Genetic and Molecular Analysis of Cell Fate Specification and Patterning in Caenorhabditis Elegans PDF Download
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Author: Xiaojun Zhao
Publisher:
ISBN:
Category :
Languages : en
Pages : 222
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Author: Xiaojun Zhao
Publisher:
ISBN:
Category :
Languages : en
Pages : 222
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Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Author:
Publisher: Academic Press
ISBN: 0080925189
Category : Technology & Engineering
Languages : en
Pages : 513
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Book Description
An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come. - Diverse, up-to-date techniques covered will be useful to the broadening community of C. elegans researchers for years to come - Chapters written by leaders in the field - Tried and true methods deliver busy researchers a one-stop compendium of essential protocols
Author: Judith Ann Austin
Publisher:
ISBN:
Category :
Languages : en
Pages : 304
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Author: Nikolaos Konstantinides
Publisher: Frontiers Media SA
ISBN: 2832513239
Category : Science
Languages : en
Pages : 159
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Author:
Publisher: Academic Press
ISBN: 0080859461
Category : Science
Languages : en
Pages : 687
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Book Description
The first of its kind, this laboratory handbook emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell,developmental, and molecular biology, as well as in genetics and pharmacology. Four primary sections--Genetic and Culture Methods, Neurobiology, Cell and Molecular Biology, and Genomics and Informatics--reflect the cross-disciplinary nature of C. elegans research. Because C. elegans is a simple and malleable organism with a small genome and few cell types, it provides an elegant demonstration of functions fundamental to multicellular organisms. The discipline has greatly expanded as researchers continue to find this small soil nematode to be the model of choice for studying specific pathways, stages of development, and cell types. By directing its audience not just to tried-and-true recipes for research, but also to databases and other innovative sources of information, this comprehensive collection is intended to guide investigators of C. elegans for years to come.First single-source book detailing explanations of current and classic C. elegans methodologiesDiversity and scope of techniques covered expected to be useful to the broadening community of C. elegans researchers for years to comeTechniques range from reverse genetics and mutagenesis, to laser ablation and electrophysiology, to in situ hybridization and DNA sequencing methodsAppendices include resource information important to the C. elegans community, including the C. elegans Genetics Center and Internet resources like the Worm Community System and ACeDBIllustrated with more than 100 tables and figures
Author: Ian A. Hope
Publisher: OUP Oxford
ISBN: 019159198X
Category : Science
Languages : en
Pages : 306
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Book Description
Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has recently taken on new importance with the publication of the entire genome sequence in 1998. The first chapter gives all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution. Information on how to obtain, grow, and maintain C. elegans for use as a model system is given in Chapter 4. Chapters 2 and 3 describe the genome project and show how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data. The next chapter gives the essential practical details of transformation and common uses for the technique. Chapter 6 covers reverse genetics and describes strategies for gene inactivation that are known to work in C elegans: epigenetic inactivation and mutational germ line inactivation. Chapter 7 is designed to help the user analyse phenotype by microscopy and includes Normaski, fluorescence, 4-dimensional, and electron microscopy. Techniques for studying the neurobiology of C. elegans are given in chapter 8. Chapter 9 describes the three commonly used approaches for studying gene expression and Chapter 10 deals with the common methods of molecular biology essential for gene characterization. C. elegans is not the ideal organism for biochemical studies, but chapter 11 describes several procedures for producing biochemically useful quantities of pure tissues. The final chapter is about conventional genetics and details the standard procedures for selfing and crossing; mutagenesis and mutant screening; characterization of mutants; gene mapping; temperature-shift experiments and mosaic analysis. Caenorhabditis Elegans: A Practical Approach will therefore provide all the background information necessary for use of C. elegans as a model system.
Author: Eric H. Davidson
Publisher: Elsevier
ISBN: 0080525598
Category : Science
Languages : en
Pages : 274
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Book Description
The interaction between biology and evolution has been the subject of great interest in recent years. Because evolution is such a highly debated topic, a biologically oriented discussion will appeal not only to scientists and biologists but also to the interested lay person. This topic will always be a subject of controversy and therefore any breaking information regarding it is of great interest.The author is a recognized expert in the field of developmental biology and has been instrumental in elucidating the relationship between biology and evolution. The study of evolution is of interest to many different kinds of people and Genomic Regulatory Systems: In Development and Evolution is written at a level that is very easy to read and understand even for the nonscientist.* Contents Include* Regulatory Hardwiring: A Brief Overview of the Genomic Control Apparatus and Its Causal Role in Development and Evolution * Inside the Cis-Regulatory Module: Control Logic and How the Regulatory Environment Is Transduced into Spatial Patterns of Gene Expression* Regulation of Direct Cell-Type Specification in Early Development* The Secret of the Bilaterians: Abstract Regulatory Design in Building Adult Body Parts* Changes That Make New Forms: Gene Regulatory Systems and the Evolution of Body Plans
Author:
Publisher: Academic Press
ISBN: 9780123969682
Category : Science
Languages : en
Pages : 0
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Book Description
This new volume of Current Topics in Developmental Biology covers developmental timing, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as the timing of developmental programs in Drosophila, temporal patterning of neural progenitors, and environmental modulation of developmental timing.
Author: Andrew Alan Papp
Publisher:
ISBN:
Category : Caenorhabditis elegans
Languages : en
Pages : 288
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Book Description
