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Author: A.John Bailer
Publisher: Routledge
ISBN: 1351414135
Category : Mathematics
Languages : en
Pages : 600
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Book Description
Statistics for Environmental Biology and Toxicology presents and illustrates statistical methods appropriate for the analysis of environmental data obtained in biological or toxicological experiments. Beginning with basic probability and statistical inferences, this text progresses through non-linear and generalized linear models, trend testing, time-to-event data and analysis of cross-classified tabular and categorical data. For the more complex analyses, extensive examples including SAS and S-PLUS programming code are provided to assist the reader when implementing the methods in practice.
Author: A.John Bailer
Publisher: Routledge
ISBN: 1351414135
Category : Mathematics
Languages : en
Pages : 600
Get Book Here
Book Description
Statistics for Environmental Biology and Toxicology presents and illustrates statistical methods appropriate for the analysis of environmental data obtained in biological or toxicological experiments. Beginning with basic probability and statistical inferences, this text progresses through non-linear and generalized linear models, trend testing, time-to-event data and analysis of cross-classified tabular and categorical data. For the more complex analyses, extensive examples including SAS and S-PLUS programming code are provided to assist the reader when implementing the methods in practice.
Author: A. John Bailer
Publisher: Routledge
ISBN: 1351414143
Category : Mathematics
Languages : en
Pages : 596
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Book Description
Statistics for Environmental Biology and Toxicology presents and illustrates statistical methods appropriate for the analysis of environmental data obtained in biological or toxicological experiments. Beginning with basic probability and statistical inferences, this text progresses through non-linear and generalized linear models, trend testing, time-to-event data and analysis of cross-classified tabular and categorical data. For the more complex analyses, extensive examples including SAS and S-PLUS programming code are provided to assist the reader when implementing the methods in practice.
Author: Lech Chyczewski
Publisher: IOS Press
ISBN: 9781586032180
Category : Medical
Languages : en
Pages : 380
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Book Description
This work is devoted to the study of the endocrine-related effects on human health with special reference to carcinogenesis, and to the assessment of carcinogenic risk. After providing basic information at the general, cellular and molecular levels, the contents focus on the paradigm of biologically-based risk assessment, as developed form physiologically-based toxicokinetic models. The analysis of this material is proposed as the novel parameters for developing biologically-based models of carcinogenesis, considered to be more relevant to risk assessment than traditional approaches.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264090894
Category :
Languages : en
Pages : 25
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Book Description
This Test Guideline describes procedures designed to estimate the acute oral toxicity of substances to birds, and it provides three testing options: (1) limit dose test, (2) LD50-slope test, and (3) LD50-only test. The LD50-slope and LD50-only ...
Author: Walter W. Piegorsch
Publisher: John Wiley & Sons
ISBN: 0470012226
Category : Mathematics
Languages : en
Pages : 512
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Book Description
Environmental statistics is a rapidly growing field, supported by advances in digital computing power, automated data collection systems, and interactive, linkable Internet software. Concerns over public and ecological health and the continuing need to support environmental policy-making and regulation have driven a concurrent explosion in environmental data analysis. This textbook is designed to address the need for trained professionals in this area. The book is based on a course which the authors have taught for many years, and prepares students for careers in environmental analysis centered on statistics and allied quantitative methods of data evaluation. The text extends beyond the introductory level, allowing students and environmental science practitioners to develop the expertise to design and perform sophisticated environmental data analyses. In particular, it: Provides a coherent introduction to intermediate and advanced methods for modeling and analyzing environmental data. Takes a data-oriented approach to describing the various methods. Illustrates the methods with real-world examples Features extensive exercises, enabling use as a course text. Includes examples of SAS computer code for implementation of the statistical methods. Connects to a Web site featuring solutions to exercises, extra computer code, and additional material. Serves as an overview of methods for analyzing environmental data, enabling use as a reference text for environmental science professionals. Graduate students of statistics studying environmental data analysis will find this invaluable as will practicing data analysts and environmental scientists including specialists in atmospheric science, biology and biomedicine, chemistry, ecology, environmental health, geography, and geology.
Author: William J. Brock
Publisher: John Wiley & Sons
ISBN: 1118874080
Category : Science
Languages : en
Pages : 568
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Book Description
A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book: Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP), compliance with guidelines, and animal models Features a concluding chapter that compiles case studies / lessons learned from those that have served as a Study Director for many years Addresses the entire spectrum of nonclinical testing, making it applicable to those in the government, laboratories and those actively involved in in all sectors of industry
Author: Michael C. Newman
Publisher: CRC Press
ISBN: 1439835640
Category : Science
Languages : en
Pages : 595
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Book Description
Quantitative Ecotoxicology, Second Edition explores models and methods of quantitative ecotoxicology at progressively higher biological scales using worked examples and common software packages. It complements the author’s previous books, Fundamentals of Ecotoxicology, Third Edition and Ecotoxicology: A Comprehensive Treatment. Encouraging a more rigorous inferential approach to research, the book examines the quantitative features of the science of ecotoxicology. The first chapters lay the foundation by introducing fundamental concepts and definitions. The author traces the historical perspective, rationale, and characteristics of scientific ecotoxicology as well as the general measurement process. He also considers methodologies for defining and controlling variance, which could otherwise exclude valid conclusions from ecotoxicological endeavors. The book then discusses ecotoxicological concepts at increasing levels of ecological organization and outlines quantitative methods used to measure toxicant accumulation and effects. Reflecting the importance of establishing type I and type II error rates, it highlights design issues, particularly sample size and power estimation. The final chapter summarizes the book with a brief discussion of ecotoxicology from a nonregulatory perspective. Extensively updated, this second edition has been expanded to include terrestrial as well as aquatic ecotoxicology. Requiring only a basic knowledge of statistics, this highly readable book is suitable for graduate students and researchers as well as practicing environmental scientists and engineers. It guides readers to better understand the fate and effects of toxicants in the biosphere—and helps them frame this understanding in quantitative terms. What’s New in This Edition More than 40 new figures and 20 new worked examples Updated measurement quality methods and software Expanded coverage of synecological models and methods More integration of Bayesian concepts Appendices for power analysis and basic matrix methods Additional mixture toxicity and up-and-down methods Greatly expanded discussion of significance testing Expanded discussion of metapopulations Matrix tools for population demography Light isotope-based models for trophic transfer of toxicants Inclusion of metacommunity and SHE analysis techniques R script examples by Eduard Szöcs (University Koblenz-Landau) available at http://edild.github.io/blog/categories/quantitative-ecotoxicology-with-r/
Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
ISBN: 111974296X
Category : Technology & Engineering
Languages : en
Pages : 1319
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Book Description
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
Author: Wayne Landis
Publisher: CRC Press
ISBN: 1498750443
Category : Science
Languages : en
Pages : 470
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Book Description
The fifth edition includes new sections on the use of adverse outcome pathways, how climate change changes how we think about toxicology, and a new chapter on contaminants of emerging concern. Additional information is provided on the derivation of exposure-response curves to describe toxicity and they are compared to the use of hypothesis testing. The text is unified around the theme of describing the entire cause-effect pathway from the importance of chemical structure in determining exposure and interaction with receptors to the use of complex systems and hierarchical patch dynamic theory to describe effects to landscapes.
Author: Walter W. Piegorsch
Publisher: John Wiley & Sons
ISBN: 9780470848364
Category : Mathematics
Languages : en
Pages : 520
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Book Description
Environmental statistics is a rapidly growing field, supported by advances in digital computing power, automated data collection systems, and interactive, linkable Internet software. Concerns over public and ecological health and the continuing need to support environmental policy-making and regulation have driven a concurrent explosion in environmental data analysis. This textbook is designed to address the need for trained professionals in this area. The book is based on a course which the authors have taught for many years, and prepares students for careers in environmental analysis centered on statistics and allied quantitative methods of data evaluation. The text extends beyond the introductory level, allowing students and environmental science practitioners to develop the expertise to design and perform sophisticated environmental data analyses. In particular, it: Provides a coherent introduction to intermediate and advanced methods for modeling and analyzing environmental data. Takes a data-oriented approach to describing the various methods. Illustrates the methods with real-world examples Features extensive exercises, enabling use as a course text. Includes examples of SAS computer code for implementation of the statistical methods. Connects to a Web site featuring solutions to exercises, extra computer code, and additional material. Serves as an overview of methods for analyzing environmental data, enabling use as a reference text for environmental science professionals. Graduate students of statistics studying environmental data analysis will find this invaluable as will practicing data analysts and environmental scientists including specialists in atmospheric science, biology and biomedicine, chemistry, ecology, environmental health, geography, and geology.
