Emerging Concepts on the NKG2D Receptor- NKG2D Ligand Axis in Health and Diseases

Emerging Concepts on the NKG2D Receptor- NKG2D Ligand Axis in Health and Diseases PDF Author: Nadia Guerra
Publisher: Frontiers Media SA
ISBN: 288963745X
Category :
Languages : en
Pages : 212

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Emerging Concepts on the NKG2D Receptor- NKG2D Ligand Axis in Health and Diseases

Emerging Concepts on the NKG2D Receptor- NKG2D Ligand Axis in Health and Diseases PDF Author: Nadia Guerra
Publisher: Frontiers Media SA
ISBN: 288963745X
Category :
Languages : en
Pages : 212

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Book Description


NK cell modifications to advance their anti-tumor activities

NK cell modifications to advance their anti-tumor activities PDF Author: Ye Li
Publisher: Frontiers Media SA
ISBN: 2832532845
Category : Medical
Languages : en
Pages : 198

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Book Description


Emerging Engineering Approaches in Cancer Immunotherapy

Emerging Engineering Approaches in Cancer Immunotherapy PDF Author: Xin Ming
Publisher: Frontiers Media SA
ISBN: 2832501605
Category : Medical
Languages : en
Pages : 205

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NK Cell Subsets in Health and Disease: New Developments

NK Cell Subsets in Health and Disease: New Developments PDF Author: Emanuela Marcenaro
Publisher: Frontiers Media SA
ISBN: 2889453502
Category :
Languages : en
Pages : 245

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Book Description
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation PDF Author: Gerard Socie
Publisher: Academic Press
ISBN: 0128134399
Category : Science
Languages : en
Pages : 450

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Book Description
Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications

The KIR Gene Cluster

The KIR Gene Cluster PDF Author: Mary Carrington
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer

Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer PDF Author: Loredana Cifaldi
Publisher: Frontiers Media SA
ISBN: 2889638766
Category :
Languages : en
Pages : 146

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Book Description
In this Research Topic, we would like to honor the memory of Prof. Vito Pistoia and pay tribute to his scientific contributions to the field of Cancer Immunity and Immunotherapy. Topic Editor Daniel Olive is the co-founder and shareholder of company Imcheck Therapeutics. All other topic editors declare no competing interests with regards to the Research Topic subject.

Targeting Key Cellular Signaling Network for Cancer Chemotherapy and Immunotherapy

Targeting Key Cellular Signaling Network for Cancer Chemotherapy and Immunotherapy PDF Author: Bo Zhai
Publisher: Frontiers Media SA
ISBN: 2832549241
Category : Medical
Languages : en
Pages : 261

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Book Description
The cellular signaling network refers to the complex system formed by the interactions between various signaling molecules and receptors within and between cells. It consists of multiple signaling pathways that mediate intricate cellular interactions both internally and externally. The development of cancer is closely associated with the intricate signaling transduction network within cells, where multiple signaling pathways are interconnected and collectively regulate the biological phenotypes of tumor cells.

Inflammation and Cancer

Inflammation and Cancer PDF Author: Bharat B. Aggarwal
Publisher: Springer
ISBN: 3034808372
Category : Medical
Languages : en
Pages : 489

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Book Description
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.