Biology and Pathology of Perineuronal Satellite Cells in Sensory Ganglia PDF Download
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Author: Ennio Pannese
Publisher: Springer
ISBN: 3319601407
Category : Medical
Languages : en
Pages : 83
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Book Description
This volume provides a comprehensive and updated review of perineuronal satellite cells in sensory ganglia. For a long time since their discovery by Valentin in the first half of the 19th century these cells received only modest attention. However, some years ago research findings suggested that satellite cells play a role in the development and maintenance of neuropathic pain. As a result, satellite cells are now considered as possible targets for neuropathic pain treatment. Thus, interest in satellite cells has burgeoned. The review is based on the author’s own work as well as on his critical evaluation and systematic arrangement of data scattered through a large number of research papers. The following aspects of perineuronal satellite cells are covered: Shape and structure; molecular characteristics; origin and development; biological and functional properties; relationships with the ganglion sensory neuron; age-related changes; roles under physiological conditions; reactions to experimental and pathological conditions; role in neuropathic pain.
Author: Ennio Pannese
Publisher: Springer
ISBN: 3319601407
Category : Medical
Languages : en
Pages : 83
Get Book Here
Book Description
This volume provides a comprehensive and updated review of perineuronal satellite cells in sensory ganglia. For a long time since their discovery by Valentin in the first half of the 19th century these cells received only modest attention. However, some years ago research findings suggested that satellite cells play a role in the development and maintenance of neuropathic pain. As a result, satellite cells are now considered as possible targets for neuropathic pain treatment. Thus, interest in satellite cells has burgeoned. The review is based on the author’s own work as well as on his critical evaluation and systematic arrangement of data scattered through a large number of research papers. The following aspects of perineuronal satellite cells are covered: Shape and structure; molecular characteristics; origin and development; biological and functional properties; relationships with the ganglion sensory neuron; age-related changes; roles under physiological conditions; reactions to experimental and pathological conditions; role in neuropathic pain.
Author: Ennio Pannese
Publisher: Springer Science & Business Media
ISBN: 3642677509
Category : Medical
Languages : en
Pages : 122
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Book Description
The earliest mention of a cell sheath enveloping the body of the neurons in sensory ganglia is probably the following description by Valentin: "Sowohl die Kugeln der Be legungsformation 1, als die Primitivfasem, werden von eigenthi. imlichen, sie isolirenden Scheiden umgeben, welche aile Stufen der Dicke von einer fast gar nicht mehr wahr nehrnbaren Zartheit bis zu einer ziemlich bedeutenden Starke durchlaufen. Diese Hill len sind aber immer zellgewebeartiger Natur" (1836, p 162). In some illustrations of the above mentioned paper the nuclei of the satellite cells adjacent to the surface of the nerve cell body, both in the trigeminal ganglion and in the ganglia of the vegeta tive nervous system, are clearly shown (Fig. lA). The author, however, miSinterpreted these nuclei as pigment granules (Pigmentkorperchen). A little later, Remak (1838) denied the existence of the perineuronal cell sheath. This prompted a ready reply from Valentin (1839), who offered a more detailed description of the perineuronal cell sheath, illustrated it with new drawings (Fig. IB), and gave a correct interpreta tion of the nuclei. In fact, he wrote: Fig. lA-B. Nerve cell bodies of sympathetic ganglia with the nuclei of the satellite cells on the neuronal surface. Redrawn from Valentin; A, 1836; B, 1839.
Author: Jahangir Moini
Publisher: Academic Press
ISBN: 0128217553
Category : Medical
Languages : en
Pages : 554
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Book Description
Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others Includes full color figures, photos, tables, graphs and radioimaging Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Author: Abraham L Kierszenbaum
Publisher: Elsevier Health Sciences
ISBN: 0323313353
Category : Medical
Languages : en
Pages : 749
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Book Description
Fully integrating histology, cell biology, and pathology, the 4th Edition of the award-winning Histology and Cell Biology: An Introduction to Pathology presents key concepts in an understandable, easy-to-digest manner. Authors Abraham L. Kierszenbaum, MD, PhD and Laura L. Tres MD, PhD link basic science to clinical application throughout, focusing on what you need to know for your coursework now – and how to apply that information in a clinical setting . Full-color illustrations, as well as unique, student-friendly features, help you quickly grasp the complexities of pathologic abnormalities. Consult this title on your favorite e-reader. Get a contemporary, integrated approach to basic science and clinical knowledge, as well as histology, cell biology, and pathology with Dr. Kierszenbaum’s ground-breaking text. Clearly visualize challenging concepts with the aid of vivid, full-color illustrations, diagrams, photomicrographs, and pathology photos – all fully integrated on every page of the text. Grasp key information quickly thanks to highlighted key clinical terms, clinical conditions boxes, and Essential Concepts boxes at the end of every chapter. Find clinically relevant material fast with a detailed table of contents that highlights all clinical examples in red. Understand the links between chapter concepts with new concept mapping animations – an outstanding supplement to in-class instruction.
Author: Ennio Pannese
Publisher: Springer
ISBN: 3319068563
Category : Medical
Languages : en
Pages : 329
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Book Description
During the second half of the 20th century, the introduction of a variety of new techniques greatly expanded our knowledge of the structure of nerve and neuroglial cells and of the organization of the nervous system at the cellular level. This new information has, however, generally been scattered throughout the literature, making it difficult for investigators to gain an overall vision of the discipline. The author has marshalled these scattered data to provide a systematic overview of the field placed within a historical context. He has correlated the major new findings with the classical notions of light microscopy and has integrated them with elements of biochemistry and cell physiology. After the publication of the first edition, the introduction of new microscopies and especially the growth of molecular biology have greatly expanded our knowledge, in particular on the intercellular communication in the nervous system and on the roles of neuroglial cells. These achievements have made a second edition of the book necessary. The fully revised and updated text, together with unique high-quality illustrations of structures of the central and peripheral nervous system, ensure that this new edition will be invaluable for neuroscientists, particularly those involved in cellular neuropathology, neurochemistry, neurophysiology and molecular neurobiology.
Author: Mark R. Wick
Publisher: Cambridge University Press
ISBN: 9781107022836
Category : Medical
Languages : en
Pages : 0
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Book Description
Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.
Author: Alexander Y. Shin
Publisher: Springer Nature
ISBN: 3030695174
Category : Medical
Languages : en
Pages : 644
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Book Description
Fully illustrated and enhanced with accompanying video clips, this comprehensive text presents the clinical evaluation and management of brachial plexus injuries and reconstruction, both for adult patients and birth injuries. Divided into two main sections, part one covers adult brachial plexus injuries, discussing the relevant anatomy and biology, epidemiology, and associated injuries. The main focus, however, is on diagnosis – the clinical exam as well as neurodiagnostic and radiographic evaluation – and surgical management approaches and techniques, including nerve grafting and transfers, tendon and muscle transfers, and joint fusion. Related topics are presented in chapters on sensory reinnervation, neuropathic pain management, the role of amputation and prosthetics, and pre- and post-surgical therapy protocols. Brachial plexus birth injury is described in part two, also focusing mainly on diagnosis and management but with an emphasis on the fact that babies are not small adults and special considerations are warranted. This section concludes with chapters on the management of late complications and long-term sequelae. A comprehensive surgical text on brachial plexus injuries has not been previously attempted. Filling a large gap in the literature, Operative Brachial Plexus Surgery is the go-to resource for adult and birth related brachial plexus reconstruction for orthopedic surgeons, neurosurgeons, plastics surgeons, and their trainees.
Author: Runjan Chetty
Publisher: Cambridge University Press
ISBN: 1316592065
Category : Medical
Languages : en
Pages : 525
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Book Description
Providing a unique A-Z guide to antibodies for immunohistology, this is an indispensable source for pathologists to ensure the correct application of immunohistochemistry in daily practice. Each entry includes commercial sources, clones, descriptions of stained proteins/epitopes, the full staining spectrum of normal and tumor tissues, staining pattern and cellular localization, the range of conditions of immunoreactivity, and pitfalls of the antibody's immunoprofile, giving pathologists a truly thorough quick-reference guide to sources, preparation and applications of specific antibodies. Appendices provide useful quick-reference tables of antibody panels for differential diagnoses, as well as summaries of diagnostic applications. Expanded from previous editions with over forty new entries, this handbook for diagnostic, therapeutic, prognostic and research applications of antibodies is an essential desktop book for practicing pathologists as well as researchers, residents and trainees.
Author: Nicole Le Douarin
Publisher: Cambridge University Press
ISBN: 9780521620109
Category : Medical
Languages : en
Pages : 494
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Book Description
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
Author: Wolfgang Kühnel
Publisher: Thieme
ISBN: 9781588901750
Category : Medical
Languages : en
Pages : 548
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Book Description
This timeless pocket atlas is the ideal visual companion to histology and cytology textbooks. First published in 1950 and translated into eight languages, Kuehnel's Pocket Atlas of Cytology, Histology and Microscopic Anatomy is a proven classic. The fully revised and updated fourth edition contains 745 full-color illustrations - almost 200 more than were included in the third edition. Superb, high-quality microphotographs and pathologic stains are accompanied by legends, informative texts, and numerous cross-references. Key features of the updated fourth edition: More than 700 high-quality illustrations using advanced techniques in histology and electron microscopy Practical, information Concise and focused text Key concepts and ideas illustrated in less than 550 pages Ideal for exam preparation, this world-class book is an indispensable visual study tool for medical, dental and biology students. It can also serve as an outstanding review and refresher text.
