Unusual Cases in Peritoneal Surface Malignancies PDF Download
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Author: Emel Canbay
Publisher: Springer
ISBN: 3319515233
Category : Medical
Languages : en
Pages : 144
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Book Description
This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies which have originated from different primaries, such as breast cancer, small bowel cancers and imatinib resistant GISTosis and sarcomas and pseudomyxoma. The book provides the most up-to-date information on current approaches such as cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Given the increasing evidence that the patients who may benefit from this treatment modality avoid potential lethal course of these diseases, the book explores the application of these approaches to a number of types of malignancy. The first chapters explore Benign Multicystic Mesothelioma and Pseudomyxoma Peritonei arising from unusual primaries. Among other explored topics are peritoneal metastases from serous papillary uterine carcinoma, sarcoma and from unusual origins. This book is valuable for surgical oncologists who deal with the management of peritoneal surface malignancies.
Author: Emel Canbay
Publisher: Springer
ISBN: 3319515233
Category : Medical
Languages : en
Pages : 144
Get Book Here
Book Description
This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies which have originated from different primaries, such as breast cancer, small bowel cancers and imatinib resistant GISTosis and sarcomas and pseudomyxoma. The book provides the most up-to-date information on current approaches such as cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Given the increasing evidence that the patients who may benefit from this treatment modality avoid potential lethal course of these diseases, the book explores the application of these approaches to a number of types of malignancy. The first chapters explore Benign Multicystic Mesothelioma and Pseudomyxoma Peritonei arising from unusual primaries. Among other explored topics are peritoneal metastases from serous papillary uterine carcinoma, sarcoma and from unusual origins. This book is valuable for surgical oncologists who deal with the management of peritoneal surface malignancies.
Author: Angelo Di Giorgio
Publisher: Springer
ISBN: 8847057116
Category : Medical
Languages : en
Pages : 398
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Book Description
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.
Author: U. Metzger
Publisher: Springer Science & Business Media
ISBN: 3642824323
Category : Medical
Languages : en
Pages : 170
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Book Description
One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Author: Emel Canbay
Publisher:
ISBN: 9783319129389
Category : Colon (Anatomy)
Languages : en
Pages : 109
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Book Description
This book describes the comprehensive management and treatment of peritoneal surface malignancies. The authors look at new intraperitoneal drugs, laparoscopic approaches for cytoreductive surgery, intraperitoneal chemotherapy applications as well as new surgical techniques to guide the readers in curing patients with peritoneal metastases. The use of biomolecular markers and morphological examination scoring systems described in this book help predict the extent of the diseases to aid in the diagnosis and treatment of patients. Peritoneal Surface Malignancies- A Curative Approach is an easy-to-follow book on the management and treatment of peritoneal metastases, aimed at surgeons, oncologists and trainees in their daily clinical practice and surgical preparations.
Author: Paul H. Sugarbaker
Publisher: Springer Science & Business Media
ISBN: 1461312477
Category : Medical
Languages : en
Pages : 434
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Book Description
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 194
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Book Description
Author: Aditi Bhatt
Publisher: Springer
ISBN: 9811070539
Category : Medical
Languages : en
Pages : 577
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Book Description
The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.
Author: wim ceelen
Publisher: Springer Science & Business Media
ISBN: 0387489932
Category : Medical
Languages : en
Pages : 548
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Book Description
This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Illustrations aid the reader throughout in the many facets of this disease. The book will be of particular interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC.
Author: F. Kristian Storm
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 600
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Book Description
Author: Olivier Glehen
Publisher: Springer Nature
ISBN: 9811537739
Category : Medical
Languages : en
Pages : 281
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Book Description
This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors.
