The Sigma-RBI Handbook of Receptor Classification and Signal Transduction PDF Download
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Author: Keith J. Watling
Publisher:
ISBN: 9780964054844
Category : Carrier proteins
Languages : en
Pages : 376
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Book Description
Author: Keith J. Watling
Publisher:
ISBN: 9780964054844
Category : Carrier proteins
Languages : en
Pages : 376
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Book Description
Author: Hans Vogel
Publisher: Springer Science & Business Media
ISBN: 3540714200
Category : Medical
Languages : en
Pages : 2118
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Book Description
The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
Author: William D. Willis Jr.
Publisher: Springer Science & Business Media
ISBN: 1461500354
Category : Medical
Languages : en
Pages : 1016
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Book Description
The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neu rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy of these neurons in Chapter 4. The description of the dorsal horn in the previous Chapter 4 is now included in Chapter 5, and the chemical neuroanatomy of the dorsal horn in Chapter 6. Furthermore, discussions of the descending control systems have now been consolidated at the end of Chapter 12. The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations.
Author: Mark Schena
Publisher: Jones & Bartlett Learning
ISBN: 9780763731274
Category : Protein microarrays
Languages : en
Pages : 510
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Book Description
Protein Microarrays is one of the first books in this exciting new technology and will be an essential reference for most biologists and biotechnology professionals.
Author: Leslie Iversen
Publisher: Oxford University Press
ISBN: 0195380533
Category : Medical
Languages : en
Pages : 568
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Book Description
The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
Author: Joseph G. Cannon
Publisher: American Chemical Society
ISBN: 0841239274
Category : Language Arts & Disciplines
Languages : en
Pages : 335
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Book Description
The book is intended for chemists entering medicinal chemistry research who have no knowledge of pharmacology. Pharmacological principles and concepts are emphasized, rather than a survey of large numbers of specific drugs. It is intended to serve as a tool to prepare the reader for further in-depth study in many areas of pharmacology.
Author: Joseph Besharse
Publisher: Academic Press
ISBN: 012374203X
Category : Science
Languages : en
Pages : 2352
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Book Description
As the first comprehensive reference for the eye, its support structures, diseases, and treatments, Encyclopedia of the Eye is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues. This Encyclopedia is invaluable for graduate students and postdoctoral fellows who are seeking an introduction to an area of eye research. Each chapter explains the basic concepts and provides references to relevant chapters within the Encyclopedia and more detailed articles across the wider research literature. The Encyclopedia is also particularly useful for visual scientists and practitioners who are researching a new area, seeking deeper understanding of important research articles in fields adjacent to their own, or reviewing a grant outside their immediate area of expertise. Written by experts at a level that permits students to grasp key elements of a specific subject Provides an entryway into the major features of current eye research No other source puts this much information, so well-indexed and with so many helpful full color figures and graphics, in the hands of the ophthalmic scientist
Author: Susan Miller
Publisher: Elsevier
ISBN: 0128243058
Category : Medical
Languages : en
Pages : 684
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Book Description
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Author: Jack R. Cooper
Publisher: Oxford University Press, USA
ISBN: 0195140079
Category : Medical
Languages : en
Pages : 417
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Book Description
Aside from the usual updating of material, the major change in this edition is an extensive rewriting of the chapter on memory and learning to emphasize that genes that are involved in behavior are not immutable but their expression can be modified by transcription factors. Thus, with respect to learning, that old question about which is more important, nature or nuture, genetics or environment, should be answered with the question, which leg is more important for walking, the left or the right?
Author: Miles Hacker
Publisher: Academic Press
ISBN: 9780080919225
Category : Medical
Languages : en
Pages : 608
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Book Description
Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. Uses individual drugs to explain molecular actions Full color art program explains molecular and chemical concepts graphically Logical structure reflecting the current state of pharmacology and translational research Covers such intricacies as drug resistance and cell death Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool
