Contractile Systems in Non-muscle Tissues PDF Download
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Author: S. V. Perry
Publisher: North-Holland
ISBN:
Category : Science
Languages : en
Pages : 384
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Book Description
Author: S. V. Perry
Publisher: North-Holland
ISBN:
Category : Science
Languages : en
Pages : 384
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Book Description
Author: S. V. Perry
Publisher:
ISBN:
Category : Contractility (Biology)
Languages : en
Pages : 0
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Book Description
Author: S. V. Perry
Publisher:
ISBN:
Category :
Languages : en
Pages : 360
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Book Description
Author: S. V. Perry
Publisher:
ISBN:
Category :
Languages : nl
Pages : 360
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Book Description
Author: R. John Solaro
Publisher: Biota Publishing
ISBN: 1615041753
Category : Medical
Languages : en
Pages : 46
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Book Description
Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Lindsay Biga
Publisher:
ISBN: 9781955101158
Category :
Languages : en
Pages :
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Book Description
A version of the OpenStax text
Author: Emanuele E. Alia
Publisher: Greenwood
ISBN:
Category : Science
Languages : en
Pages : 760
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Book Description
Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309132991
Category : Business & Economics
Languages : en
Pages : 510
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Book Description
Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.
