The Organization of the Projection from the Cerebellar Cortex to the Nucleus Interpositus of the Cerebellum of the Cat PDF Download
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Author: Georgia Ann Bishop
Publisher:
ISBN:
Category : Cats
Languages : en
Pages : 264
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Book Description
Author: Georgia Ann Bishop
Publisher:
ISBN:
Category : Cats
Languages : en
Pages : 264
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Book Description
Author: B. Brown Gould
Publisher: Springer Science & Business Media
ISBN: 3642676146
Category : Medical
Languages : en
Pages : 149
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Book Description
The afferent connections of the cerebellar cortex of the cat have been extensively in vestigated by Alf Brodal and his collaborators using retrograde degeneration methods. These experiments (reviewed in Larsell and Jansen 1972) established that cerebellar corti cal afferents arise from widespread areas of the brain stem and spinal cord. Brain stem nuclei shown to provide input to the cerebellar cortex included the pontine nuclei, the medial and descending vestibular nuclei, vestibular cell group x, the lateral reticular nucleus, the perihypoglossal nuclei, the paramedian reticular nucleus, the inferior olive, and the external cuneate nucleus. In addition, the red nucleus and certain of the raphe nuclei were thought to send fibers to the intracerebellar nuclei, but not to the cortex. With the advent of the horseradish peroxidase (HRP) technique, new information on the distribution and organization of cerebellar cortical afferents has recently be come available. Thus Gould and Graybiel (1976) demonstrated that afferents to the cat cerebellar cortex arise from a previously undescribed lateral tegmental cell group at the level of the isthmus and from the intracerebellar nuclei, as well as from the classic precerebellar nuclei. Moreover, these studies showed that fibers from the vestibular nuclei, previously thought to be distributed only to the flocculonodular lobe and uvula, reach widespread areas of the cerebellar cortex. Experiments by other investi gators have established that the cerebellar cortex of the cat receives afferents from cer tain of the raphe nuclei (Shinnar et al. 1975; Taber Pierce et al.
Author: B. Brown Gould
Publisher:
ISBN: 9783642676154
Category :
Languages : en
Pages : 104
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Book Description
Author: George Paxinos
Publisher: Academic Press
ISBN: 008092137X
Category : Science
Languages : en
Pages : 1053
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Book Description
The previous editions of The Rat Nervous System were indispensable guides for those working on the rat and mouse as experimental models. The fourth edition enhances this tradition, providing the latest information in the very active field of research on the brain, spinal cord, and peripheral nervous system. The structure, connections, and function are explained in exquisite detail, making this an essential book for any graduate student or scientist working on the rat or mouse nervous system. - Completely revised and updated content throughout, with entirely new chapters added - Beautifully illustrated so that even difficult concepts are rendered comprehensible - Provides a fundamental analysis of the anatomy of all areas of the central and peripheral nervous systems, as well as an introduction to their functions - Appeals to researchers working on other species, including humans
Author: Mario Manto
Publisher: Springer
ISBN: 9789400713321
Category : Medical
Languages : en
Pages : 0
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Book Description
Our knowledge of cerebellar functions and cerebellar disorders, called ataxias, is increasing considerably. Studies of the cerebellum are now a central focus in neuroscience. During the last four decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and biology of mental processes, behavioral symptoms, and emotion. It is now accepted that the cerebellum acts as a cognitive operator in learning, perception, and attention. Moreover, major improvements in our assessment of in vivo cerebellar architecture using imaging techniques have occurred. A typical example is the accurate description of cerebellar anatomy during fetal development with MRI, a progress which has direct impacts on patient care. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias. More than 20 new genes have been identified these last 10 years. Only for dominant ataxias, more than 30 diseases have now been unravelled. The number of ataxic disorders will increase with aging, the cerebellum being the structure of the brain with the most important loss of neurons with age. More than 300 different cerebellar disorders are encountered during daily practice, but we are missing a single source of information explaining their pathogenesis. Despite the immense amount of knowledge acquired about the cerebellar circuitry these last years, a large book covering the neuroscience of the cerebellum is missing. The goal of this endeavour is to bring up to date information relevant for basic science and also for clinical activities. To reach this goal, the most renowned authors are gathered in a unique and in-depth book with a format of a handbook. We emphasize the connections between molecular findings, imaging features, behavioural/neuropsychological aspects, and clinical implications.
Author: Andreas Plaitakis
Publisher: Springer Science & Business Media
ISBN: 1461535107
Category : Medical
Languages : en
Pages : 507
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Book Description
This book encompasses basic and clinical reports on the cerebellum and its primary atrophic disorders, the cerebellar degenerations. Rapid progress has been made in undestanding the organization and function of the cerebellum at the neuronal, synaptic, and molecular level. Of particular importance has been the identification of the chemical transmitters utilized by the cer ebellar cellular systems. More than any other brain region, the cerebellum utilizes amino acids as its main excitatory and inhibitory neurotransmitters. Excitatory amino acid transmitters, in addition to serving neuronal com munication, may also mediate trophic and toxic effects, and as such, they may playa role in neurodegenerative processes. The cerebellar degenerations were among the first human disorders with primary system atrophy to be studied clinically and pathologically. This field of clinical cerebellar sciences, no longer confined to the previously known descriptive level, is now advancing rapidly, propelled by rapid advances in neuroimaging, immunology, and molecular biology. The advent of CT, MRI, and PET has in recent years permitted the study of central nervous system alterations in living patients, thus contributing substantially to the accuracy of the diagnosis and the classification of these disorders. The nosology of cerebellar degenerations, which has been the subject of much debate for over a century, is presently a dynamic field, with new entities being recognized and old "classic ataxias" being redefined in the light of new genetic evidence.
Author: Masao Itō
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 608
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Book Description
Author: Joseph Altman
Publisher: CRC Press
ISBN:
Category : Medical
Languages : en
Pages : 824
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Book Description
This book is an outstanding presentation of what happens during normal cerebellar development.
Author: V. Chan-Palay
Publisher: Springer
ISBN: 3642664989
Category : Medical
Languages : en
Pages : 569
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Book Description
Recent physiologic investigations have shown that the deep cerebellar nuclei may play an important role in the initiation and monitoring of skilled move ments. Much of this physiologic work has been carried out in the absence of a secure foundation in neuroanatomical information. Although the main sources of the afferent fibers and the major terminations of the efferent fibers related to these nuclei have been known for many years, remarkably little information about the organization of the nuclei themselves has been collected. The kinds of nerve cells, their arrangement within the nuclei, the patterns of their dendritic arborizations, the distribution of incoming fibers among the neurons, the relationship between the outgoing nerve fibers and the nerve cells from which they originate - these and many other morphologic features were either unknown or only superficially explored. In fact, so little was known about the deep cerebellar nuclei when I began to work on this subject that the investigations reported here are virtually without antecedents, a refreshing change from the cerebellar cortex which has been repeatedly and exhaustively surveyed. My studies on the cerebellar nuclei began in the spring of 1972. They were initiated with the intent of applying the principles of analysis that had been developed for the cerebellar cortex to a different but related part of the brain.
Author: Egidio D'Angelo
Publisher: Frontiers E-books
ISBN: 2889190757
Category :
Languages : en
Pages : 133
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Book Description
This Research Topic is centered around the attempt to understand network activity of the brain by combining experimental and modeling techniques. A surprisingly rich set of new observations is emerging about the functions of the olivo-cerebellar cortical modules. This Research Topic will consider the critical elements of new emerging knowledge achieved using in vitro and in vivo techniques and the computational attempts at functional circuit reconstruction.
