Biochemical Analysis of the Ligand Binding Domain of the LDL Receptor PDF Download
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Author: Elizabeth Jaffe
Publisher:
ISBN:
Category : Ligand binding (Biochemistry)
Languages : en
Pages : 176
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Book Description
Author: Elizabeth Jaffe
Publisher:
ISBN:
Category : Ligand binding (Biochemistry)
Languages : en
Pages : 176
Get Book Here
Book Description
Author: J. Robin Harris
Publisher: Springer Science & Business Media
ISBN: 9048186226
Category : Science
Languages : en
Pages : 641
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Book Description
Knowledge of cholesterol and its interaction with protein molecules is of fundamental importance in both animal and human biology. This book contains 22 chapters, dealing in depth with structural and functional aspects of the currently known and extremely diverse unrelated families of cholesterol-binding and cholesterol transport proteins. By drawing together this range of topics the Editor has attempted to correlate this broad field of study for the first time. Technical aspects are given considerable emphasis, particularly in relation cholesterol reporter molecules and to the isolation and study of membrane cholesterol- and sphingomyelin-rich "raft" domains. Cell biological, biochemical and clinical topics are included in this book, which serve to emphasize the acknowledged and important benefits to be gained from the study of cholesterol and cholesterol-binding proteins within the biomedical sciences and the involvement of cholesterol in several clinical disorders. It is hoped that by presenting this topic in this integrated manner that an appreciation of the fact that there is much more that needs to be taken into account, studied and understood than the widely discussed "bad and good cholesterol" associated, respectively, with the low- and high-density lipoproteins, LDL and HDL.
Author: Dennis E. Vance
Publisher: Elsevier
ISBN: 9780444511393
Category : Medical
Languages : en
Pages : 644
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Book Description
The first edition of this book was published in 1985. The content of the 4th edition reflects the enormous advances that have occurred since that time in the field of lipid biochemistry. This publication is unique in that it represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs. The book is not a collection of exhaustive reviews, but a current and readable summary of diverse aspects of lipids. It is intended as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry and will also serve as a general reference book for scientists studying lipids, lipoproteins and membranes.
Author: Neale Ridgway
Publisher: Elsevier
ISBN: 0080559883
Category : Science
Languages : en
Pages : 653
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Book Description
Research on the biochemistry and molecular biology of lipids and lipoproteins has experienced remarkable growth in the past 20 years, particularly with the realization that many different classes of lipids play fundamental roles in diseases such as heart disease, obesity, diabetes, cancer and neurodegenerative disorders. The 5th edition of this book has been written with two major objectives. The first objective is to provide students and teachers with an advanced up-to-date textbook covering the major areas of current interest in the lipid field. The chapters are written for students and researchers familiar with the general concepts of lipid metabolism but who wish to expand their knowledge in this area. The second objective is to provide a text for scientists who are about to enter the field of lipids, lipoproteins and membranes and who wish to learn more about this area of research. All of the chapters have been extensively updated since the 4th edition appeared in 2002. - Represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs - Allows scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances - Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry
Author: Karen Gray Ruelle
Publisher:
ISBN: 9780439271455
Category : Snow
Languages : en
Pages : 0
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Book Description
Harry and his sister Emily want to make an original valentine for their parents but cannot seem to find the right idea, until a surprise snowstorm inspires them.
Author: J.E. Vance
Publisher: Elsevier
ISBN: 008086080X
Category : Science
Languages : en
Pages : 619
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Book Description
The second edition of this book on lipids, lipoprotein and membrane biochemistry has two major objectives - to provide anadvanced textbook for students in these areas of biochemistry,and to summarise the field for scientists pursuing research inthese and related fields. Since the first edition of this book was published in 1985 theemphasis on research in the area of lipid and membrane biochemistry has evolved in new directions. Consequently, thesecond edition has been modified to include four chapters on lipoproteins. Moreover, the other chapters have been extensivelyupdated and revised so that additional material covering the areas of cell signalling by lipids, the assembly of lipids andproteins into membranes, and the increasing use of molecular biological techniques for research in the areas of lipid, lipoprotein and membrane biochemistry have been included. Each chapter of the textbook is written by an expert in the field, but the chapters are not simply reviews of current literature. Rather, they are written as current, readable summaries of these areas of research which should be readily understandable to students and researchers who have a basic knowledge of general biochemistry. The authors were selected fortheir abilities both as researchers and as communicators. In addition, the editors have carefully coordinated the chapters sothat there is little overlap, yet extensive cross-referencing among chapters.
Author: Sho Yamasaki
Publisher: Springer
ISBN: 4431560157
Category : Medical
Languages : en
Pages : 213
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Book Description
The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.
Author: Arnold von Eckardstein
Publisher: Springer
ISBN: 9783319096643
Category : Medical
Languages : en
Pages : 0
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Book Description
In this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts of therapeutic exploitation. The book is of interest to researchers in academia and industry focusing on lipoprotein metabolism, cardiovascular diseases and immunology as well as clinical pharmacologists, cardiologists, diabetologists, nephrologists and other clinicians interested in metabolic or inflammatory diseases.
Author: William Lennarz
Publisher: Springer Science & Business Media
ISBN: 1468410067
Category : Science
Languages : en
Pages : 391
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Book Description
Although glycoproteins and proteoglycans have been a subject of re search for many years, it is only during the last five or so years that they have aroused the interest of a very broad cross section of investigators in the biological sciences. The reason for this expanded interest in these molecules is simple: not only are glycoproteins and proteoglycans ubiq uitous, but many are molecules with well-defined and important biological functions. The list of molecules that fall into this category grows daily; interferon, immunoglobulins, certain hormones, many cell surface recep tors, and viral coat proteins are but a few examples. Thus, investigators with interests as diverse as viral replication. cell-cell interactions. poly isoprenoid synthesis, secretory processes, hormone responses, embryonic development, and immunology have become concerned with glycopro teins and proteoglycans. The objective of this book is to summarize the current state of knowledge on the biochemistry of these molecules. Coverage is by no means encyclopedic; rather the thrust is to emphasize the recent ad vances. The first chapter deals primarily with structural work on the oligosaccharide chains of glycoproteins, but it will be apparent in it and in the succeeding two chapters on biosynthesis that not only do structural studies aid biosynthetic investigations, but that studies on biosynthesis often playa major role in elucidation of structure.
Author: B.B. Biswas
Publisher: Springer Science & Business Media
ISBN: 1489917276
Category : Science
Languages : en
Pages : 451
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Book Description
Here, researchers review the latest breakthroughs in protein research. Their contributions explore emerging principles and techniques and survey important classes of proteins that will play key roles in the field's future. Articles examine the possibility of a Boltzman-like distribution in protein substructures, the new technique of Raman spectroscopy, and compact intermediate states of protein folding. This well-illustrated volume also features coverage of proteins that bind nucleic acids.
