Hormonal Regulation of Mammary Tumor Virus Expression in Normal and Neoplastic Mouse Mammary Cells in Vitro PDF Download
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Author: Jason Yang
Publisher:
ISBN:
Category :
Languages : en
Pages : 154
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Author: Jason Yang
Publisher:
ISBN:
Category :
Languages : en
Pages : 154
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Author: Benjamin S. Leung
Publisher: Springer Science & Business Media
ISBN: 9401180458
Category : Medical
Languages : en
Pages : 296
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Book Description
The concept that hormones influence tumor growth originated in 1889 with the proposal of Albert Schinzinger who suggested that breast cancer is related to the ovaries. Several years later, Sir George Beatson observed that remission of disseminated breast cancer could be achieved in premenopausal patients by performing bilateral oophorectomy. As a result of the contri butions of Hedley Atkins, Charles Huggins and others, additive and ablative hormonal therapies have been widely used for the treatment of advanced breast cancers for several decades. Model systems to study the effects of hormones on growth and regression of breast tumors have been available for many years; however, the complexities of the hormonal environment have rendered in vivo studies difficult in man and experimental animals. Recently, the availability of long-term cultures of breast cancer cells has stimulated many investigators to use these cell lines to unravel the mechanisms of hormone action. Because of the extreme diversity and complexity of advances regarding the endocrinology of the breast and breast cancers, a multi-authored review was deemed necessary. It has been gratifying to receive contributions from many noted scholars. In Volume I of this monograph, the influence of steroid hormones and their antagonists upon normal and neoplastic tissues of the mammary gland are presented. In Volume II, the effects of peptide and other hormones are reviewed.
Author: E. Anderson
Publisher: Springer Science & Business Media
ISBN: 1461309433
Category : Science
Languages : en
Pages : 519
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Book Description
The idea for this book arose during the 1985 Gordon Conference on "Mammary Gland Biology". New developments in the methodology of cell biology and the explosive growth of molecular biology had begun to impact upon our understanding of mammary gland growth and function. It seemed a propitious time for summarizing the current status of knowledge of the cell and molecular biology of mammary cancer and for attempting to outline future areas of concern and interest. The reviews presented here were completed by the Fall of 1986. Although new insights will surely continue to emerge, it is hoped that the material in this volume will form not only a current update but a basic core of information for future experiments. We have not attempted to cover all areas of mammary gland transformation. Those areas where recent detailed reviews are already available have been omitted. Also, the areas of normal gland development, cell ultrastructure, hormone responsiveness, chemotherapy and clinical aspects of mammary cancer have not been included. Instead, we have selected those areas where the development of new methodology, reagents and results have led to new ideas about mammary gland function and development as they are related to neoplasia.
Author: Stuart Feinstein
Publisher:
ISBN:
Category : Chromatin
Languages : en
Pages : 318
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Author: Evelyn Mok-Lee
Publisher:
ISBN:
Category :
Languages : en
Pages : 230
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Author: Yuqian Zhou
Publisher:
ISBN:
Category :
Languages : en
Pages : 456
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Author: Benjamin S Leung
Publisher:
ISBN: 9789401180467
Category :
Languages : en
Pages : 300
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Author: Kiho Cho
Publisher:
ISBN:
Category :
Languages : en
Pages : 372
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Author: Michael James Brennan
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 432
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Author: Benjamin S. Leung
Publisher: Springer London
ISBN:
Category : Medical
Languages : en
Pages : 328
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