The Winding Road to Discovering IPS Cells PDF Download
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Author: Shin'ya Yamanaka
Publisher:
ISBN: 9784866581774
Category : Biologists
Languages : en
Pages : 155
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Book Description
"The revolutionary discovery of induced pluripotent stem cells, or iPS cells, completely changed the world, particularly in the field of medical science. This groundbreaking achievement was made by Dr. Yamanaka Shinya of Kyoto University and won him the Nobel Prize for Physiology or Medicine in 2012. The road that led him to this accomplishment, however, was not an easy one; during his early days as a training orthopedic surgeon, Yamanaka was not skilled and was called "a hindrance" by his supervisor. He eventually changed course to become a researcher in the field of medical science and undertook postdoctoral studies in the United States, but he experienced a mild case of depression upon returning to Japan. Even when Yamanaka presented the results of his discovery of iPS cells, he could not immediately bask in the glory of his success, since many of his peers simply could not believe his achievement. In this volume, the Nobel Prize laureate talks openly about his life from his childhood days to his current daily life and discusses his views on the future of regenerative medicine. How were iPS cells developed and what can they do? Translated from a runaway bestseller in Japan and replete with a new preface for the English edition, this biography shows what science can do for mankind, and the possibilities that life holds." --back cover.
Author: Shin'ya Yamanaka
Publisher:
ISBN: 9784866581774
Category : Biologists
Languages : en
Pages : 155
Get Book Here
Book Description
"The revolutionary discovery of induced pluripotent stem cells, or iPS cells, completely changed the world, particularly in the field of medical science. This groundbreaking achievement was made by Dr. Yamanaka Shinya of Kyoto University and won him the Nobel Prize for Physiology or Medicine in 2012. The road that led him to this accomplishment, however, was not an easy one; during his early days as a training orthopedic surgeon, Yamanaka was not skilled and was called "a hindrance" by his supervisor. He eventually changed course to become a researcher in the field of medical science and undertook postdoctoral studies in the United States, but he experienced a mild case of depression upon returning to Japan. Even when Yamanaka presented the results of his discovery of iPS cells, he could not immediately bask in the glory of his success, since many of his peers simply could not believe his achievement. In this volume, the Nobel Prize laureate talks openly about his life from his childhood days to his current daily life and discusses his views on the future of regenerative medicine. How were iPS cells developed and what can they do? Translated from a runaway bestseller in Japan and replete with a new preface for the English edition, this biography shows what science can do for mankind, and the possibilities that life holds." --back cover.
Author: Michael Fuller
Publisher: Springer Nature
ISBN: 3031062779
Category : Social Science
Languages : en
Pages : 226
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Book Description
This book brings together selected papers from scientists, theologians and philosophers who took part in the 2021 conference of the European Society for the Study of Science and Theology based in Madrid, Spain. The contributions constitute a cutting-edge resource for considering questions from interdisciplinary perspectives, covering both the crucial role played by images and models in our thinking and also the limitations which are inherent in these linguistic devices. Questions addressed include: Can this use of images and models generate a creative pluralism, enabling us to think outside the disciplinary silos which are a feature of academic discourse? Can they enable fruitful, synergistic, interdisciplinary conversations? This book will appeal to students and academics alike, particularly those working in the fields of philosophy, theology, ethics and the history of science.
Author: Miquéias Lopes-Pacheco
Publisher: Frontiers Media SA
ISBN: 2889633675
Category :
Languages : en
Pages : 281
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Book Description
Author: K. Natwar-Singh
Publisher: Conran Octopus
ISBN: 9788129132741
Category : Biography & Autobiography
Languages : en
Pages : 0
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Book Description
The book is an autobiography of the former External Affairs Minister and senior Congress Party leader Natwar Singh. In the autobiography, Natwar Singh has shared his experiences on several events in the political corridors of Delhi. He has also described his early years as a diplomat, his proximity to former Prime Ministers Indira Gandhi and Rajiv Gandhi and to events post-Rajiv Gandhi's assassination in 1991 - including information about Sonia Gandhi, the President of the Congress Party.
Author: Linda Bogar
Publisher: Springer
ISBN: 9783319580531
Category : Medical
Languages : en
Pages : 0
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Book Description
This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
Author: Raul Delgado-Morales
Publisher: Springer
ISBN: 9783030080761
Category : Science
Languages : en
Pages : 0
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Book Description
This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer’s disease, cancer, and heart disorders, the book summarizes the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.
Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 336
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Book Description
Author: Rhian M. Touyz
Publisher: Springer
ISBN: 3030164810
Category : Medical
Languages : en
Pages : 497
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Book Description
This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Author: Robert McLeish
Publisher: CRC Press
ISBN: 1317590945
Category : Technology & Engineering
Languages : en
Pages : 435
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Book Description
Radio Production is for professionals and students interested in understanding the radio industry in today’s ever-changing world. This book features up-to-date coverage of the purpose and use of radio with detailed coverage of current production techniques in the studio and on location. In addition there is exploration of technological advances, including handheld digital recording devices, the use of digital, analogue and virtual mixing desks and current methods of music storage and playback. Within a global context, the sixth edition also explores American radio by providing an overview of the rules, regulations, and purpose of the Federal Communications Commission. The sixth edition includes: Updated material on new digital recording methods, and the development of outside broadcast techniques, including Smartphone use. The use of social media as news sources, and an expansion of the station’s presence. Global government regulation and journalistic codes of practice. Comprehensive advice on interviewing, phone-ins, news, radio drama, music, and scheduling. This edition is further enhanced by a companion website, featuring examples, exercises, and resources: www.focalpress.com/cw/mcleish.
Author: Goran K Hansson
Publisher: World Scientific
ISBN: 9814651478
Category : Medical
Languages : en
Pages : 406
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Book Description
Physiology or medicine was the third prize area Alfred Nobel mentioned in his will. Nobel had an active interest in medical research. He came into contact with Swedish physiologist Jöns Johansson through Karolinska Institute around 1890. Johansson worked for a brief period in Nobel's laboratory in Sevran, France during the same year. The Nobel Prize in Physiology or Medicine is awarded by the Nobel Assembly at Karolinska Institute. This volume is a collection of the Nobel lectures delivered by the Nobel Laureates, together with their biographies and the presentation speeches for the period 2006-2010.List of Laureates and their award citations:(2006) Andrew Z Fire and Craig C Mello — for their discovery of RNA interference-gene silencing by double-stranded RNA;(2007) Mario R Capecchi, Martin J Evans and Oliver Smithies — for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells;(2008) Harald zur Hausen — for his discovery of human papilloma viruses causing cervical cancer, and Françoise Barré-Sinoussi and Luc Montagnier — for their discovery of human immunodeficiency virus;(2009) Elizabeth H Blackburn, Carol W Greider and Jack W Szostak — for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase;(2010) Robert G Edwards — for the development of in vitro fertilization.
