Suspended Silicon Nanowires for Highly Sensitive Biological and Chemical Sensing Applications PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Suspended Silicon Nanowires for Highly Sensitive Biological and Chemical Sensing Applications PDF full book. Access full book title Suspended Silicon Nanowires for Highly Sensitive Biological and Chemical Sensing Applications by Mohammad Adel Ghiass. Download full books in PDF and EPUB format.
Author: Mohammad Adel Ghiass
Publisher:
ISBN:
Category :
Languages : en
Pages : 159
Get Book Here
Book Description
Author: Mohammad Adel Ghiass
Publisher:
ISBN:
Category :
Languages : en
Pages : 159
Get Book Here
Book Description
Author: Jeffery L. Coffer
Publisher: Woodhead Publishing
ISBN: 0323851312
Category : Science
Languages : en
Pages : 442
Get Book Here
Book Description
In its second, extensively revised second edition, Semiconducting Silicon Nanowires for Biomedical Applications reviews the fabrication, properties, and biomedical applications of this key material. The book begins by reviewing the basics of growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires. Attention then turns to use of these structures for tissue engineering and delivery applications, followed by detection and sensing. Reflecting the evolution of this multidisciplinary subject, several new key topics are highlighted, including our understanding of the cell-nanowire interface, latest advances in associated morphologies (including silicon nanoneedles and nanotubes for therapeutic delivery), and significantly, the status of silicon nanowire commercialization in biotechnology. Semiconducting Silicon Nanowires for Biomedical Applications is a comprehensive resource for biomaterials scientists who are focused on biosensors, drug delivery, and the next generation of nano-biotech platforms that require a detailed understanding of the cell-nanowire interface, along with researchers and developers in industry and academia who are concerned with nanoscale biomaterials, in particular electronically-responsive structures. - Reviews the growth, characterization, biocompatibility, and surface modification of semiconducting silicon nanowires - Describes silicon nanowires for tissue engineering and delivery applications, including cellular binding & internalization, tissue engineering scaffolds, mediated differentiation of stem cells, and silicon nanoneedles & nanotubes for delivery of small molecule / biologic-based therapeutics - Highlights the use of silicon nanowires for detection and sensing - Presents a detailed description of our current understanding of the cell-nanowire interface - Covers the current status of commercial development of silicon nanowire-based platforms
Author: Maria E. Pace
Publisher:
ISBN:
Category :
Languages : en
Pages : 89
Get Book Here
Book Description
Abstract Silicon Nanowires for Chemical Sensing, pH Measurement and Ion Species Identification in Solution by Maria E. Pace Doctor of Philosophy in Applied Science and Technology University of California, Berkeley Professor Tarek I. Zohdi, Co-Chair Dean Albert P. Pisano, Co-Chair In situ measurement of true pH would be useful in many applications. True pH is the negative log of the Hydrogen ion concentration, however, measurement of this is elusive in many practical applications due to the presence of interfering ions, such as sodium and potassium. Monitoring true pH in surgical procedures, for instance, would be very useful, however, interfering ions necessitate preprocessing of the blood and laboratory analysis making it not in situ, and not in real time. This work presents a measurement system capable of measuring true pH in the presence of interfering ions using nanowire sensors and electrospectroscopy. This system is also able to operate as a chemical sensor by discriminating between different ionic species in solution and can separately measure concentrations of other ionic species for leak detection and chemical identification. Nanowire sensors offer many advantages such as small size, low power, and inexpensive fabrication. These advantages allow real time, in situ monitoring in many applications. In addition, silicon nanowires are integrated as a semiconductor pH sensor and species identification chip. Using electrospectroscopy, ions drift in the fluid at different times allowing the nanowire to make measurements of different species present in the fluid. To accomplish this, various modes of operation including “the time of flight” have been developed to maximize ion identification and species concentration measurement. The advantages of these sensors include high sensitivity at low concentrations, 80% sensitivity at 1e-6 M with ion species identification and measurement of true pH. Depending on the species of interest, a particular mode of operation can be employed to achieve desirable results. Advantages of these modes of operation are isolation of hydrogen ions from other species including sodium to measure true pH in real time and a method for deconvolving the species both in temporal and spatial maps. Additionally, a method for electrically cleaning the nanowires sensors and a method to re-zero the nanowires has been explored allowing more accurate measurement of the species and true pH. A novel top down fabrication process has been developed which reduces the line edge roughness of the nanowire for more reproducible sensors, reduces dielectric pin hole density for minimal sensor drift over time and reduces parasitic resistance for higher ion sensitivity. This novel fabrication process is truly CMOS compatible allowing more compatibility with other electronics. The SiNW is covered by thin film which protects SiNW from liquid penetration and can also work as ion sensitive film or functionalized surface. As a fabrication simplicity, the entire structure above can be built on a standard SOI (Silicon on Insulator) wafer. Experimental results have shown a linear relation between resistance change in the nanowire and pH in the fluid.
Author: Yuri Magarshak
Publisher: Springer Science & Business Media
ISBN: 9048125235
Category : Technology & Engineering
Languages : en
Pages : 427
Get Book Here
Book Description
Even though there is no generally accepted definition of nanotechnologies to be defined as distinct discipline there is an emerging consensus that their advent and development is a growing in importance factor of the contemporary and future technological civilization. One of these most fundamental issues we are confronted with is the compatibility with life itself. From single cell organisms to humans, carbon is a key building block of all molecular structures of life. In contrast the man created electronic industry to build on other elements, of which silicon is the most common. Both carbon and silicon create molecular chains, although different in their internal structure. All life is built from carbon-based chains. As long as the man built technological products do not directly interfere with the physiology of life the associated risks from them are relatively easy to identify. They are primarily in the environmental pollution and the possibility of upsetting the natural balance of biocoenosis, on a planetary scale. The basic life functions are still not directly subverted. We can use TV, computers, drive cars and use other technological utilities without fear of direct interference with our cellular functions. This is in particular because all these technological utilities are many orders of magnitude larger than typical scales of biological activity. Most of biological activity, from fermentative catalysis to DNA replication takes place on nanoscale. The situation is radically different when the technological goals are building nanoscale size products. All biological processes take place on nanoscale.
Author: Yu Chen
Publisher:
ISBN:
Category :
Languages : en
Pages : 208
Get Book Here
Book Description
Abstract: Detection and recognition of chemical ions and biological molecules are important in basic science as well as in pharmacology and medicine. Nanotechnology has made it possible to greatly enhance detection sensitivity through the use of nanowires, nanotubes, nanocrystals, nanocantilevers, and quantum dots as sensing platforms. In this work silicon nanowires are used as the conductance channel between the source and drain of a FET (field effect transistor) device and the biomolecular binding on the surface of nanowire modifies the conductance like a change in gate voltage. Due to the high surface-to-volume ratio and unique character of the silicon nanowires, this device has significant advantages in real-time, label-free and highly sensitive detection of a wide range of species, including proteins, nucleic acids and other small molecules. Here we present a biosensor fabricated from CMOS (complementary metal-oxide-semiconductor) compatible top-down methods including electron beam lithography. This method enables scalable manufacturing of multiple sensor arrays with high efficiency. In a systematic study of the device characteristics with different wire widths, we have found the sensitivity of the device increases when wire width decreases. By operating the device in appropriate bias region, the sensitivity of the device can be improved without doping or high temperature annealing. Not only can this device be used to detect the concentration of proteins and metabolites like urea or glucose, but also dynamic information like the dissociation constant can be extracted from the measurement. The device is also used to detect the clinically related cancer antigen CA 15.3 and shows potential application in cancer studies.
Author: Michael A. Carpenter
Publisher: Springer Science & Business Media
ISBN: 146145395X
Category : Science
Languages : en
Pages : 559
Get Book Here
Book Description
This book presents a state-of-the-art summary and critical analysis of work recently performed in leading research laboratories around the world on the implementation of metal oxide nanomaterial research methodologies for the discovery and optimization of new sensor materials and sensing systems. The book provides a detailed description and analysis of (i) metal oxide nanomaterial sensing principles, (ii) advances in metal oxide nanomaterial synthesis/deposition methods, including colloidal, emulsification, and vapor processing techniques, (iii) analysis of techniques utilized for the development of low temperature metal oxide nanomaterial sensors, thus enabling a broader impact into sensor applications, (iv) advances, challenges and insights gained from the in situ/ex situ analysis of reaction mechanisms, and (v) technical development and integration challenges in the fabrication of sensing arrays and devices.
Author: Mun'delanji C. Vestergaard
Publisher: Springer
ISBN: 4431551905
Category : Science
Languages : en
Pages : 380
Get Book Here
Book Description
This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and development of nanobioelectronics are discussed in detail in Part III with examples from screen-printed electrodes, nanocarbon films, and semiconductor quantum dots. Part IV reviews the current applications of carbon nanotubes, nanoneedles, plasmonic sensors, electrochemical scanning microscopes, and field-effect transistors with the future outlook for emerging technologies. Attention is also given to potential challenges, in particular, of taking these technologies at the point-of-need. The book concludes by providing a condensed summary of the contents, with emphasis on future directions. Nanomaterials have become an essential part of biosensors and bioanalyses in the detection and monitoring of medical, pharmaceutical, and environmental conditions, from cancer to chemical warfare agents. This book, with its distinguished editors and international team of expert contributors, will be an essential guide for all those involved in the research, design, development, and application of nanomaterials in biosensors and bioanalyses.
Author: Shunri Oda
Publisher: CRC Press
ISBN: 1482228688
Category : Technology & Engineering
Languages : en
Pages : 288
Get Book Here
Book Description
Is Bigger Always Better? Explore the Behavior of Very Small Devices as Described by Quantum Mechanics Smaller is better when it comes to the semiconductor transistor. Nanoscale Silicon Devices examines the growth of semiconductor device miniaturization and related advances in material, device, circuit, and system design, and highlights the use of device scaling within the semiconductor industry. Device scaling, the practice of continuously scaling down the size of metal-oxide-semiconductor field-effect transistors (MOSFETs), has significantly improved the performance of small computers, mobile phones, and similar devices. The practice has resulted in smaller delay time and higher device density in a chip without an increase in power consumption. This book covers recent advancements and considers the future prospects of nanoscale silicon (Si) devices. It provides an introduction to new concepts (including variability in scaled MOSFETs, thermal effects, spintronics-based nonvolatile computing systems, spin-based qubits, magnetoelectric devices, NEMS devices, tunnel FETs, dopant engineering, and single-electron transfer), new materials (such as high-k dielectrics and germanium), and new device structures in three dimensions. It covers the fundamentals of such devices, describes the physics and modeling of these devices, and advocates further device scaling and minimization of energy consumption in future large-scale integrated circuits (VLSI). Additional coverage includes: Physics of nm scaled devices in terms of quantum mechanics Advanced 3D transistors: tri-gate structure and thermal effects Variability in scaled MOSFET Spintronics on Si platform NEMS devices for switching, memory, and sensor applications The concept of ballistic transport The present status of the transistor variability and more An indispensable resource, Nanoscale Silicon Devices serves device engineers and academic researchers (including graduate students) in the fields of electron devices, solid-state physics, and nanotechnology.
Author: Cindy Schmädicke
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Rakesh K. Sindhu
Publisher: CRC Press
ISBN: 1000258351
Category : Science
Languages : en
Pages : 496
Get Book Here
Book Description
This book gives a summary of the rapidly growing field of nanotechnology and includes materials and technologies that help in developing particles of various sizes, which can be utilized in different areas of research. It discusses the role of nanotechnology in different aspects, such as healthcare, especially in target-specific drug therapy for managing a number of medical disorders; agriculture, for developing smart field systems; and food industry, for improving and stabilizing the quality, healthiness, and shelf life of food. Being multidisciplinary, this book brings together the principles, theory, practices, and applications of not only nanotechnology but also those of nanobiotechnology, pharmaceuticals, food packaging, biosensors, and electronic devices. The book will be an exhilarating read for advanced undergraduate- and graduate-level students, general readers interested in nanotechnology, and researchers in chemistry, biology, and engineering. The scope of the book extends from basic research in physics, chemistry, and biology, including computational work and simulations, through to the development of new devices and technologies for applications in a wide range of industrial sectors (including information technology, medicine, manufacturing, high-performance materials, and energy and environmental technologies). It covers organic, inorganic, and hybrid materials and is an interdisciplinary book.
