Global Analysis of Splicing Perturbations in C.elegans Mec-8 and Sup-12 Mutant Strains During Development PDF Download
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Author: James Williams
Publisher:
ISBN:
Category :
Languages : en
Pages : 84
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Book Description
Author: James Williams
Publisher:
ISBN:
Category :
Languages : en
Pages : 84
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Book Description
Author: Donald L. Riddle
Publisher: Firefly Books
ISBN: 9780879695323
Category : Medical
Languages : en
Pages : 1252
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Book Description
Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309437873
Category : Science
Languages : en
Pages : 231
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Book Description
Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.
Author: William Barry Wood
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 694
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Book Description
Author: Serge Morand
Publisher: Springer Science & Business Media
ISBN: 9400721145
Category : Medical
Languages : en
Pages : 335
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Book Description
Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.
Author:
Publisher: Academic Press
ISBN: 9780123969682
Category : Science
Languages : en
Pages : 0
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Book Description
This new volume of Current Topics in Developmental Biology covers developmental timing, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as the timing of developmental programs in Drosophila, temporal patterning of neural progenitors, and environmental modulation of developmental timing.
Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416
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Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step
Author: Siegfried Hekimi
Publisher: Springer Science & Business Media
ISBN: 354048003X
Category : Science
Languages : en
Pages : 254
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Book Description
The molecular genetics of aging or life-span determination is an expanding field. One reason is because many people would consider it desirable if hu man life span could be extended. Indeed, it is difficult not to be fascinated by tales of the life and death of people who have succeeded in living a very long life. Because of this, we have placed at the head of this book the chapter by Perls et al. on Centenerians and the Genetics of Longevity. Perls and his coauthors convincingly argue that, while the average life expectancy might be mostly determined by environmental factors because the average person has an average genotype, extremely long life spans are genetically determined. Of course, studying humans to uncover the genetics of aging is not ideal, not so much because one cannot easily perform experiments as because they live such a long time. This is why most of this book describes the current state of research with model organisms such as yeast, worms, flies, and mice. J aswinski focuses on yeast and how metabolic activity and stress resistance affect the longevity of Saccharomyces cerevisiae. In the process, he discusses the concept of aging as applied to a unicellular organism such as yeast and the importance of metabolism and stress resistance for aging in all organisms.
Author: Jochen C. Rink
Publisher: Humana
ISBN: 9781493978007
Category : Science
Languages : en
Pages : 0
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Book Description
This volume explores the various facets of planaria as a biomedical model system and discusses techniques used to study the fascinating biology of these animals. The chapters in this book are divided into two parts: Part One looks at the biodiversity of planarian species, the molecular orchestration of regeneration, ecology of planarians in their natural habitats and their history as lab models. Part Two talks about experimental protocols for studying planarians, ranging from the establishment of a planarian research colony, to RNA and DNA extraction techniques, all the way to single stem cell transplantations or metabolomics analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Planarian Regeneration: Methods and Protocols is a valuable resource for both newcomers to the field and experts within established planarian laboratories.
Author: Sangeeta Saxena
Publisher: Springer
ISBN: 9811059845
Category : Science
Languages : en
Pages : 332
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Book Description
Begomoviruses are one of the most interesting plant viruses to study for basic and applied research as they cause huge economic losses to agriculture industries and farmers all over the world. They belong to family Geminiviridae and are emergent plant viral pathogens which cause diseases in various crops in the tropical and subtropical regions. They are transmitted by the whitefly (B. tabaci) and have either one (monopartite DNA-A) or two (bipartite DNA-A and DNA-B) genomic components. DNA-A and DNA-B are of ~2600 - 2800 nucleotides each. A number of serious diseases of cultivated crops of the Fabaceae, Malvaceae, Solanaceae and Cucurbitaceae families are caused by Begomoviruses which are considered as threat to their cultivation in many countries. Accurate diagnosis is important for successful diseases management, since plants infected by Begomovirus do not recover, suffer serious yield losses and act as further sources of inoculum, which is then picked up and spread by their vector whitefly (B. tabaci). Reports of occurrence of new viruses and re-emergence of several known viruses in new niches have become regular event. In such a dynamic system, growth of several crop species relies on an accurate diagnosis, management and better understanding of the biology of the casual virus. This is crucial to evolve appropriate control practices and to prevent the virus infection. Researchers have achieved considerable progress in characterization, detection and management of virus on different crop species in the last decade. This book covers latest information in diagnosis of begomoviruses in the present scenario and explores the new vistas in the field of genomics and proteomics. Chapters in Section 1 illustrates the occurrence, genome organisation, transmission and diagnostics of begomoviruses. It also details the diseases caused by begomoviruses on different crops, detection techniques and management strategies in support of research findings by presentation of data, graphics, figures and tables. Section 2 is a chapterwise collection of occurrence, diversity and status of begomoviruses in Asian Africa counties where the diseases are most prevalent. This book will provide wide opportunity to the readers to have complete information and status of begomovirus in Asia and Africa. This will be useful resource for researchers and extension workers involved in the begomvirus disease diagnosis and molecular biology. Expert detection, accurate diagnosis and timely management play a significant role in keeping plants free from pathogens. In this book expert researchers share their research knowledge and literature which are vital towards the diagnosis of begomoviruses, addressing traditional plant pathology techniques as well as advanced molecular diagnostic approach. The book deals with the economically important crops including fruits, vegetables along with challenges in crop protection against diseases caused by begomovirus. This will be resourceful and handy for researcher, practitioners and also students.
