UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS

UPSTREAM AND DOWNSTREAM PROCESSING OF BIOPRODUCTS PDF Author: R. Puvanakrishnan
Publisher: MJP Publisher
ISBN:
Category : Technology & Engineering
Languages : en
Pages : 242

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Book Description
Microorganisms have been exploited for many centuries for the production of fermented foods and beverages and for bread-making. The production of alcoholic beverages using microbes was the first major industrialized process. The technology developed for large-scale brewing was adapted for other anaerobic processes such as acetone and butanol in the early 1900s. With the discovery of penicillins, rapid developments were made in the technology of submerged culture fermentation of aerobic microorganisms under controlled conditions. The advancements in microbiology and process biochemistry improved our ability to harness the potential of microorganisms through improved bioprocessing methods to manufacture new products with economic viability. Microbial derived bioproducts have been gaining importance in the food, pharmaceutical, textile, leather, cosmetic and chemical industries, and most important among them are therapeutic proteins and peptides, enzymes, antigens, vaccines, antibiotics, drugs, etc.Not all microbial production processes involve culture of the organism in liquid medium. Instead, the organism can be grown on the surface of a solid substrate. Solid substrate (or solid state) fermentation (SSF) is an established traditional technology in many countries, producing edible mushrooms, fungal- fermented foods and soy sauce. Before the development of processes in liquid culture, citric acid and some microbial enzymes were produced by SSF. Carbon composting is also a form of SSF.

Bioprocess Engineering

Bioprocess Engineering PDF Author: Pau Loke Show
Publisher: CRC Press
ISBN: 0429882521
Category : Medical
Languages : en
Pages : 233

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Book Description
Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Downstream Process Technology: A New Horizon In Biotechnology

Downstream Process Technology: A New Horizon In Biotechnology PDF Author: Krishna Kant Prasad
Publisher: PHI Learning Pvt. Ltd.
ISBN: 812034040X
Category : Mathematics
Languages : en
Pages : 374

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Book Description
Today, biochemical process industry demands fast and economic processes for the partitioning and purification of biomolecules that give high yield and high purity of the product. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification. The aim of this comprehensive text is to provide an insightful overview of the whole aspects of downstream processing for biochemical product recovery. Intended for undergraduate and postgraduate students of biotechnology and chemical engineering, this self-contained text includes the chapters based on the recent developments in the industry and academics. It covers the importance of the downstream processing in terms of its relevancy to modern days ever-changing consumer needs, process design criteria relevance to set objectives, and physicochemical factors that help to formulate the strategy to develop a configuration among the raw material, methodology and instruments. This overview is followed by different downstream processing steps. The text concludes with the discussion on stabilization of the product to improve the shelf life of the product. Key Features Includes detailed biological, mathematical, chemical and physical aspects of downstream processing. Distinguishes downstream processing from analytical bioseparation. Contains numerous illustrations and solved problems.

Bioprocess Engineering

Bioprocess Engineering PDF Author: Kim Gail Clarke
Publisher: Elsevier
ISBN: 1782421688
Category : Technology & Engineering
Languages : en
Pages : 266

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Book Description
Biotechnology is an expansive field incorporating expertise in both the life science and engineering disciplines. In biotechnology, the scientist is concerned with developing the most favourable biocatalysts, while the engineer is directed towards process performance, defining conditions and strategies that will maximize the production potential of the biocatalyst. Increasingly, the synergistic effect of the contributions of engineering and life sciences is recognised as key to the translation of new bioproducts from the laboratory bench to commercial bioprocess. Fundamental to the successful realization of the bioprocess is a need for process engineers and life scientists competent in evaluating biological systems from a cross-disciplinary viewpoint. Bioprocess engineering aims to generate core competencies through an understanding of the complementary biotechnology disciplines and their interdependence, and an appreciation of the challenges associated with the application of engineering principles in a life science context. Initial chapters focus on the microbiology, biochemistry and molecular biology that underpin biocatalyst potential for product accumulation. The following chapters develop kinetic and mass transfer principles that quantify optimum process performance and scale up. The text is wide in scope, relating to bioprocesses using bacterial, fungal and enzymic biocatalysts, batch, fed-batch and continuous strategies and free and immobilised configurations. - Details the application of chemical engineering principles for the development, design, operation and scale up of bioprocesses - Details the knowledge in microbiology, biochemistry and molecular biology relevant to bioprocess design, operation and scale up - Discusses the significance of these life sciences in defining optimum bioprocess performance

Advances in Feedstock Conversion Technologies for Alternative Fuels and Bioproducts

Advances in Feedstock Conversion Technologies for Alternative Fuels and Bioproducts PDF Author: Majid Hosseini
Publisher: Academic Press
ISBN: 0128179384
Category : Science
Languages : en
Pages : 416

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Book Description
Advances in Feedstock Conversion Technologies for Alternative Fuels and Bioproducts: New Technologies, Challenges and Opportunities highlights the novel applications of, and new methodologies for, the advancement of biological, biochemical, thermochemical and chemical conversion systems that are required for biofuels production. The book addresses the environmental impact of value added bio-products and agricultural modernization, along with the risk assessment of industrial scaling. The book also stresses the urgency in finding creative, efficient and sustainable solutions for environmentally conscious biofuels, while underlining pertinent technical, environmental, economic, regulatory and social issues. Users will find a basis for technology assessments, current research capability, progress, and advances, as well as the challenges associated with biofuels at an industrial scale, with insights towards forthcoming developments in the industry. - Presents a thorough overview of new discoveries in biofuels research and the inherent challenges associated with scale-up - Highlights the novel applications and advancements for biological, biochemical, thermochemical and chemical conversion systems that are required for biofuels production - Evaluates risk management concerns, addressing the environmental impact of value added bio-products and agricultural modernization, and the risk assessment of industrial scaling

Biomass and Biofuels from Microalgae

Biomass and Biofuels from Microalgae PDF Author: Navid R. Moheimani
Publisher: Springer
ISBN: 3319166409
Category : Technology & Engineering
Languages : en
Pages : 373

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Book Description
This comprehensive book details the most recent advances in the microalgae biological sciences and engineering technologies for biomass and biofuel production in order to meet the ongoing need for new and affordable sources of food, chemicals and energy for future generations. The chapters explore new microalgae cultivation techniques, including solid (biofilm) systems, and heterotrophic production methods, while also critically investigating topics such as combining wastewater as a source of nutrients, the effect of CO2 on growth, and converting biomass to methane through anaerobic digestion. The book highlights innovative bioproduct optimization and molecular genetic techniques, applications of genomics and metabolomics, and the genetic engineering of microalgae strains targeting biocrude production. The latest developments in microalgae harvesting and dewatering technologies, which combine biomass production with electricity generation, are presented, along with detailed techno-economic modeling. This extensive volume was written by respected experts in their fields and is intended for a wide audience of researchers and engineers.

Putting Biotechnology to Work

Putting Biotechnology to Work PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309047854
Category : Science
Languages : en
Pages : 133

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Book Description
The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.

Bioseparations Science and Engineering

Bioseparations Science and Engineering PDF Author: Roger G. Harrison
Publisher: Oxford University Press
ISBN: 0190213736
Category : Technology & Engineering
Languages : en
Pages : 577

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Book Description
Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.

Development of Sustainable Bioprocesses

Development of Sustainable Bioprocesses PDF Author: Elmar Heinzle
Publisher: John Wiley & Sons
ISBN: 9780470058909
Category : Technology & Engineering
Languages : en
Pages : 316

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Book Description
Bioprocess technology involves the combination of living matter (whole organism or enzymes ) with nutrients under laboratory conditions to make a desired product within the pharmaceutical, food, cosmetics, biotechnology, fine chemicals and bulk chemicals sectors. Industry is under increasing pressure to develop new processes that are both environmentally friendly and cost-effective, and this can be achieved by taking a fresh look at process development; - namely by combining modern process modeling techniques with sustainability assessment methods. Development of Sustainable Bioprocesses: Modeling and Assessment describes methodologies and supporting case studies for the evolution and implementation of sustainable bioprocesses. Practical and industry-focused, the book begins with an introduction to the bioprocess industries and development procedures. Bioprocesses and bioproducts are then introduced, together with a description of the unit operations involved. Modeling procedures, a key feature of the book, are covered in chapter 3 prior to an overview of the key sustainability assessment methods in use (environmental, economic and societal). The second part of the book is devoted to case studies, which cover the development of bioprocesses in the pharmaceutical, food, fine chemicals, cosmetics and bulk chemicals industries. Some selected case studies include: citric acid, biopolymers, antibiotics, biopharmaceuticals. Supplementary material provides hands-on materials so that the techniques can be put into practice. These materials include a demo version of SuperPro Designer software (used in process engineering) and models of all featured case studies, excel sheets of assessment methods, Monte Carlo simulations and exercises. Previously available on CD-ROM, the supplementary material can now be accessed via http://booksupport.wiley.com by entering the author name, book title or isbn and clicking on the desired entry. This will then give a listing of all the content available for download. Please read any text files before downloading material.

Biobased Industrial Products

Biobased Industrial Products PDF Author: Committee on Biobased Industrial Products
Publisher: National Academies Press
ISBN: 0309521858
Category : Technology & Engineering
Languages : en
Pages : 163

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Book Description
Petroleum-based industrial products have gradually replaced products derived from biological materials. However, biologically based products are making a comeback--because of a threefold increase in farm productivity and new technologies. Biobased Industrial Products envisions a biobased industrial future, where starch will be used to make biopolymers and vegetable oils will become a routine component in lubricants and detergents. Biobased Industrial Products overviews the U.S. land resources available for agricultural production, summarizes plant materials currently produced, and describes prospects for increasing varieties and yields. The committee discusses the concept of the biorefinery and outlines proven and potential thermal, mechanical, and chemical technologies for conversion of natural resources to industrial applications. The committee also illustrates the developmental dynamics of biobased products through existing examples, as well as products still on the drawing board, and it identifies priorities for research and development.