Computational And Mathematical Methods In Cardiovascular Physiology

Computational And Mathematical Methods In Cardiovascular Physiology PDF Author: Liang Zhong
Publisher: World Scientific
ISBN: 9813270659
Category : Medical
Languages : en
Pages : 458

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Book Description
Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Computational And Mathematical Methods In Cardiovascular Physiology

Computational And Mathematical Methods In Cardiovascular Physiology PDF Author: Liang Zhong
Publisher: World Scientific
ISBN: 9813270659
Category : Medical
Languages : en
Pages : 458

Get Book Here

Book Description
Cardiovascular diseases (CVD) including heart diseases, peripheral vascular disease and heart failure, account for one-third of deaths throughout the world. CVD risk factors include systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and diabetic status. Clinical trials have demonstrated that when modifiable risk factors are treated and corrected, the chances of CVD occurring can be reduced. This illustrates the importance of this book's elaborate coverage of cardiovascular physiology by the application of mathematical and computational methods.This book has literally transformed Cardiovascular Physiology into a STEM discipline, involving (i) quantitative formulations of heart anatomy and physiology, (ii) technologies for imaging the heart and blood vessels, (iii) coronary stenosis hemodynamics measure by means of fractional flow reserve and intervention by grafting and stenting, (iv) fluid mechanics and computational analysis of blood flow in the heart, aorta and coronary arteries, and (v) design of heart valves, percutaneous valve stents, and ventricular assist devices.So how is this mathematically and computationally configured landscape going to impact cardiology and even cardiac surgery? We are now entering a new era of mathematical formulations of anatomy and physiology, leading to technological formulations of medical and surgical procedures towards more precise medicine and surgery. This will entail reformatting of (i) the medical MD curriculum and courses, so as to educate and train a new generation of physicians who are conversant with medical technologies for applying into clinical care, as well as (ii) structuring of MD-PhD (Computational Medicine and Surgery) Program, to train competent medical and surgical specialists in precision medical care and patient-specific surgical care.This book provides a gateway for this new emerging scenario of (i) science and engineering based medical educational curriculum, and (ii) technologically oriented medical and surgical procedures. As such, this book can be usefully employed as a textbook for courses in (i) cardiovascular physiology in both the schools of engineering and medicine of universities, as well as (ii) cardiovascular engineering in biomedical engineering departments worldwide.

Mathematical Modeling and Validation in Physiology

Mathematical Modeling and Validation in Physiology PDF Author: Jerry J. Batzel
Publisher: Springer
ISBN: 3642328822
Category : Mathematics
Languages : en
Pages : 270

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Book Description
This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.

Mathematical Modelling of the Human Cardiovascular System

Mathematical Modelling of the Human Cardiovascular System PDF Author: Alfio Quarteroni
Publisher: Cambridge University Press
ISBN: 110848039X
Category : Mathematics
Languages : en
Pages : 291

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Book Description
Addresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.

Mathematical and Computational Methods in Physiology

Mathematical and Computational Methods in Physiology PDF Author: L. Fedina
Publisher: Elsevier
ISBN: 1483190226
Category : Science
Languages : en
Pages : 352

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Book Description
Mathematical and Computational Methods in Physiology discusses the importance of quantitative description of physiological phenomena and for quantitative comparison of experimental data. An article explains the homeostasis of the body with a focus on the controlling aspects. This section evaluates the concepts of modern physiology and biocybernetics. The canal-ocular reflex and the otolith-ocular reflex in man stimulates eye rotations compensatory for head angular and linear displacements. The book enumerates some modelling and simulation to observe the visual-vestibular interaction during angular and linear body acceleration. A section on the determination of cardiovascular control is given. The text reviews the mathematical models of the biological age of the rat. A numerical simulation of water transport in epithelial junctions is explained comprehensively. A chapter analyzing the computer simulation of drug-receptor interaction is presented. The book will provide useful information to zoologists, doctors, ophthalmologists, students and researchers in the field of medicine.

Cardiovascular Mathematics

Cardiovascular Mathematics PDF Author: Luca Formaggia
Publisher: Springer Science & Business Media
ISBN: 8847011523
Category : Mathematics
Languages : en
Pages : 528

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Book Description
Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

Computational Methods in Cardiac Electrophysiology

Computational Methods in Cardiac Electrophysiology PDF Author: Matthijs Cluitmans
Publisher: Frontiers Media SA
ISBN: 2832529259
Category : Science
Languages : en
Pages : 229

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Book Description


Applications

Applications PDF Author: Peter Benner
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110497751
Category : Mathematics
Languages : en
Pages : 584

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Book Description
An increasing complexity of models used to predict real-world systems leads to the need for algorithms to replace complex models with far simpler ones, while preserving the accuracy of the predictions. This three-volume handbook covers methods as well as applications. This third volume focuses on applications in engineering, biomedical engineering, computational physics and computer science.

Biology and Mechanics of Blood Flows

Biology and Mechanics of Blood Flows PDF Author: Marc Thiriet
Publisher: Springer Science & Business Media
ISBN: 0387748490
Category : Science
Languages : en
Pages : 468

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Book Description
This authoritative book presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. This volume contains chapters on anatomy, physiology, continuum mechanics, as well as pathological changes in the vasculature walls including the heart and their treatments. Methods of numerical simulations are given and illustrated in particular by application to wall diseases.

Biomedical Engineering of Pancreatic, Pulmonary, and Renal Systems, and Applications to Medicine

Biomedical Engineering of Pancreatic, Pulmonary, and Renal Systems, and Applications to Medicine PDF Author: Dhanjoo N. Ghista
Publisher: Elsevier
ISBN: 0323958850
Category : Science
Languages : en
Pages : 756

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Book Description
Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems. - Covers foundational concepts of the emerging fields of quantitative physiology and computational medicine, developing the biomedical engineering modeling of three important organ systems: pancreas, lungs, and kidneys - Provides readers with detailed understanding of novel biomedical engineering strategies in key areas, such as pancreatic system engineering, glucose-insulin regulatory system engineering, pulmonary system engineering, and renal system engineering - Provides in-depth technical coverage of computational modeling techniques and applied mathematics for these important physiological systems, including differential equations and the associated MATLAB datasets for all applied diagnostic and treatment examples

Computational Hemodynamics – Theory, Modelling and Applications

Computational Hemodynamics – Theory, Modelling and Applications PDF Author: Jiyuan Tu
Publisher: Springer
ISBN: 9401795940
Category : Technology & Engineering
Languages : en
Pages : 360

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Book Description
This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book’s approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.