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Author: Harry Brown
Publisher: Elsevier
ISBN: 0323154581
Category : Science
Languages : en
Pages : 353
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Book Description
Chemistry of the Cell Interface discusses reactions involving the cells structured elements and interfacial reaction systems, which are extrapolations from the conventional methodology of solution biochemistry. The contributions to this two-volume book deal with the relationship of structure to biochemical reactions. Part A (Chapters I-V) deals with the components of complex subcellular systems, in vitro interface relationships model for lipid-lipid and lipid-protein interactions, and reaction model for chemical phenomena in systems having restricted degrees of freedom. Part B (Chapters VI-VIII) covers waters contributions to the reaction systems, the consideration of modified proteins as model reactants, and the aspects of protein chemistry pertinent to the design of interface experimental systems. The book is suited for readers who wish to broaden their understanding in interface chemistry within the biological cell.
Author: Harry Brown
Publisher: Elsevier
ISBN: 0323154581
Category : Science
Languages : en
Pages : 353
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Book Description
Chemistry of the Cell Interface discusses reactions involving the cells structured elements and interfacial reaction systems, which are extrapolations from the conventional methodology of solution biochemistry. The contributions to this two-volume book deal with the relationship of structure to biochemical reactions. Part A (Chapters I-V) deals with the components of complex subcellular systems, in vitro interface relationships model for lipid-lipid and lipid-protein interactions, and reaction model for chemical phenomena in systems having restricted degrees of freedom. Part B (Chapters VI-VIII) covers waters contributions to the reaction systems, the consideration of modified proteins as model reactants, and the aspects of protein chemistry pertinent to the design of interface experimental systems. The book is suited for readers who wish to broaden their understanding in interface chemistry within the biological cell.
Author: Harry Brown
Publisher: Elsevier
ISBN: 032315526X
Category : Science
Languages : en
Pages : 340
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Book Description
Chemistry of the Cell Interface, Part B deals with the relationship of structure to biochemical reactions. This book is divided into three chapters. Chapter VI focuses on the water's contribution to the reaction systems, emphasizing the nature of the cell's aqueous phases. The matrix-supported enzymes, technology of the model, and properties of enzymes bound to polymeric matrices that have been contrasted with solution and membrane particle systems are elaborated in Chapter VII. The last chapter focuses on the aspects of protein chemistry pertinent to the design of interface experimental systems. Other topics include the structure of water near interfaces, functional role of water in biological systems, and adsorbed and ionically bonded enzymes. The enzymes insolubilized by the use of bridging compounds and changes in protein conformation associated with chemical modification are likewise covered in this text. This publication is a good source for morphologists, chemists, and specialists of disciplines related to the chemistry of cell interface.
Author: Edward Bittar
Publisher: Elsevier
ISBN: 0080528767
Category : Science
Languages : en
Pages : 397
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Book Description
This is the first of a 4-volume module that is an introduction to the study of cell chemistry and physiology. It is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are central to an understanding of cell biology and those that are certain to become of increasing importance in the teaching of modern medicine.We have followed what appeared to as to be the logical divisions of the subject beginning with proteins. Allewell and her colleagues stress the point that proteins fold spontaneously to form complex three-dimensional structures and that some of them unfold with the help of proteins called chaperones. Michaelis-Menten kinetics are shown by Nelsestuen to describe the behaviour of enzymes in the test tube. The formalism is particularly useful in the search for agents of therapeutic value, as exemplified by methotrexate. Uptake by mammalian cells of substrates and their metabolic conversions are discussed by van der Vusse and Reneman. However, both Welch and Savageau expound the view that the cell is not simply a bagful of enzymes. The biologist is urged by Savageau to abandon Michaelis-Menten formalism and apply the Power Law. The biologist is also told that the approach to arriving at a theory of metabolic control would have to be one of successive approximations requiring the use of the computer. Information gained from comparative biochemistry is shown by Storey and Brooks to have shed new light on mechanisms of metabolic rate depression and freeze tolerance, and to be applicable to organ transplantation technology. We are reminded that enzyme adaptation is partly the result of the presence of a hydrating shell of vicinal water that stabilises conformation of the enzyme. Vicinal water, according to Drost-Hausen and Singleton, lies adjacent to most solids and protein interfaces. The kinks or breaks observed in the slope of the Arrhenius plot are attributed to structural changes in vicinal water. Regulation of cell volume is shown by Hempling to involve regulation of cell water. It could be that the osmo-receptor or volume detection system is a protein that links the cytoskeleton to specific K and C1 channels. Additionally, it is interesting that aquaporins, which are water channel-forming membrane proteins, are now known to exist in both renal and extra-renal tissues. One of the renal porins is affected by vasopressin. We then pass on to protein synthesis (Rattan) and other important topics including protein glycosylation (Hounsell), methylation (Clarke), ADP-ribosylation (Pearson) and prenylation (Gelb). Among the four types of lipids attached to membrane proteins are the prenyl groups. Ford and Gross in their chapter on lipobiology drive home the point that there is an accumulation of acyl carnitine and lysophospholipids during myocardial infarction.
Author: Harry Darrow Brown
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 352
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Book Description
Chemistry of the Cell Interface Part A ...
Author: Nihal Engin Vrana
Publisher: CRC Press
ISBN: 135183097X
Category : Technology & Engineering
Languages : en
Pages : 247
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Book Description
A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro. Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering.
Author: William Alfred Adams
Publisher:
ISBN:
Category : Electrolytes
Languages : en
Pages : 544
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Book Description
Author: O.L. Lange
Publisher: Springer Science & Business Media
ISBN: 3642664296
Category : Science
Languages : en
Pages : 554
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Book Description
Author: H.T. Tien †
Publisher: Elsevier
ISBN: 0080536166
Category : Technology & Engineering
Languages : en
Pages : 651
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Book Description
This book summarizes the current status of research on bilayer lipid membranes (planar lipid bilayers and spherical liposomes). In addition to describing the properties of lipid bilayers and examining biomembrane phenomena, the book has two other objectives. The first is to present practical methods for the formation and study of lipid bilayers with either aqueous or metal-lipid bilayer interfaces. The second aim is to treat planar lipid bilayers as a new type of interfacial adsorption phenomena. The first nine chapters cover properties of biomembranes, basic principles of membrane biophysics, transport, electrochemistry, physiology, bioenergetics, and photobiology. Chapter 10 presents the following topics: lipid bilayers in medicine, supported lipid bilayers as sensors, a short discussion of liposomes, and solar energy transduction via semiconductor septum photovoltaic cells based on natural photosynthesis.
Author: Isidore Gersh
Publisher: Elsevier
ISBN: 0323158625
Category : Science
Languages : en
Pages : 264
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Book Description
Submicroscopic Cytochemistry, Volume II: Membranes, Mitochondria, and Connective Tissues presents laboratory findings and theoretical aspects of the cytochemistry of cellular membranes, mitochondria, and connective tissues. Emphasis is on the molecular and macromolecular organization of cellular membranes, along with the origin and distribution of the major macromolecular aggregates of connective tissue. This volume consists of 11 chapters and begins by discussing the results of cytochemical studies on lipid and protein components of membranes in acinar and hepatic cells of the murine pancreas. The following chapters focus on densitometric studies of lipid membranes in pancreatic acinar cells of the mouse; the distribution of lipids and proteins in mitochondria of hepatic and exocrine pancreatic cells of adult mice, and of nucleic acids in mitochondria of embryonic cells; and possible precursor granules in fibroblasts, chondrocytes, and osteoblasts. The distribution of DNA and of soluble and insoluble RNAs in chondrocytes of the epiphyseal plate of the rat tibia is also examined, along with vascularity in tendons of young rats. This monograph will be of interest to cytochemists, biochemists, and molecular biologists.
Author: Ashutosh Tiwari
Publisher: John Wiley & Sons
ISBN: 1119242746
Category : Technology & Engineering
Languages : en
Pages : 528
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Book Description
Advanced Material Interfaces is a state-of-the-art look at innovative methodologies and strategies adopted for interfaces and their applications. The 13 chapters are written by eminent researchers not only elaborate complex interfaces fashioned of solids, liquids, and gases, but also ensures cross-disciplinary mixture and blends of physics, chemistry, materials science, engineering and life sciences. Advanced interfaces operate fundamental roles in essentially all integrated devices. It is therefore of the utmost urgency to focus on how newly-discovered fundamental constituents and interfacial progressions can be materialized and used for precise purposes. Interfaces are associated in wide multiplicity of application spectrum from chemical catalysis to drug functions and the advancement is funnelled by fine-tuning of our fundamental understanding of the interface effects.
