Tailor-Made Polysaccharides in Drug Delivery

Tailor-Made Polysaccharides in Drug Delivery PDF Author: Amit Kumar Nayak
Publisher: Academic Press
ISBN: 012821287X
Category : Medical
Languages : en
Pages : 416

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Book Description
Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery. - Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications - Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides - Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Tailor-Made Polysaccharides in Biomedical Applications

Tailor-Made Polysaccharides in Biomedical Applications PDF Author: Amit Kumar Nayak
Publisher: Academic Press
ISBN: 0128213566
Category : Medical
Languages : en
Pages : 360

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Book Description
Tailor-Made Polysaccharides in Biomedical Applications provides extensive details on all the vital precepts, basics, and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industries. This information provides readers with the foundation for understanding and developing high-quality products. The utilization of natural polymeric excipients in numerous healthcare applications demands the replacement of the synthetic polymers with natural polymers. Natural polymers are superior in terms of biocompatibility, biodegradability, economic extraction, and ready availability. Natural polymers are especially useful in that they are a renewable source of raw materials, as long as they are grown sustainably. Among these natural polymers, polysaccharides are considered as excellent excipients because they are nontoxic, stable, and biodegradable. Several research innovations have been carried out using polysaccharides in drug delivery applications. This book offers a comprehensive resource to understand the potential of these materials in forming new drug delivery methods. It will be useful to biomedical researchers, chemical engineers, regulatory scientists, and students who are actively involved in developing pharmaceutical products for biomedical applications by using tailor-made polysaccharides. - Provides methodology for the design, development, and selection of tailor-made polysaccharides in biomedical applications, including for particular therapeutic applications - Includes illustrations demonstrating the mechanism of biological interaction of tailor-made polysaccharides - Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

Natural Polysaccharides in Drug Delivery and Biomedical Applications

Natural Polysaccharides in Drug Delivery and Biomedical Applications PDF Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0128170565
Category : Medical
Languages : en
Pages : 656

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Book Description
Natural Polysaccharides in Drug Delivery and Biomedical Applications provides a fundamental overview of natural polysaccharides, their sources, extraction methodologies, and characterizations. It covers specific natural polysaccharides and their effective application in drug delivery and biomedical use. Additionally, chapters in the book discuss key topics including the sources and extraction methodologies of natural polysaccharides, their role in tissue engineering applications, polysaccharide-based nanoparticles in biomedical applications, and their role in the delivery of anticancer drugs. Written by industry leaders and edited by experts, this book emphasizes recent advances made in the field.Natural Polysaccharides in Drug Delivery and Biomedical Applications provides academics, researchers, and pharmaceutical health care professionals with a comprehensive book on polysaccharides in pharmaceutical delivery process. - Provides fundamental concepts of natural polysaccharides as it applies to the pharmaceutical, biomedical, and biotechnology industries - Includes contributions from global leaders and experts from academia, industry, and regulatory agencies in the application of natural polysaccharides in pharmaceutical products and biomedical utilization - Offers practical examples, illustrations, chemical structures, and research case studies to help explain natural polysaccharides concepts in drug delivery and biomedical applications

Alginates in Drug Delivery

Alginates in Drug Delivery PDF Author: Amit Kumar Nayak
Publisher: Academic Press
ISBN: 0128176415
Category : Medical
Languages : en
Pages : 436

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Book Description
Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers' biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. - Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields - Includes high quality illustrations, along with practical examples and research case studies - Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Plant Polysaccharides as Pharmaceutical Excipients

Plant Polysaccharides as Pharmaceutical Excipients PDF Author: Amit Kumar Nayak
Publisher: Elsevier
ISBN: 0323907814
Category : Technology & Engineering
Languages : en
Pages : 648

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Book Description
Plant Polysaccharides as Pharmaceutical Excipients explores innovative techniques and applications of plant-derived polysaccharides as pharmaceutical excipients. Plant polysaccharides are sustainable, renewable and abundantly available, offering attractive properties in terms of water solubility, swelling ability, non-toxicity and biodegradability. These qualities have resulted in extensive exploration into their applications as excipients in a variety of pharmaceutical dosage forms. This book takes a comprehensive, application-oriented approach, drawing on the very latest research that includes sources, classification and extraction methods of plant polysaccharides. Subsequent chapters focus on plant polysaccharides for individual pharmaceutical applications, enabling the reader to understand their preparation for specific targeted uses. Throughout the book, information is supported by illustrations, chemical structures, flow charts and data tables, providing a clear understanding. Finally, future perspectives and challenges are reviewed and discussed. - Explains sources, classifications, extraction methods and biocompatibility of plant polysaccharides - Guides the reader through properties and preparation methods of plant polysaccharides as pharmaceutical excipients - Covers a broad range of cutting-edge applications, with each chapter targeting a specific use

Chitosan in Drug Delivery

Chitosan in Drug Delivery PDF Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0128193379
Category : Medical
Languages : en
Pages : 557

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Book Description
Chitosan in Drug Delivery provides thorough insights into chitosan chemistry, collection, chemical modifications, characterization and applications in the pharmaceutical industry and healthcare fields. The book explores molecular weight, degree of deacetylation and molecular geometry, emphasizing recent advances in the field as written by academic, industry and regulatory scientists. It will be a useful resource for pharmaceutical scientists, including industrial pharmacists, analytical scientists, postgraduate students, health care professionals and regulatory scientists actively involved in pharmaceutical product and process development in natural polymers containing drug delivery. - Provides methodologies for the design, development and selection of chitosan in drug delivery for particular therapeutic applications - Includes illustrations demonstrating the mechanism of biological interaction of chitosan - Discusses the regulatory aspects and demonstrates the clinical efficacy of chitosan

Ionotropic Cross-Linking of Biopolymers

Ionotropic Cross-Linking of Biopolymers PDF Author: Amit Kumar Nayak
Publisher: Elsevier
ISBN: 0323996701
Category : Technology & Engineering
Languages : en
Pages : 742

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Book Description
Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications. Sections introduce the fundamentals of ionotropic cross-linking of biopolymers, including mechanisms, chemistry, cross-linking methods and gelation. Additional content delves into ionotropically cross-linked biopolymers based on a range of sources, including alginate, pectinate, carboxymethyl cellulose, gellan gum, chitosan, carboxymethylated gums, plant polysaccharide blends, and synthetic polymer blends. This is followed by a section focusing on ionotropically cross-linked biopolymeric systems, such as polymeric nanoparticles, microparticles, beads, and reinforced matrices.The last part of the book explores specific advanced drug delivery applications, before considering future opportunities and challenges in the field. This is a valuable resource for researchers and advanced students across polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry, as well as scientists and R&D personnel working in pharmacy, drug delivery, and materials for biomedicine. - Explains chemistry, mechanisms, preparation methods and applications of biopolymeric systems - Covers a range of biopolymer sources, including alginate, pectinate, gellan gum, chitosan, and others - Guides the reader to cutting-edge applications in drug delivery, drug release, cell delivery and tissue engineering

Handbook of Curatives and Crosslinkers

Handbook of Curatives and Crosslinkers PDF Author: George Wypych
Publisher: Elsevier
ISBN: 1774670399
Category : Science
Languages : en
Pages : 383

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Book Description
This 2nd edition of Handbook of Curatives and Crosslinkers presents the mechanisms of action of these additives, methods of their use, their effects on the properties of transformed products, as well as their applications. It outlines the most-recent information on additives that convert soluble monomers, prepolymers, or polymers to insoluble polymer networks commonly known as thermosetting polymers. Chapters cover the common use of curatives in many industrial products manufactured in large scale, such as adhesives, sealants, coatings, inks, explosives, propellants and foams, and in emerging products such as optoelectronics, light-emitting diodes, shape memory polymers, and more. In addition, crosslinkers used in typical industrial processing methods, such as solar cells, vulcanization, adhesives, foams, and roofing are covered. Each section presents the effect of the additive, including an evaluation of its chemical and physical properties. Also available is the complementary Databook of Curatives and Crosslinkers, Second Edition, which provides information on both the commercial and generic chemical products used as curatives and crosslinkers. - Covers the use of curatives in emerging products such as optoelectronics, light-emitting diodes, liquid crystal displays, self-healing materials, and in shape-memory materials - Presents emerging applications, such as drug release, artificial muscles in microdevices, autonomous shape-memory actuators, hygienic textiles, membranes, scaffolds, recycling, sensors, tissue adhesives, wound dressing, and more - Discusses the selection, chemical and physical properties, mechanics, and the effects of crosslinkers and curatives

Advanced Nanoformulations

Advanced Nanoformulations PDF Author: Md Saquib Hasnain
Publisher: Academic Press
ISBN: 0323885799
Category : Medical
Languages : en
Pages : 873

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Book Description
Advanced Nanoformulations: Theranostic Nanosystems, Volume Three examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the advanced formulations using nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on advanced formulations while also suggesting new avenues - Includes contributions in all areas of advanced formulations, providing a thorough and interdisciplinary work

Application of Gellan Gum as a Biomedical Polymer

Application of Gellan Gum as a Biomedical Polymer PDF Author: Amit Kumar Nayak
Publisher: Elsevier
ISBN: 0323972438
Category : Technology & Engineering
Languages : en
Pages : 586

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Book Description
Application of Gellan Gum as a Biomedical Polymer details key topics and fundamental aspects of gellan gum and its biomedical applications in drug delivery, proteins and peptides delivery, cell delivery, tissue engineering, wound dressings and enzyme immobilizations in developing high quality products. Sections introduce gellan gum, its source, production and gelation mechanism, discuss biomedical materials, and provides ways it can be used for biomedical applications. The book also examines the used of gellan gum as pharmaceutical excipients for drug delivery. Future developments and challenges round out the book's coverage.With contributions for an international group of experts, this book is a useful reference for scientists, researchers and those in industry engaged in biomedical product development using natural polysaccharides. - Discusses gellan gum-based materials such as hydrogels and nanosystems in biomedical applications - Describes gellan gum application in areas like tissue engineering, wound dressing, protein and peptide delivery, and as pharmaceutical excipients in drug delivery - Offers chapter contributions on gellan gum and its application from an international group of experts in research and industry