Author: Andreas Ahlers
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ISBN:
Category :
Languages : en
Pages :
Book Description
Concise Total Synthesis of Enigmazole A & Studies Towards the Total Synthesis of Rhizoxin D
Author: Andreas Ahlers
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ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
The Total Synthesis of Rhizoxin D
Author: Kim Werner
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ISBN:
Category :
Languages : en
Pages : 312
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 312
Book Description
Total Synthesis of (+)-rhizoxin D.
Author: Jeffrey Paul Stonehouse
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Category :
Languages : en
Pages :
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ISBN:
Category :
Languages : en
Pages :
Book Description
Studies Directed Toward the Total Synthesis of (-)-enigmazole B
Author: Alia M. Orbin
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ISBN:
Category :
Languages : en
Pages : 247
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 247
Book Description
Total Synthesis of (-)-enigmazole A
Author: Yanran Ai
Publisher:
ISBN:
Category :
Languages : en
Pages : 530
Book Description
The dissertation contained herein presents a total synthesis of (-)-enigmazole A utilizing a late-stage large-fragment Petasis-Ferrier union/rearrangement protocol. Chapter One details the isolation, structural elucidation and subsequent biological studies of (-)-enigmazole A. The previous synthetic studies of (-)-enigmazole A are also introduced. The chapter then outlines the Smith three-step Petasis-Ferrier union/rearrangement protocol, as well as a number of the successfultotal syntheses achieved over the years by the Smith group utilizing this protocol. Herein, a late-stage large-fragment Petasis-Ferrier union/rearrangement will be utilized as the synthetic cornerstone for the Smith total synthesis of (-)-enigmazole A. Chapter Two describes the retrosynthetic strategy toward (-)-enigmazole A and subsequent total synthesis. The late-stage large-fragment Petasis-Ferrier union/rearrangement, which generates the entire carbon skeletonof (-)-enigmazole A, is described after the construction of the requisite eastern and western hemispheres. The chapter then describes the subsequent macrolactonization studies and the end game of the total synthesis. In addition to the Smith three-step Petasis-Ferrier union/rearrangement protocol, highlights of the total synthesis includes a Negishi cross-coupling, a dithiane-epoxide union, a Type I ARC multicomponent coupling, a Yamaguchi macrolactonization and chemoselective oxidation/reduction strategies the details of which are also described in Chapter Two.
Publisher:
ISBN:
Category :
Languages : en
Pages : 530
Book Description
The dissertation contained herein presents a total synthesis of (-)-enigmazole A utilizing a late-stage large-fragment Petasis-Ferrier union/rearrangement protocol. Chapter One details the isolation, structural elucidation and subsequent biological studies of (-)-enigmazole A. The previous synthetic studies of (-)-enigmazole A are also introduced. The chapter then outlines the Smith three-step Petasis-Ferrier union/rearrangement protocol, as well as a number of the successfultotal syntheses achieved over the years by the Smith group utilizing this protocol. Herein, a late-stage large-fragment Petasis-Ferrier union/rearrangement will be utilized as the synthetic cornerstone for the Smith total synthesis of (-)-enigmazole A. Chapter Two describes the retrosynthetic strategy toward (-)-enigmazole A and subsequent total synthesis. The late-stage large-fragment Petasis-Ferrier union/rearrangement, which generates the entire carbon skeletonof (-)-enigmazole A, is described after the construction of the requisite eastern and western hemispheres. The chapter then describes the subsequent macrolactonization studies and the end game of the total synthesis. In addition to the Smith three-step Petasis-Ferrier union/rearrangement protocol, highlights of the total synthesis includes a Negishi cross-coupling, a dithiane-epoxide union, a Type I ARC multicomponent coupling, a Yamaguchi macrolactonization and chemoselective oxidation/reduction strategies the details of which are also described in Chapter Two.
Studies Directed Towards the Total Synthesis of Rhizoxin
Author: Benjamin Eric Blass
Publisher:
ISBN:
Category :
Languages : en
Pages : 490
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 490
Book Description
Total Synthesis of (−)‐Enigmazole A.
Author:
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Category :
Languages : en
Pages :
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ISBN:
Category :
Languages : en
Pages :
Book Description
Studies Directed Toward the Total Synthesis of Rhizoxins
Author: Jian Hong
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ISBN:
Category :
Languages : en
Pages : 558
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 558
Book Description
Part A. Studies Directed Towards the Total Synthesis of (±) A-23187 ; Part B. Formal Total Synthesis of (±) A-23187
Author: Eric L. Williams
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ISBN:
Category : Organic compounds
Languages : en
Pages : 164
Book Description
Publisher:
ISBN:
Category : Organic compounds
Languages : en
Pages : 164
Book Description
Studies Towards the Total Synthesis of the Biologically Active Natural Product Aigialomycin D and Development of Two Novel Methodologies
Author: Naval Bajwa
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ISBN:
Category :
Languages : en
Pages : 674
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 674
Book Description