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Author: Gianni Marone
Publisher: Academic Press
ISBN: 0080535852
Category : Medical
Languages : en
Pages : 738
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Book Description
Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.
Author: Gianni Marone
Publisher: Academic Press
ISBN: 0080535852
Category : Medical
Languages : en
Pages : 738
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Book Description
Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.
Author: Alasdair M. Gilfillan
Publisher: Springer Science & Business Media
ISBN: 1441995331
Category : Medical
Languages : en
Pages : 312
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Book Description
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Author: Bernhard F. Gibbs
Publisher: Springer Nature
ISBN: 1071606964
Category : Medical
Languages : en
Pages : 379
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Book Description
This second edition provides updated and new chapters to build on and extend the strengths of the first edition. Chapters guide readers through basic biology of basophils, obtaining the cells by purification, culture of stem cells progenitors, peripheral CD34+ stem cell-derived mast cells, basophils from CD34+ progenitors, diagnostic applications, gene expression patterns in basophils, roles of basophils in different asthma phenotypes, knockout, and disease models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Basophils and Mast Cells: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.
Author: Ann M. Dvorak
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805578644
Category : Medical
Languages : en
Pages : 377
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Book Description
In this book, the author reviews the ultrastructural studies of basophils and mast cells performed since the publication of an earlier monograph in 1991. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. Including more than 180 excellent micrographs, this book will be of interest to basic scientists in immunology, cell biology, secretion and angiogenesis research, and histochemistry. As mast cells and basophils play a crucial role in various diseases, it will be essential reading for allergists, immunologists, dermatologists, hematologists, gastroenterologists, rheumatologists, neurologists, pathologists, pulmonologists, and cardiologists.
Author: Ehud Razin
Publisher: Springer Science & Business Media
ISBN: 9780387986258
Category : Gardening
Languages : en
Pages : 454
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Book Description
Mast cells and basophils are responsible for inflammatory and allergic reactions. As such, the signals that generate these responses and how their pathways of action work are the focus of much present day research into allergy and inflammation. This book focuses primarily on the molecular mechanisms that govern mast cell and basophil cell biology and function, as well as providing a comprehensive summary of the field of signal transduction and also giving insights into areas that have therapeutic potential. The book provides detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide the reader with an up-to-date account of a topic where the rapid progress makes conventional information gathering difficult.
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Guha Krishnaswamy
Publisher: Springer Science & Business Media
ISBN: 1592599672
Category : Medical
Languages : en
Pages : 434
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Book Description
A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.
Author: Kazuwa Nakao
Publisher: Springer
ISBN: 4431556516
Category : Science
Languages : en
Pages : 330
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Book Description
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004
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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309048311
Category : Science
Languages : en
Pages : 321
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Book Description
More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and schoolâ€"where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.
