Endorphins and Opiate Antagonists in Psychiatric Research PDF Download
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Author: Nandkumar S. Shah
Publisher: Springer Science & Business Media
ISBN: 1468411195
Category : Business & Economics
Languages : en
Pages : 490
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Book Description
The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux.
Author: Nandkumar S. Shah
Publisher: Springer Science & Business Media
ISBN: 1468411195
Category : Business & Economics
Languages : en
Pages : 490
Get Book Here
Book Description
The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux.
Author: 3Island Press
Publisher:
ISBN: 9781468411201
Category :
Languages : en
Pages : 512
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Book Description
Author: Earl Usdin
Publisher: Springer
ISBN: 1349040150
Category : Medical
Languages : en
Pages : 627
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Book Description
Author: Reginald Dean
Publisher: Springer Science & Business Media
ISBN: 1597451975
Category : Medical
Languages : en
Pages : 767
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Book Description
Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications
Author: Reginald Dean
Publisher: Humana Press
ISBN: 9781607612285
Category : Medical
Languages : en
Pages : 757
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Book Description
Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications
Author: E. Leong Way
Publisher: Pergamon
ISBN:
Category : Medical
Languages : en
Pages : 600
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Book Description
Author: Barry Stimmel
Publisher: Psychology Press
ISBN: 9780866563161
Category : Drug abuse
Languages : en
Pages : 120
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Book Description
This timely volume emphasizes the relevance of current, basic research to the clinical management of the substance abuser.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309459575
Category : Medical
Languages : en
Pages : 483
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Book Description
Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.
Author:
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 582
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Book Description
Author: Ernest L. Rossi
Publisher: W. W. Norton & Company
ISBN: 039331247X
Category : Psychology
Languages : en
Pages : 544
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Book Description
A remarkable collaboration between psychologist Rossi and gynecologist-obstetrician Cheek, this book guides and empowers therapists and patients to find the keys to their own health and well-being through therapeutic hypnosis. Hundreds of engaging case reports from Cheek's forty years of clinical work bring the theory of mind-body therapy to life, while Rossi's chapters link Cheek's often intuitive work to the latest research in psychobiology.
