Author: James Graves Wilson
Publisher:
ISBN:
Category : Abnormalities, Human
Languages : en
Pages :
Book Description
Handbook of Teratology: Comparative, material, and epidemiologic aspects
Author: James Graves Wilson
Publisher:
ISBN:
Category : Abnormalities, Human
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category : Abnormalities, Human
Languages : en
Pages :
Book Description
HANDBOOK OF TERATOLOGY; Volume 3: Comparative, Maternal, and Epidemiologic Aspects
Author: JG WILSON (Ed)
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
VOL 1 GENERAL PRINCIPLES AND ETIOLOGY. VOL 2 MECHANISMS AND.
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
VOL 1 GENERAL PRINCIPLES AND ETIOLOGY. VOL 2 MECHANISMS AND.
Comparative, Maternal, and Epidemiologic Aspects
Author: James Wilson
Publisher: Springer
ISBN: 9780306362439
Category : Science
Languages : en
Pages : 360
Book Description
Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Publisher: Springer
ISBN: 9780306362439
Category : Science
Languages : en
Pages : 360
Book Description
Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Handbook of Teratology
Author: James Graves Wilson
Publisher:
ISBN:
Category :
Languages : en
Pages : 491
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 491
Book Description
HANDBOOK OF TERATOLOGY; Volume 1: General Principles and Etiology
Author: JG WILSON (Ed)
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
VOL 1 GENERAL PRINCIPLES AND ETIOLOGY. VOL 2 MECHANISMS AND PATHOGENESIS. VOL 3 COMPARATIVE, MATERNAL, AND EPIDEMIOLOGIC ASPECTS. VOL 4 RESEARCH PROCEDURES AND DATA ANALYSIS.
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
VOL 1 GENERAL PRINCIPLES AND ETIOLOGY. VOL 2 MECHANISMS AND PATHOGENESIS. VOL 3 COMPARATIVE, MATERNAL, AND EPIDEMIOLOGIC ASPECTS. VOL 4 RESEARCH PROCEDURES AND DATA ANALYSIS.
Handbook of Teratology: Research procedures and data analysis
Author: James Graves Wilson
Publisher:
ISBN:
Category : Abnormalities, Human
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category : Abnormalities, Human
Languages : en
Pages :
Book Description
Books in Print
Author:
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 1756
Book Description
Publisher:
ISBN:
Category : American literature
Languages : en
Pages : 1756
Book Description
Pediatric Annals
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 462
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 462
Book Description
Diet and Health
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765
Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Publisher: National Academies Press
ISBN: 0309039940
Category : Medical
Languages : en
Pages : 765
Book Description
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Catalog of Copyright Entries. Third Series
Author: Library of Congress. Copyright Office
Publisher: Copyright Office, Library of Congress
ISBN:
Category : Copyright
Languages : en
Pages : 1898
Book Description
Publisher: Copyright Office, Library of Congress
ISBN:
Category : Copyright
Languages : en
Pages : 1898
Book Description