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Author: Dr. Euan Angus Ashley
Publisher: Celadon Books
ISBN: 1250234972
Category : Science
Languages : en
Pages : 221
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Book Description
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.
Author: Dr. Euan Angus Ashley
Publisher: Celadon Books
ISBN: 1250234972
Category : Science
Languages : en
Pages : 221
Get Book Here
Book Description
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.
Author: EUAN ANGUS. ASHLEY
Publisher:
ISBN: 1250234980
Category : Business & Economics
Languages : en
Pages : 0
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Book Description
The future of medicine is already here. Dr. Euan Ashley, Stanford professor of medicine and genetics, leads the charge with his contributions to the practice of precision medicine, a concept that has already sparked massive improvements in the way doctors diagnose, treat, and prevent disease, and will continue to make a meaningful difference for anyone dealing with serious illness. In The Genome Odyssey, Dr. Ashley brings to vivid life the advancements his team has made in the field of genetic medicine. He shares the real diagnostic journeys of patients as their incredibly rare diseases are identified and effective treatment plans determined. The secret to Dr. Ashley’s breakthroughs? His team was the first to successfully analyze a complete human genome. In fact, they hold the world record for the fastest genome sequencing at five hours and two minutes. With this capability to analyze their patients’ full genetic makeup, Dr. Ashley’s team is able to predict a patient’s genetic future and to diagnose and, in some cases, prevent disease before it even begins. The Genome Odyssey unfolds like a thrilling medical mystery and points us towards a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized. Destined to become a classic work of modern science, The Genome Odyssey illustrates the groundbreaking hunt to prevent, predict, and possibly even defeat disease.
Author: Spencer Wells
Publisher: Princeton University Press
ISBN: 0691176019
Category : Reference
Languages : en
Pages : 238
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Book Description
Around 60,000 years ago, a man, genetically identical to us, lived in Africa. Every person alive today is descended from him. How did this real-life Adam wind up as the father of us all? What happened to the descendants of other men who lived at the same time? And why, if modern humans share a single prehistoric ancestor, do we come in so many sizes, shapes, and races? Examining the hidden secrets of human evolution in our genetic code, the author reveals how developments in the revolutionary science of population genetics have made it possible to create a family tree for the whole of humanity. Replete with marvelous anecdotes and remarkable information, from the truth about the real Adam and Eve to the way differing racial types emerged, this book is an enthralling, epic tour through the history and development of early humankind.
Author: Elizabeth Finkel
Publisher: Melbourne Univ. Publishing
ISBN: 0522856470
Category : Science
Languages : en
Pages : 290
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Book Description
The year 2001 marked more than just the beginning of Stanley Kubrick's Space Odyssey, it marked the beginning of the genome era. That was the year scientists first read the 3 billion letters of DNA that make up the human genome. This was followed by a veritable Noah's Ark of genomesandmdash;sponges and worms, dogs and cows, rice and wheat, chimps and elephantsandmdash;180 creatures aboard so far. So what have we learned from all this? How has it changed the way we practise medicine, grow crops and breed livestock? What have we learned about evolution? These are the questions science writer and molecular biologist Elizabeth Finkel asked herself four years ago. To find the answers she travelled the science frontier from Botswana to Boston, from Warracknabeal to Mexico and tracked down scientists working in the field. Their stories, told here, paint the picture of what it means to be part of the genome generation. 'The Genome Generation is absolutely riveting. These tales from the frontier are a 'must read' for everyone who wishes to understand our pastandmdash;the logic of evolutionandmdash;or take a peep into our exciting future at the creation of 'super plants' through 'digital agriculture'.'andmdash;R.A. Mashelkar, CSIR Bhatnagar Fellow and India President, Global Research Alliance
Author: Thomas Armstrong, PhD
Publisher: Courier Dover Publications
ISBN: 0486831809
Category : Psychology
Languages : en
Pages : 371
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Book Description
"This is truly a major contribution — brilliant, beguiling, and as broad in concept as it is deep." — Jean Houston, PhD, author of The Possible Human Thomas Armstrong, Ph.D., an award-winning educator and expert on human development, offers a cross-cultural view of life's entire journey, from before birth to death to the possibilities of an afterlife. Dr. Armstrong cites both clinical research and anecdotal evidence in a comprehensive view of the challenges and opportunities we face at every stage of our development. His accessible narrative incorporates elements of history, literature, psychology, spirituality, and science in a fascinating guide to understanding our past as well as our future. "I loved the tone, the pacing, the sense of audience, and especially the richness of the associations . . . It's a book that one would like to keep around — a guidebook even." — John Kotre Ph.D., co-author of Seasons of Life: The Dramatic Journey from Birth to Death "The Human Odyssey is superb, magnificent, astonishing, unique, engrossing, eminently readable, informative, enjoyable, entertaining, profound. What else? I could go on. I hadn't expected anything like so remarkable a book." — Joseph Chilton Pearce, author of The Crack in the Cosmic Egg and Magical Child "I have read through The Human Odyssey. It is in many ways impressive. I also think that it has great commercial potential. Many people will find attractive your dual focus on the scientific and the soul/spiritual dimensions." — Howard Gardner, Ph.D., The John H. and Elizabeth A. Hobbs Professor in Cognition and Education at the Harvard Graduate School of Education, author of Frames of Mind "I extend my congratulations to you for this monumental undertaking and wish you the very best for your impressive efforts." — Marian Diamond, Ph.D. Professor, Department of Integrative Biology, University of California, Berkeley; co-author of Magic Trees of the Mind; pioneer researcher into the effect of the environment on brain development; dissected Einstein's brain "I very much enjoyed The Human Odyssey. Your breadth of sources is remarkable, and you have put them all together in a smooth and integrative way. I think it will be informative for people, and also inspiring for them to make their stages of life more meaningful. Overall, this is an impressive tour de force." — Arthur Hastings, Ph.D., Professor and Director, William James Center for Consciousness Studies, Institute of Transpersonal Psychology; Past President, Association of Transpersonal Psychology "Extraordinary. I hope that it is read by many people." — Laura Huxley, widow of Aldous Huxley, founder of Children: Our Ultimate Investment, and author of This Timeless Moment, and The Child of Your Dreams "A wonderful and encyclopedic summary of human development." — Allan B. Chinen, M.D., Clinical Professor of Psychiatry, University of California, San Francisco; author of Once Upon a Mid-Life: Classic Stories and Mythic Tales to Illuminate the Middle Years and In the Ever After: Fairy Tales and the Second Half of Life "Absolutely remarkable. The Human Odyssey is written with lively scholarship and contains great depth and breadth, a wide range of fascinating materials, and many useful resources. It's a kind of 'everything book.'" — George Leonard, "the granddaddy of the consciousness movement" (Newsweek) and author of The Transformation and The Ultimate Athlete "The Human Odyssey provides readers with a fresh approach to developmental psychology. Dr. Armstrong has included a spiritual dimension of human growth that is lacking from most accounts but which is essential for a complete understanding of the human condition. It is a splendid, brilliant work." — Stanley Krippner, Ph.D., former president of the Association for Humanistic Psychology, author of Personal Mythology: The Psychology of Your Evolving Self, and co-editor of The Psychological Impact of War Trauma on Civilians: An International Perspective "An integral approach to human development, from birth to death, that provides practical information for all who see spirit interpenetrating all of life." — Michael Murphy, co-founder of the Esalen Institute and author of The Future of the Body, The Life We Are Given, and God and the Evolving Universe "This is a thoroughly researched and beautifully written account of the story of human development. Drawing on the most recent scientific studies, as well as literature and films, mythology and major spiritual traditions, Armstrong shows the way to a truly integrated understanding of the complexities of the human life cycle." — Ralph Metzner, Ph.D., author of Maps of Consciousness and The Unfolding Self, co-author (with Timothy Leary and Richard Alpert) of The Psychedelic Experience, which was the inspiration for the Beatles' song "Tomorrow Never Knows" "I loved this book. What a vast terrain it covers! I enjoyed the way it wove into each developmental stage a rich array of materials from Greek myths, Martin Buber, psychology, rituals, spirituality, and so many wonderful stories. As people read this book, they will be much more aware of the different stages of life and how they impact all of us personally and collectively." — Barbara Findeisen, President, The Association for Pre- & Perinatal Psychology and Health and creator of the documentary film, The Journey to Be Born, featured on Oprah - "I'm awestruck! This looks like the most important book of the century." — Jan Hunt, author of The Natural Child: Parenting from the Heart; member of the board of directors of the Canadian Society for the Prevention of Cruelty to Children "The Human Odyssey is just that: a tour de force by one of the leading experts in whole person development. I've never before seen such a comprehensive and readable work on the many stages that we humans go through on our journey through this life." — John W. Travis, M.D., founder of the first wellness center in the United States in 1975, co-author of Wellness Workbook, and co-founder of Alliance for Transforming the Lives of Children. - "Thomas Armstrong's The Human Odyssey is an extraordinary book; an intellectual feast. Armstrong has amassed and integrated an amazing amount of information from developmental and transpersonal psychology, modern consciousness research, biology, anthropology, mythology, and art, and created an extraordinary guide through all the stages of the adventure of human life. While the rich content of this book will impress professional audiences, it's clear and easy style makes it quite accessible to the general public." — Stanislav Grof, M.D., former Chief of Psychiatric Research, Maryland Psychiatric Research Center; author of Realms of the Human Unconscious, Beyond the Brain: Birth, Death, and Transcendence in Psychotherapy and Adventures in Self-Discovery "Thomas Armstrong has written a brilliant, caring and beautiful book on the human lifecycle. Such an all-inclusive book is rare and adds a sense of the wholeness of life, into and beyond death, in the mere reading of it." — Stuart Sovatsky, Ph.D., author of Words From the Soul, Your Perfect Lips and Eros, Consciousness and Kundalini, and co-President of the Association of Transpersonal Psychology. "I cannot imagine anyone who will not benefit from this wise, beautifully written description of life's journey. If you are looking for encouragement, understanding, and strength, this is your book." — Larry Dossey, M.D., author of The Extraordinary Power of Ordinary Things and Healing Words "A beautiful compilation of world wisdom. Well written and inspiring." — James Fadiman, Ph.D., co-Founder, Institute for Transpersonal Psychology and author of The Other Side of Haight "Armstrong synthesizes an enormous amount of material from many fields and wisdom traditions to create a book that is fresh, provocative, and important. His holistic approach presents us with the largest possible map as we navigate across our own lives. Bravo, captain." — Mary Pipher, author of Writing to Change the World and Reviving Ophelia "Thomas Armstrong is an original thinker whose perceptions broaden our understanding of children, education and society. In The Human Odyssey, Armstrong provides a comprehensive framework for human development with characteristic depth and optimism." — Peggy O'Mara, Editor and Publisher of Mothering Magazine "This is truly a major contribution — brilliant, beguiling, and as broad in concept as it is deep." — Jean Houston, Ph.D. author of The Possible Human
Author: James Womack
Publisher: John Wiley & Sons
ISBN: 1118301706
Category : Science
Languages : en
Pages : 285
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Book Description
The genetic information being unlocked by advances in genomic and high throughput technologies is rapidly revolutionizing our understanding of developmental processes in bovine species. This information is allowing researchers unprecedented insight into the genetic basis of key traits. Bovine Genomics is the first book to bring together and synthesize the information learned through the bovine genome sequencing project and look at its practical application to cattle and dairy production. Bovine Genomics opens with foundational chapters on the domestication of cattle and traditional Mendelian genetics. Building on these chapters, coverage rapidly moves to quantitative genetics and the advances of whole genome technologies. Significant coverage is given to such topics as epigenetics, mapping quantitative trail loci, genome-wide association studies and genomic selection in cattle breeding. The book is a valuable synthesis of the field written by a global team of leading researchers. Providing wide-ranging coverage of the topic, Bovine Genomic, is an essential guide to the field. The basic and applied science will be of use to researchers, breeders, and advanced students.
Author: Dhavendra Kumar
Publisher: Academic Press
ISBN: 0127999221
Category : Science
Languages : en
Pages : 360
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Book Description
Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems
Author: Svante Pääbo
Publisher: Basic Books
ISBN: 0465080685
Category : Science
Languages : en
Pages : 290
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Book Description
A preeminent geneticist, winner of the 2022 Nobel Prize in medicine, hunts the Neanderthal and Denisovan genomes to answer the biggest question of them all: how did our ancestors become human? Neanderthal Man tells the riveting personal and scientific story of the quest to use ancient DNA to unlock the secrets of human evolution. Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA, Svante Pääbo. We learn that Neanderthal genes offer a unique window into the lives of our ancient relatives and may hold the key to unlocking the mysteries of where language came from as well as why humans survived while Neanderthals went extinct. Pääbo redrew our family tree and permanently changed the way we think about who we are and how we got here. For readers of Richard Dawkins, David Reich, and Hope Jahren, Neanderthal Man is the must-read account of how he did it.
Author: Timothy F. Murphy
Publisher: Univ of California Press
ISBN: 0520377931
Category : Medical
Languages : en
Pages : 195
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Book Description
The Human Genome Project is an expensive, ambitious, and controversial attempt to locate and map every one of the approximately 100,000 genes in the human body. If it works, and we are able, for instance, to identify markers for genetic diseases long before they develop, who will have the right to obtain such information? What will be the consequences for health care, health insurance, employability, and research priorities? And, more broadly, how will attitudes toward human differences be affected, morally and socially, by the setting of a genetic “standard”? The compatibility of individual rights and genetic fairness is challenged by the technological possibilities of the future, making it difficult to create an agenda for a “just genetics.” Beginning with an account of the utopian dreams and authoritarian tendencies of historical eugenics movements, this book’s nine essays probe the potential social uses and abuses of detailed genetic information. Lucid and wide-ranging, these contributions will interest bioethicists, legal scholars, and policy makers. Essays: “The Genome Project and the Meaning of Difference,” Timothy F. Murphy “Eugenics and the Human Genome Project: Is the Past Prologue?,” Daniel J. Kevles “Handle with Care: Race, Class, and Genetics,” Arthur L. Caplan “Public Choices and Private Choices: Legal Regulation of Genetic Testing,” Lori B. Andrews “Rules for Gene Banks: Protecting Privacy in the Genetics Age,” George J. Annas “Use of Genetic Information by Private Insurers,” Robert J. Pokorski “The Genome Project, Individual Differences, and Just Health Care,” Norman Daniels “Just Genetics: A Problem Agenda,” Leonard M. Fleck “Justice and the Limitations of Genetic Knowledge,” Marc A. Lappé This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1994.
Author: Gil Atzmon, PhD
Publisher: Springer
ISBN: 1493924044
Category : Medical
Languages : en
Pages : 199
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Book Description
The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.
