE and Anti-IgE Therapy in Asthma and Allergic Disease PDF Download
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Author: Robert Fick
Publisher: CRC Press
ISBN: 0203909003
Category : Medical
Languages : en
Pages : 576
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Book Description
Exploring the role of Immunoglobulin-E (IgE) in human disease, this reference summarizes current research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic disease, inflammation, and asthma-discussing the structural composition of high- and low-affinity IgE receptors, the airway cells that express
Author: Robert Fick
Publisher: CRC Press
ISBN: 0203909003
Category : Medical
Languages : en
Pages : 576
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Book Description
Exploring the role of Immunoglobulin-E (IgE) in human disease, this reference summarizes current research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic disease, inflammation, and asthma-discussing the structural composition of high- and low-affinity IgE receptors, the airway cells that express
Author: S.H. Arshad
Publisher: CRC Press
ISBN: 9781841840901
Category : Medical
Languages : en
Pages : 64
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Book Description
Little new has been introduced into the armamentarium for asthma therapy in the last thirty years apart from improvements in b2-adrenoceptor agonists, corticosteroids and cysteinyl leukotriene antagonists. However, the introduction of a fully humanised monoclonal antibody to immunoglobulin E (IgE) (omalizumab), should provide a new way of treating allergic disorders, with effects that extend beyond a single affected organ and tissue. The precise role of this new agent in treatment guidelines will need to be carefully evaluated, but its clear efficacy and safety provide a strong statement about the importance of IgE across the full spectrum of allergic disease. This pocketbook provides an illustrative summary of the role of IgE in the pathogenesis of asthma and allied allergic disorders, as well as the effects of anti-IgE therapy in the management of these conditions.
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Michael Yeadon, PH.D.
Publisher: CRC Press
ISBN: 9780367399252
Category :
Languages : en
Pages : 528
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Book Description
Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.
Author: Kian Fan Chung
Publisher: European Respiratory Society
ISBN: 1849841047
Category : Medical
Languages : en
Pages : 360
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Book Description
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 848
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author:
Publisher:
ISBN: 9780429221095
Category : Allergy
Languages : en
Pages : 67
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Book Description
Author: Selda Pelin Kartal
Publisher: BoD – Books on Demand
ISBN: 9535131672
Category : Medical
Languages : en
Pages : 252
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Book Description
This book contains the latest advances and scientific knowledge from the leading experts in urticaria and angioedema. The book consists of 15 chapters in which urticaria classification, urticaria etiopathogenesis, urticaria clinics, urticarial syndromes, angioedemas, diagnosis, pathogenesis and pathophysiology of urticaria, and treatment options are discussed. This book also emphasizes on the various laboratory tests necessary for urticarias. One chapter of the book is devoted to comorbidities in chronic spontaneous urticaria. Another chapter is related with pathophysiology and treatment of hereditary angioedema. We are grateful to all the contributors and leading experts for their valuable chapters, which provide an in-depth view of all aspects of the content, backed with the most current literature in the field. We hope that this book will provide interesting knowledge and serve as a comprehensive guide to many physicians dealing with urticaria and angioedemas in their clinical practice.
Author: Robert Hnasko
Publisher: Humana
ISBN: 9781493927418
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume is a practical biochemical guide to the Enzyme-Linked Immunosorbent Assay (ELISA), used to detect a target substance in a liquid sample. The ELISA is an important and widely used diagnostic tool in medicine, animal health, botany and quality assurance processes in food and beverage production. An introductory chapter orients the reader on the basic structure and function of immunoglobulins and their fragments while subsequent chapters outline the methodology to generate monoclonal antibodies using hybridoma technology and the general methods used to purify antibodies. Multiple chapters demonstrate how to creatively use the properties of the antibody to identify, localize and quantify target analytes to answer questions and resolve problems. The reader will learn how to use a variety of immunoassay strategies, reporters and detection systems that will undoubtedly facilitate their efforts to gain answers to their own questions. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, ELISA: Methods and Protocols seeks to provide both professionals and novices with the technical information necessary for the reader to successfully use the immunoassay as part of the discovery process.
Author: Massoud Mahmoudi
Publisher: McGraw Hill Professional
ISBN: 0071593535
Category : Medical
Languages : en
Pages : 409
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Book Description
Clear, authoritative guidance for your day-to-day allergy and asthma practice Allergy and Asthma: Practical Diagnosis and Management is a concise guide that puts the most salient insights in allergy medicine right at your fingertips. Written by a leading allergy clinician, along with 30 nationally recognized expert contributors, this resource is perfect for front-line general practitioners, especially primary care physicians and allied health care providers. Inside, you'll find the most clinically relevant information on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders. Features Need-to-know coverage that spans the entire scope of adult allergy and asthma-geared for real world medical practice A timely look at occupational allergies and allergies linked to unhealthy environments Organization by specific organ, which guides you to diagnostic and therapeutic solutions quickly and easily Essential chapters on the principles of diagnosis and on medications used in the management of simple and complex allergy Coverage of new complementary and alternative medicine techniques in the management of allergic disorders Over 100 outstanding illustrations Key concepts, management protocols, and recent references that deliver s a highly accessible overview of today's allergy practice
