The CRF Signal

The CRF Signal PDF Author: Jay Schulkin
Publisher: Oxford University Press
ISBN: 0192512382
Category : Science
Languages : en
Pages : 352

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Book Description
Information molecules, such as Cortico-Releasing Factor (CRF), are ancient and widely distributed across diverse organs, playing various regulatory roles. CRF has been associated with a range of human conditions, including fear and anxiety, social contact, and most recently, addiction – in particular the euphoric feelings associated with alcohol consumption. Since its original discovery, research has unearthed that the role of this molecule is much broader than first thought. The scientific community now knows that CRF is a dynamic and diversely widespread peptide hormone that plays many roles and has many functions, in addition to its role as a releasing factor in the brain. This book explores the role of CRF, examining the relationship between location and function. It considers recurrent features that are linked to CRF - movement and change. CRF expression in regions of the brain is tied to paying attention to novel events and invoking movement in response to those events. Indeed, CRF provokes simple organized rhythmic behavior and can be mobilized under diverse conditions, including adversity. Examining the evolutionary origins of CRH, its neural functions, and its role in a variety of human characteristics and social behaviors, this book provides unique insights into CRF, and will be of interest to students and researchers in Neuroscience, Psychology, and Biology.

The CRF Signal

The CRF Signal PDF Author: Jay Schulkin
Publisher: Oxford University Press
ISBN: 0192512382
Category : Science
Languages : en
Pages : 352

Get Book

Book Description
Information molecules, such as Cortico-Releasing Factor (CRF), are ancient and widely distributed across diverse organs, playing various regulatory roles. CRF has been associated with a range of human conditions, including fear and anxiety, social contact, and most recently, addiction – in particular the euphoric feelings associated with alcohol consumption. Since its original discovery, research has unearthed that the role of this molecule is much broader than first thought. The scientific community now knows that CRF is a dynamic and diversely widespread peptide hormone that plays many roles and has many functions, in addition to its role as a releasing factor in the brain. This book explores the role of CRF, examining the relationship between location and function. It considers recurrent features that are linked to CRF - movement and change. CRF expression in regions of the brain is tied to paying attention to novel events and invoking movement in response to those events. Indeed, CRF provokes simple organized rhythmic behavior and can be mobilized under diverse conditions, including adversity. Examining the evolutionary origins of CRH, its neural functions, and its role in a variety of human characteristics and social behaviors, this book provides unique insights into CRF, and will be of interest to students and researchers in Neuroscience, Psychology, and Biology.

The CRF Signal

The CRF Signal PDF Author: Jay Schulkin
Publisher: Oxford University Press
ISBN: 0198793693
Category : Science
Languages : en
Pages : 353

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Book Description
"Information molecules such as corticotropin-releasing factor (CRF) are ancient and widely distributed across diverse organs. The scientific community is beginning to realize that CRF is a dynamic and diversely widespread peptide hormone (e.g. placenta) with many functions (parturtion, metamorphosis, circadian rhythmicity) beyond acting as a releasing factor in the brain. Indeed, CRF has been associated with a range of states of the brain, including fear and anxiety, social contact, and incentive salence and addiction. Examining the evolutionary origins of CRF, its diverse endocrine and neural functions, this book provides insights into CRF that will be of interest to students and researchers in the biological, medical and behavioral sciences."--Page 4 of cover.

Hormone Action and Signal Transduction in Endocrine Physiology and Disease

Hormone Action and Signal Transduction in Endocrine Physiology and Disease PDF Author: László Hunyady
Publisher: Frontiers Media SA
ISBN: 2889661008
Category : Medical
Languages : en
Pages : 134

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Modelling Biomedical Signals

Modelling Biomedical Signals PDF Author: Giuseppe Nardulli
Publisher: World Scientific
ISBN: 9814489441
Category : Technology & Engineering
Languages : en
Pages : 292

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Book Description
In the last few years, concepts and methodologies initially developed in physics have found high applicability in many different areas. This book, a result of cross-disciplinary interaction among physicists, biologists and physicians, covers several topics where methods and approaches rooted in physics are successfully applied to analyze and to model biomedical data. Included are papers on physiological rhythms and synchronization phenomena, gene expression patterns, the immune system, decision support systems in medical science, protein folding and protein crystallography. The volume can be used as a valuable reference for graduate students and researchers at the interface of physics, biology and medicine.The proceedings have been selected for coverage in:• Index to Scientific & Technical Proceedings (ISTP CDROM version / ISI Proceedings)

Amyloid and Related Disorders

Amyloid and Related Disorders PDF Author: Maria M. Picken
Publisher: Humana Press
ISBN: 3319192949
Category : Medical
Languages : en
Pages : 542

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Book Description
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.

The Brain as a Drug Target

The Brain as a Drug Target PDF Author: Shafiqur Rahman
Publisher: Academic Press
ISBN: 0123855071
Category : Medical
Languages : en
Pages : 468

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Book Description
The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Stress Science

Stress Science PDF Author: George Fink
Publisher: Academic Press
ISBN: 9780123785718
Category : Medical
Languages : en
Pages : 829

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Book Description
Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that explains the phenomenon of stress, the neural, endocrine and molecular mechanisms involved, the clinical effects, and the impact on individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing’s Syndrome: Addison’s Disease) and the adverse impact of stress on human physical and mental health . Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses and related disorders such as combat fatigue and burnout. The work covers interactions between stress and neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease, as well as stress-immune-inflammatory interactions in relation to cancer and autoimmune and viral diseases. Emphasis is also placed on the role of stress in obesity, hypertension, diabetes type II and other features of the metabolic syndrome which has now reached epidemic proportions in the USA and other countries. Chapters offer impressive scope with topics addressing animal studies, disaster, diurnal rhythms, drug effects and treatments, cognition and emotion, physical illness, psychopathology, immunology and inflammation, lab studies and tests, and psychological / biochemical / genetic aspects Richly illustrated with over 200 figures, 75 in color Priced affordably, this compendium of articles appeals to the end user interested in stress research who would not otherwise purchase the larger Encyclopedia of Stress Articles carefully selected by one of the world’s most preeminent stress researchers and contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Neural Information Processing

Neural Information Processing PDF Author: Minho Lee
Publisher: Springer
ISBN: 3642420516
Category : Computers
Languages : en
Pages : 655

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Book Description
The three volume set LNCS 8226, LNCS 8227, and LNCS 8228 constitutes the proceedings of the 20th International Conference on Neural Information Processing, ICONIP 2013, held in Daegu, Korea, in November 2013. The 180 full and 75 poster papers presented together with 4 extended abstracts were carefully reviewed and selected from numerous submissions. These papers cover all major topics of theoretical research, empirical study and applications of neural information processing research. The specific topics covered are as follows: cognitive science and artificial intelligence; learning theory, algorithms and architectures; computational neuroscience and brain imaging; vision, speech and signal processing; control, robotics and hardware technologies and novel approaches and applications.

Intercellular Communication in the Nervous System

Intercellular Communication in the Nervous System PDF Author: Robert Malenka
Publisher: Academic Press
ISBN: 0123785723
Category : Science
Languages : en
Pages : 776

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Book Description
Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signaling. * Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more * Richly illustrated in full color with over 200 figures * Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Exploiting genetics and genomics to improve the understanding of eye diseases

Exploiting genetics and genomics to improve the understanding of eye diseases PDF Author: Denis Plotnikov
Publisher: Frontiers Media SA
ISBN: 283253838X
Category : Science
Languages : en
Pages : 134

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Book Description