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Author: Tahany Elias
Publisher: LAP Lambert Academic Publishing
ISBN: 9783844392906
Category :
Languages : en
Pages : 112
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Book Description
Obesity is a condition in which excess body fat may put a person at the risk of developing insulin resistance and type 2 diabetes mellitus. With the growing prevalence of obesity, scientific interest in the biology of adipose tissue [which is the body's largest reserve of fuel] has been extended to the secretory products of adipocytes. In recent years, a line of evidence has demonstrated a much more complex function of adipose tissue, as an endocrine organ that releases hormones into the blood stream to take part in their potential implication in insulin resistance, obesity and diabetes. These adipocytes' specific proteins include adiponectin, leptin and resistin. This study aimed to assess the effect of modest weight loss on serum adipocytokines' changes and hence discover their role as a link between obesity and insulin resistance diabetes.
Author: Tahany Elias
Publisher: LAP Lambert Academic Publishing
ISBN: 9783844392906
Category :
Languages : en
Pages : 112
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Book Description
Obesity is a condition in which excess body fat may put a person at the risk of developing insulin resistance and type 2 diabetes mellitus. With the growing prevalence of obesity, scientific interest in the biology of adipose tissue [which is the body's largest reserve of fuel] has been extended to the secretory products of adipocytes. In recent years, a line of evidence has demonstrated a much more complex function of adipose tissue, as an endocrine organ that releases hormones into the blood stream to take part in their potential implication in insulin resistance, obesity and diabetes. These adipocytes' specific proteins include adiponectin, leptin and resistin. This study aimed to assess the effect of modest weight loss on serum adipocytokines' changes and hence discover their role as a link between obesity and insulin resistance diabetes.
Author: Giamila Fantuzzi
Publisher: Springer Science & Business Media
ISBN: 1597453706
Category : Medical
Languages : en
Pages : 397
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Book Description
This book presents a comprehensive survey of adipose tissue, its physiological functions, and its role in disease. The volume spans the entire range of adipose tissue studies, from basic anatomical and physiological research to epidemiology and clinical studies. Groundbreaking recent studies are incorporated into traditional models of adipose tissue properties. A description of the role of macrophages in obesity and metabolism in included.
Author: Ayse Basak Engin
Publisher: Springer
ISBN: 331948382X
Category : Science
Languages : en
Pages : 618
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Book Description
Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Author: Márta Korbonits
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805584296
Category : Medical
Languages : en
Pages : 305
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Book Description
It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.
Author: Todd Leff
Publisher: John Wiley & Sons
ISBN: 9783527629534
Category : Science
Languages : en
Pages : 530
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Book Description
This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.
Author: Anthony H. Barnett
Publisher: John Wiley & Sons
ISBN: 0470011092
Category : Medical
Languages : en
Pages : 324
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Book Description
Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.
Author: Naveed Sattar
Publisher: John Wiley & Sons
ISBN: 1444312707
Category : Medical
Languages : en
Pages : 64
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Book Description
Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.
Author: Colleen Croniger
Publisher: BoD – Books on Demand
ISBN: 9533075988
Category : Medical
Languages : en
Pages : 386
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Book Description
Adipocytes are important in the body for maintaining proper energy balance by storing excess energy as triglycerides. However, efforts of the last decade have identified several molecules that are secreted from adipocytes, such as leptin, which are involved in signaling between tissues and organs. These adipokines are important in overall regulation of energy metabolism and can regulate body composition as well as glucose homeostasis. Excess lipid storage in tissues other than adipose can result in development of diabetes and nonalcoholic fatty liver disease (NAFLD). In this book we review the role of adipocytes in development of insulin resistance, type 2 diabetes and NAFLD. Because type 2 diabetes has been suggested to be a disease of inflammation we included several chapters on the mechanism of inflammation modulating organ injury. Finally, we conclude with a review on exercise and nutrient regulation for the treatment of type 2 diabetes and its co-morbidities.
Author: E. I. Sokolov
Publisher: VSP
ISBN: 9789067642125
Category : Medical
Languages : en
Pages : 338
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Book Description
This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient.
Author: Victor R. Preedy
Publisher: CRC Press
ISBN: 1439879885
Category : Medical
Languages : en
Pages : 456
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Book Description
Adipokines (also called adipocytokines) are a group of peptides secreted by adipose tissue. They have diverse roles, from functions in the individual cell to the whole body. This volume examines a wide range of specific adipokines as well as their general cellular aspects, including thermal stress and adipokine expression, central nervous system ro
